NUP98 and KMT2A : usually the bride rather than the bridesmaid von Fagnan, Alexandre, Mercher, Thomas

Volltext

SPEN integrates transcriptional and epigenetic control of X-inactivation von Dossin, François, Pinheiro, Inês, Żylicz, Jan J., Roensch, Julia, Collombet, Samuel, Le Saux, Agnès, Chelmicki, Tomasz, Attia, Mikaël, Kapoor, Varun, Zhan, Ye, Dingli, Florent, Loew, Damarys, Mercher, Thomas, Dekker, Job, Heard, Edith

Volltext

From hypoxia single‐cell gene signatures to HIF targeting of AML leukemic stem cells von Mercher, Thomas, Schwaller, Juerg

Volltext

TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS von Deplus, Rachel, Delatte, Benjamin, Schwinn, Marie K, Defrance, Matthieu, Méndez, Jacqui, Murphy, Nancy, Dawson, Mark A, Volkmar, Michael, Putmans, Pascale, Calonne, Emilie, Shih, Alan H, Levine, Ross L, Bernard, Olivier, Mercher, Thomas, Solary, Eric, Urh, Marjeta, Daniels, Danette L, Fuks, François

Volltext

Pediatric Acute Myeloid Leukemia (AML): From Genes to Models Toward Targeted Therapeutic Intervention von Mercher, Thomas, Schwaller, Juerg

Volltext

TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis von Quivoron, Cyril, Couronné, Lucile, Della Valle, Véronique, Lopez, Cécile K., Plo, Isabelle, Wagner-Ballon, Orianne, Do Cruzeiro, Marcio, Delhommeau, Francois, Arnulf, Bertrand, Stern, Marc-Henri, Godley, Lucy, Opolon, Paule, Tilly, Hervé, Solary, Eric, Duffourd, Yannis, Dessen, Philippe, Merle-Beral, Hélène, Nguyen-Khac, Florence, Fontenay, Michaëla, Vainchenker, William, Bastard, Christian, Mercher, Thomas, Bernard, Olivier A.

Volltext

Acquired initiating mutations in early hematopoietic cells of CLL patients von Damm, Frederik, Mylonas, Elena, Cosson, Adrien, Yoshida, Kenichi, Della Valle, Véronique, Mouly, Enguerran, Diop, M'boyba, Scourzic, Laurianne, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Miyano, Satoru, Kikushige, Yoshikane, Davi, Frederick, Lambert, Jérôme, Gautheret, Daniel, Merle-Béral, Hélène, Sutton, Laurent, Dessen, Philippe, Solary, Eric, Akashi, Koichi, Vainchenker, William, Mercher, Thomas, Droin, Nathalie, Ogawa, Seishi, Nguyen-Khac, Florence, Bernard, Olivier A

Volltext

Nuclear interacting SET domain protein 1 inactivation impairs GATA1-regulated erythroid differentiation and causes erythroleukemia von Leonards, Katharina, Almosailleakh, Marwa, Tauchmann, Samantha, Bagger, Frederik Otzen, Thirant, Cécile, Juge, Sabine, Bock, Thomas, Méreau, Hélène, Bezerra, Matheus F., Tzankov, Alexandar, Ivanek, Robert, Losson, Régine, Peters, Antoine H. F. M., Mercher, Thomas, Schwaller, Juerg

Volltext

1006 – TRANSCRIPTIONAL ALTERATIONS AND ONTOGENY IN PEDIATRIC ACUTE MYELOID LEUKEMIA von Mercher, Thomas

Volltext

ETO2-GLIS2 Hijacks Transcriptional Complexes to Drive Cellular Identity and Self-Renewal in Pediatric Acute Megakaryoblastic Leukemia von Thirant, Cécile, Ignacimouttou, Cathy, Lopez, Cécile K., Diop, M’Boyba, Le Mouël, Lou, Thiollier, Clarisse, Siret, Aurélie, Dessen, Phillipe, Aid, Zakia, Rivière, Julie, Rameau, Philippe, Lefebvre, Céline, Khaled, Mehdi, Leverger, Guy, Ballerini, Paola, Petit, Arnaud, Raslova, Hana, Carmichael, Catherine L., Kile, Benjamin T., Soler, Eric, Crispino, John D., Wichmann, Christian, Pflumio, Françoise, Schwaller, Jürg, Vainchenker, William, Lobry, Camille, Droin, Nathalie, Bernard, Olivier A., Malinge, Sébastien, Mercher, Thomas

Volltext

MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia von Pikman, Yana, Lee, Benjamin H, Mercher, Thomas, McDowell, Elizabeth, Ebert, Benjamin L, Gozo, Maricel, Cuker, Adam, Wernig, Gerlinde, Moore, Sandra, Galinsky, Ilene, DeAngelo, Daniel J, Clark, Jennifer J, Lee, Stephanie J, Golub, Todd R, Wadleigh, Martha, Gilliland, D Gary, Levine, Ross L

Volltext

RUNX1-induced silencing of non-muscle myosin heavy chain IIB contributes to megakaryocyte polyploidization von Lordier, Larissa, Bluteau, Dominique, Jalil, Abdelali, Legrand, Céline, Pan, Jiajia, Rameau, Philippe, Jouni, Dima, Bluteau, Olivier, Mercher, Thomas, Leon, Catherine, Gachet, Christian, Debili, Najet, Vainchenker, William, Raslova, Hana, Chang, Yunhua

Volltext

Efficacy of DYRK1A inhibitors in novel models of Down syndrome acute lymphoblastic leukemia von Carey-Smith, Shannon L, Simad, Maryam H, Panchal, Kunjal, Aya-Bonilla, Carlos, Smolders, Hannah, Lin, Sang, Armitage, Jesse D, Nguyen, Vivien T, Bentley, Kathryn, Ford, Jette, Singh, Sajla, Oommen, Joyce, Laurent, Anouchka P, Mercher, Thomas, Crispino, John D, Montgomery, Andrew P, Kassiou, Michael, Besson, Thierry, Deau, Emmanuel, Meijer, Laurent, Cheung, Laurence C, Kotecha, Rishi S, Malinge, Sébastien

Volltext

Developmental interplay between transcriptional alterations and a targetable cytokine signaling dependency in pediatric ETO2::GLIS2 leukemia von Alonso-Pérez, Verónica, Galant, Klaudia, Boudia, Fabien, Robert, Elie, Aid, Zakia, Renou, Laurent, Barroca, Vilma, Devanand, Saryiami, Babin, Loélia, Rouiller-Fabre, Virginie, Moison, Delphine, Busso, Didier, Piton, Guillaume, Metereau, Christophe, Abermil, Nassera, Ballerini, Paola, Hirsch, Pierre, Haddad, Rima, Martinovic, Jelena, Petit, Arnaud, Lapillonne, Hélène, Brunet, Erika, Mercher, Thomas, Pflumio, Françoise

Volltext

Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene-Driven Myeloid Leukemia von Lopez, Cécile K, Noguera, Esteve, Stavropoulou, Vaia, Robert, Elie, Aid, Zakia, Ballerini, Paola, Bilhou-Nabera, Chrystèle, Lapillonne, Hélène, Boudia, Fabien, Thirant, Cécile, Fagnan, Alexandre, Arcangeli, Marie-Laure, Kinston, Sarah J, Diop, M'Boyba, Job, Bastien, Lecluse, Yann, Brunet, Erika, Babin, Loélia, Villeval, Jean Luc, Delabesse, Eric, Peters, Antoine H F M, Vainchenker, William, Gaudry, Muriel, Masetti, Riccardo, Locatelli, Franco, Malinge, Sébastien, Nerlov, Claus, Droin, Nathalie, Lobry, Camille, Godin, Isabelle, Bernard, Olivier A, Göttgens, Berthold, Petit, Arnaud, Pflumio, Françoise, Schwaller, Juerg, Mercher, Thomas

Volltext

Corrigendum: Pediatric Acute Myeloid Leukemia (AML): From Genes to Models Toward Targeted Therapeutic Intervention von Mercher, Thomas, Schwaller, Juerg

Volltext

JAK3: A two-faced player in hematological disorders von Cornejo, Melanie G., Boggon, Titus J., Mercher, Thomas

Volltext

Notch signaling specifies megakaryocyte development from hematopoietic stem cells von Mercher, Thomas, Cornejo, Melanie G, Sears, Christopher, Kindler, Thomas, Moore, Sandra A, Maillard, Ivan, Pear, Warren S, Aster, Jon C, Gilliland, D Gary

Volltext

Activating alleles of JAK3 in acute megakaryoblastic leukemia von Walters, Denise K., Mercher, Thomas, Gu, Ting-Lei, O'Hare, Thomas, Tyner, Jeffrey W., Loriaux, Marc, Goss, Valerie L., Lee, Kimberly A., Eide, Christopher A., Wong, Matthew J., Stoffregen, Eric P., McGreevey, Laura, Nardone, Julie, Moore, Sandra A., Crispino, John, Boggon, Titus J., Heinrich, Michael C., Deininger, Michael W., Polakiewicz, Roberto D., Gilliland, D. Gary, Druker, Brian J.

Volltext

Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models von Thiollier, Clarisse, Lopez, Cécile K, Gerby, Bastien, Ignacimouttou, Cathy, Poglio, Sandrine, Duffourd, Yannis, Guégan, Justine, Rivera-Munoz, Paola, Bluteau, Olivier, Mabialah, Vinciane, Diop, M'boyba, Wen, Qiang, Petit, Arnaud, Bauchet, Anne-Laure, Reinhardt, Dirk, Bornhauser, Beat, Gautheret, Daniel, Lecluse, Yann, Landman-Parker, Judith, Radford, Isabelle, Vainchenker, William, Dastugue, Nicole, de Botton, Stéphane, Dessen, Philippe, Bourquin, Jean-Pierre, Crispino, John D, Ballerini, Paola, Bernard, Olivier A, Pflumio, Françoise, Mercher, Thomas

Volltext