Daratumumab, lenalidomide, bortezomib, and dexamethasone for transplant-eligible newly diagnosed multiple myeloma: the GRIFFIN trial von Voorhees, Peter M., Kaufman, Jonathan L., Laubach, Jacob, Sborov, Douglas W., Reeves, Brandi, Rodriguez, Cesar, Chari, Ajai, Silbermann, Rebecca, Costa, Luciano J., Anderson, Larry D., Nathwani, Nitya, Shah, Nina, Efebera, Yvonne A., Holstein, Sarah A., Costello, Caitlin, Jakubowiak, Andrzej, Wildes, Tanya M., Orlowski, Robert Z., Shain, Kenneth H., Cowan, Andrew J., Murphy, Sean, Lutska, Yana, Pei, Huiling, Ukropec, Jon, Vermeulen, Jessica, de Boer, Carla, Hoehn, Daniela, Lin, Thomas S., Richardson, Paul G.

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Downregulation of Death-Associated Protein Kinase 1 (DAPK1) in Chronic Lymphocytic Leukemia von Raval, Aparna, Tanner, Stephan M., Byrd, John C., Angerman, Elizabeth B., Perko, James D., Chen, Shih-Shih, Hackanson, Björn, Grever, Michael R., Lucas, David M., Matkovic, Jennifer J., Lin, Thomas S., Kipps, Thomas J., Murray, Fiona, Weisenburger, Dennis, Sanger, Warren, Lynch, Jane, Watson, Patrice, Jansen, Mary, Yoshinaga, Yuko, Rosenquist, Richard, de Jong, Pieter J., Coggill, Penny, Beck, Stephan, Lynch, Henry, de la Chapelle, Albert, Plass, Christoph

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Phase II Study of Flavopiridol in Relapsed Chronic Lymphocytic Leukemia Demonstrating High Response Rates in Genetically High-Risk Disease von Lin, Thomas S., Ruppert, Amy S., Johnson, Amy J., Fischer, Beth, Heerema, Nyla A., Andritsos, Leslie A., Blum, Kristie A., Flynn, Joseph M., Jones, Jeffrey A., Hu, Weihong, Moran, Mollie E., Mitchell, Sarah M., Smith, Lisa L., Wagner, Amy J., Raymond, Chelsey A., Schaaf, Larry J., Phelps, Mitch A., Villalona-Calero, Miguel A., Grever, Michael R., Byrd, John C.

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The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo von Lucas, David M., Edwards, Ryan B., Lozanski, Gerard, West, Derek A., Shin, Jungook D., Vargo, Melissa A., Davis, Melanie E., Rozewski, Darlene M., Johnson, Amy J., Su, Bao-Ning, Goettl, Virginia M., Heerema, Nyla A., Lin, Thomas S., Lehman, Amy, Zhang, Xiaoli, Jarjoura, David, Newman, David J., Byrd, John C., Kinghorn, A. Douglas, Grever, Michael R.

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Clinical response and pharmacokinetics from a phase 1 study of an active dosing schedule of flavopiridol in relapsed chronic lymphocytic leukemia von Phelps, Mitch A., Lin, Thomas S., Johnson, Amy J., Hurh, Eunju, Rozewski, Darlene M., Farley, Katherine L., Wu, Di, Blum, Kristie A., Fischer, Beth, Mitchell, Sarah M., Moran, Mollie E., Brooker-McEldowney, Michelle, Heerema, Nyla A., Jarjoura, David, Schaaf, Larry J., Byrd, John C., Grever, Michael R., Dalton, James T.

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Impact of Age on Outcomes After Initial Therapy With Chemotherapy and Different Chemoimmunotherapy Regimens in Patients With Chronic Lymphocytic Leukemia: Results of Sequential Can... von WOYACH, Jennifer A, RUPPERT, Amy S, LARSON, Richard A, BYRD, John C, RAI, Kanti, LIN, Thomas S, GEYER, Susan, KOLITZ, Jonathan, APPELBAUM, Frederick R, TALLMAN, Martin S, BELCH, Andrew R, MORRISON, Vicki A

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Daratumumab-based quadruplet therapy for transplant-eligible newly diagnosed multiple myeloma with high cytogenetic risk von Callander, Natalie S., Silbermann, Rebecca, Kaufman, Jonathan L., Godby, Kelly N., Laubach, Jacob, Schmidt, Timothy M., Sborov, Douglas W., Medvedova, Eva, Reeves, Brandi, Dhakal, Binod, Rodriguez, Cesar, Chhabra, Saurabh, Chari, Ajai, Bal, Susan, Anderson, Larry D., Dholaria, Bhagirathbhai R., Nathwani, Nitya, Hari, Parameswaran, Shah, Nina, Bumma, Naresh, Holstein, Sarah A., Costello, Caitlin, Jakubowiak, Andrzej, Wildes, Tanya M., Orlowski, Robert Z., Shain, Kenneth H., Cowan, Andrew J., Pei, Huiling, Cortoos, Annelore, Patel, Sharmila, Lin, Thomas S., Giri, Smith, Costa, Luciano J., Usmani, Saad Z., Richardson, Paul G., Voorhees, Peter M.

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Daratumumab plus RVd for newly diagnosed multiple myeloma: final analysis of the safety run-in cohort of GRIFFIN von Voorhees, Peter M., Rodriguez, Cesar, Reeves, Brandi, Nathwani, Nitya, Costa, Luciano J., Lutska, Yana, Bobba, Padma, Hoehn, Daniela, Pei, Huiling, Ukropec, Jon, Qi, Ming, Lin, Thomas S., Richardson, Paul G.

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Daratumumab in transplant-eligible patients with newly diagnosed multiple myeloma: final analysis of clinically relevant subgroups in GRIFFIN von Chari, Ajai, Kaufman, Jonathan L., Laubach, Jacob, Sborov, Douglas W., Reeves, Brandi, Rodriguez, Cesar, Silbermann, Rebecca, Costa, Luciano J., Anderson, Larry D., Nathwani, Nitya, Shah, Nina, Bumma, Naresh, Holstein, Sarah A., Costello, Caitlin, Jakubowiak, Andrzej, Wildes, Tanya M., Orlowski, Robert Z., Shain, Kenneth H., Cowan, Andrew J., Pei, Huiling, Cortoos, Annelore, Patel, Sharmila, Lin, Thomas S., Voorhees, Peter M., Usmani, Saad Z., Richardson, Paul G.

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Phase 1 Study of Lumiliximab with Detailed Pharmacokinetic and Pharmacodynamic Measurements in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia von BYRD, John C, O'BRIEN, Susan, MOLINA, Arturo, LEIGH, Bryan, HARRIS, Sarah, FLINN, Lan W, KIPPS, Thomas J, WEISS, Mark, KANTI RAI, LIN, Thomas S, WOODWORTH, James, WYNNE, Dee, REID, Jennifer

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Flavopiridol, Fludarabine, and Rituximab in Mantle Cell Lymphoma and Indolent B-Cell Lymphoproliferative Disorders von LIN, Thomas S, BLUM, Kristie A, SCHAAF, Larry J, GREVER, Michael R, BYRD, John C, BETH FISCHER, Diane, MITCHELL, Sarah M, RUPPERT, Amy S, PORCU, Pierluigi, KRAUT, Eric H, BAIOCCHI, Robert A, MORAN, Mollie E, JOHNSON, Amy J

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Consolidation Therapy With Subcutaneous Alemtuzumab After Fludarabine and Rituximab Induction Therapy for Previously Untreated Chronic Lymphocytic Leukemia: Final Analysis of CALGB... von LIN, Thomas S, DONOHUE, Kathleen A, BYRD, John C, LUCAS, Margaret S, HOKE, Eva E, BENGTSON, Elizabeth M, RAI, Kanti R, ATKINS, James N, LINK, Brian K, LARSON, Richard A

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Flavopiridol pharmacogenetics: clinical and functional evidence for the role of SLCO1B1/OATP1B1 in flavopiridol disposition von Ni, Wenjun, Ji, Jia, Dai, Zunyan, Papp, Audrey, Johnson, Amy J, Ahn, Sunjoo, Farley, Katherine L, Lin, Thomas S, Dalton, James T, Li, Xiaobai, Jarjoura, David, Byrd, John C, Sadee, Wolfgang, Grever, Michael R, Phelps, Mitch A

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Mcl-1 Is a Relevant Therapeutic Target in Acute and Chronic Lymphoid Malignancies: Down-Regulation Enhances Rituximab-Mediated Apoptosis and Complement-Dependent Cytotoxicity von HUSSAIN, Syed-Rehan A, CHENEY, Carolyn M, JOHNSON, Amy J, LIN, Thomas S, GREVER, Michael R, CALIGIURI, Michael A, LUCAS, David M, BYRD, John C

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Daratumumab plus lenalidomide/bortezomib/dexamethasone in Black patients with transplant-eligible newly diagnosed multiple myeloma in GRIFFIN von Nooka, Ajay K., Kaufman, Jonathan L., Rodriguez, Cesar, Jakubowiak, Andrzej, Efebera, Yvonne, Reeves, Brandi, Wildes, Tanya, Holstein, Sarah A., Anderson, Larry D., Badros, Ashraf, Shune, Leyla, Chari, Ajai, Pei, Huiling, Cortoos, Annelore, Patel, Sharmila, Bartlett, J. Blake, Vermeulen, Jessica, Lin, Thomas S., Richardson, Paul G., Voorhees, Peter

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Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia von Chen, Shih-Shih, Raval, Aparna, Johnson, Amy J, Hertlein, Erin, Liu, Te-Hui, Jin, Victor X, Sherman, Mara H, Liu, Shu-Jun, Dawson, David W, Williams, Katie E, Lanasa, Mark, Liyanarachchi, Sandya, Lin, Thomas S, Marcucci, Guido, Pekarsky, Yuri, Davuluri, Ramana, Croce, Carlo M, Guttridge, Denis C, Teitell, Michael A, Byrd, John C, Plass, Christoph

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STAT signaling in the pathogenesis and treatment of leukemias von Lin, T S, Mahajan, S, Frank, D A

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Ofatumumab: a novel monoclonal anti-CD20 antibody von Lin, Thomas S

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Once-weekly ofatumumab in untreated or relapsed Waldenström's macroglobulinaemia: an open-label, single-arm, phase 2 study von Furman, Richard R, Dr, Eradat, Herbert A, MD, DiRienzo, Christine G, PhD, Hofmeister, Craig C, MD, Hayman, Suzanne R, MD, Leonard, John P, Prof, Coleman, Morton, Prof, Advani, Ranjana, Prof, Chanan-Khan, Asher, MD, Switzky, Julie, MSN, Liao, Qiming M, PhD, Shah, Damini, BSc, Jewell, Roxanne C, PhD, Lisby, Steen, MD, Lin, Thomas S, MD

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Daratumumab, bortezomib, cyclophosphamide and dexamethasone in newly diagnosed and relapsed multiple myeloma: LYRA study von Yimer, Habte, Melear, Jason, Faber, Edward, Bensinger, William I., Burke, John M., Narang, Mohit, Stevens, Don, Gunawardena, Sriya, Lutska, Yana, Qi, Keqin, Ukropec, Jon, Qi, Ming, Lin, Thomas S., Rifkin, Robert M.

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