The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications von Durcan, Thomas M, Fon, Edward A

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Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy von McLelland, Gian-Luca, Goiran, Thomas, Yi, Wei, Dorval, Geneviève, Chen, Carol X, Lauinger, Nadine D, Krahn, Andrea I, Valimehr, Sepideh, Rakovic, Aleksandar, Rouiller, Isabelle, Durcan, Thomas M, Trempe, Jean-François, Fon, Edward A

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Defending the mitochondria: The pathways of mitophagy and mitochondrial-derived vesicles von Roberts, Rosalind F., Tang, Matthew Y., Fon, Edward A., Durcan, Thomas M.

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The Neglected Genes of ALS: Cytoskeletal Dynamics Impact Synaptic Degeneration in ALS von Castellanos-Montiel, María José, Chaineau, Mathilde, Durcan, Thomas M.

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Loss of C9orf72 perturbs the Ran-GTPase gradient and nucleocytoplasmic transport, generating compositionally diverse Importin β-1 granules von McGoldrick, Philip, Lau, Agnes, You, Zhipeng, Durcan, Thomas M., Robertson, Janice

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Compressive molding of engineered tissues via thermoresponsive hydrogel devices von Cassel de Camps, Camille, Mok, Stephanie, Ashby, Emily, Li, Chen, Lépine, Paula, Durcan, Thomas M, Moraes, Christopher

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Editorial: The next generation of tools and technologies for studying human neurons in a dish von Durcan, Thomas M, Axtman, Alison D

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An Inducible Luminescent System to Explore Parkinson's Disease-Associated Genes von Gandy, Anelya, Maussion, Gilles, Al-Habyan, Sara, Nicouleau, Michael, You, Zhipeng, Chen, Carol X-Q, Abdian, Narges, Aprahamian, Nathalia, Krahn, Andrea I, Larocque, Louise, Durcan, Thomas M, Deneault, Eric

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Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72 von Laflamme, Carl, McKeever, Paul M, Kumar, Rahul, Schwartz, Julie, Kolahdouzan, Mahshad, Chen, Carol X, You, Zhipeng, Benaliouad, Faiza, Gileadi, Opher, McBride, Heidi M, Durcan, Thomas M, Edwards, Aled M, Healy, Luke M, Robertson, Janice, McPherson, Peter S

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The 37TrillionCells initiative for improving global healthcare via cell-based interception and precision medicine: focus on neurodegenerative diseases von Coulombe, Benoit, Durcan, Thomas M, Bernard, Geneviève, Moursli, Asmae, Poitras, Christian, Faubert, Denis, Pinard, Maxime

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The Machado―Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability von DURCAN, Thomas M, KONTOGIANNEA, Maria, THORARINSDOTTIR, Thorhildur, FALLON, Lara, WILLIAMS, Aislinn J, DJARMATI, Ana, FANTANEANU, Tadeu, PAULSON, Henry L, FON, Edward A

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Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications von Ayoubi, Riham, Ryan, Joel, Biddle, Michael S, Alshafie, Walaa, Fotouhi, Maryam, Bolivar, Sara Gonzalez, Ruiz Moleon, Vera, Eckmann, Peter, Worrall, Donovan, McDowell, Ian, Southern, Kathleen, Reintsch, Wolfgang, Durcan, Thomas M, Brown, Claire, Bandrowski, Anita, Virk, Harvinder, Edwards, Aled M, McPherson, Peter, Laflamme, Carl

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Auto-qPCR; a python-based web app for automated and reproducible analysis of qPCR data von Maussion, Gilles, Thomas, Rhalena A., Demirova, Iveta, Gu, Gracia, Cai, Eddie, Chen, Carol X.-Q., Abdian, Narges, Strauss, Theodore J. P., Kelaï, Sabah, Nauleau-Javaudin, Angela, Beitel, Lenore K., Ramoz, Nicolas, Gorwood, Philip, Durcan, Thomas M.

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Combining NGN2 programming and dopaminergic patterning for a rapid and efficient generation of hiPSC-derived midbrain neurons von Sheta, Razan, Teixeira, Maxime, Idi, Walid, Pierre, Marion, de Rus Jacquet, Aurelie, Emond, Vincent, Zorca, Cornelia E., Vanderperre, Benoît, Durcan, Thomas M., Fon, Edward A., Calon, Frédéric, Chahine, Mohamed, Oueslati, Abid

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A Multistep Workflow to Evaluate Newly Generated iPSCs and Their Ability to Generate Different Cell Types von Chen, Carol X.-Q., Abdian, Narges, Maussion, Gilles, Thomas, Rhalena A., Demirova, Iveta, Cai, Eddie, Tabatabaei, Mahdieh, Beitel, Lenore K., Karamchandani, Jason, Fon, Edward A., Durcan, Thomas M.

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Generation of human iPSC-derived phrenic-like motor neurons to model respiratory motor neuron degeneration in ALS von Thiry, Louise, Sirois, Julien, Durcan, Thomas M., Stifani, Stefano

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Defining the Neural Kinome: Strategies and Opportunities for Small Molecule Drug Discovery to Target Neurodegenerative Diseases von Krahn, Andrea I, Wells, Carrow, Drewry, David H, Beitel, Lenore K, Durcan, Thomas M, Axtman, Alison D

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An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids von Castellanos-Montiel, María José, Chaineau, Mathilde, Franco-Flores, Anna Kristyna, Haghi, Ghazal, Carrillo-Valenzuela, Dulce, Reintsch, Wolfgang E, Chen, Carol X-Q, Durcan, Thomas M

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Disruption of GRIN2B Impairs Differentiation in Human Neurons von Bell, Scott, Maussion, Gilles, Jefri, Malvin, Peng, Huashan, Theroux, Jean-Francois, Silveira, Heika, Soubannier, Vincent, Wu, Hanrong, Hu, Peng, Galat, Ekaterina, Torres-Platas, S. Gabriela, Boudreau-Pinsonneault, Camille, O'Leary, Liam A., Galat, Vasiliy, Turecki, Gustavo, Durcan, Thomas M., Fon, Edward A., Mechawar, Naguib, Ernst, Carl

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Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria von Vranas, Marta, Lu, Yang, Rasool, Shafqat, Croteau, Nathalie, Krett, Jonathan D, Sauvé, Véronique, Gehring, Kalle, Fon, Edward A, Durcan, Thomas M, Trempe, Jean-François

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