Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel von Döhner, Hartmut, Estey, Elihu, Grimwade, David, Amadori, Sergio, Appelbaum, Frederick R., Büchner, Thomas, Dombret, Hervé, Ebert, Benjamin L., Fenaux, Pierre, Larson, Richard A., Levine, Ross L., Lo-Coco, Francesco, Naoe, Tomoki, Niederwieser, Dietger, Ossenkoppele, Gert J., Sanz, Miguel, Sierra, Jorge, Tallman, Martin S., Tien, Hwei-Fang, Wei, Andrew H., Löwenberg, Bob, Bloomfield, Clara D.

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Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet von Döhner, Hartmut, Estey, Elihu H., Amadori, Sergio, Appelbaum, Frederick R., Büchner, Thomas, Burnett, Alan K., Dombret, Hervé, Fenaux, Pierre, Grimwade, David, Larson, Richard A., Lo-Coco, Francesco, Naoe, Tomoki, Niederwieser, Dietger, Ossenkoppele, Gert J., Sanz, Miguel A., Sierra, Jorge, Tallman, Martin S., Löwenberg, Bob, Bloomfield, Clara D.

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Management of acute promyelocytic leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet von Sanz, Miguel A., Grimwade, David, Tallman, Martin S., Lowenberg, Bob, Fenaux, Pierre, Estey, Elihu H., Naoe, Tomoki, Lengfelder, Eva, Büchner, Thomas, Döhner, Hartmut, Burnett, Alan K., Lo-Coco, Francesco

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Allogeneic Transplantation Versus Chemotherapy as Postremission Therapy for Acute Myeloid Leukemia: A Prospective Matched Pairs Analysis von STELLJES, Matthias, KRUG, Utz, BERNING, Björna, KOLB, Hans J, REICHLE, Albrecht, HOLLER, Ernst, SCHWERDTFEGER, Rainer, ARNOLD, Renate, SCHEID, Christoph, MÜLLER-TIDOW, Carsten, WOERMANN, Bernhard J, HIDDEMANN, Wolfgang, BEELEN, Dietrich W, BERDEL, Wolfgang E, BÜCHNER, Thomas, BRAESS, Jan, SAUERLAND, Maria C, HEINECKE, Achim, LIGGES, Sandra, SAUER, Tim, TSCHANTER, Petra, THOENNISSEN, Gabriela B

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An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia von Metzeler, Klaus H., Hummel, Manuela, Bloomfield, Clara D., Spiekermann, Karsten, Braess, Jan, Sauerland, Maria-Cristina, Heinecke, Achim, Radmacher, Michael, Marcucci, Guido, Whitman, Susan P., Maharry, Kati, Paschka, Peter, Larson, Richard A., Berdel, Wolfgang E., Büchner, Thomas, Wörmann, Bernhard, Mansmann, Ulrich, Hiddemann, Wolfgang, Bohlander, Stefan K., Buske, Christian

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Identification of a 24-Gene Prognostic Signature That Improves the European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: An International Collaborative Study von Li, Zejuan, Herold, Tobias, He, Chunjiang, Valk, Peter J M, Chen, Ping, Jurinovic, Vindi, Mansmann, Ulrich, Radmacher, Michael D, Maharry, Kati S, Sun, Miao, Yang, Xinan, Huang, Hao, Jiang, Xi, Sauerland, Maria-Cristina, Büchner, Thomas, Hiddemann, Wolfgang, Elkahloun, Abdel, Neilly, Mary Beth, Zhang, Yanming, Larson, Richard A, Le Beau, Michelle M, Caligiuri, Michael A, Döhner, Konstanze, Bullinger, Lars, Liu, Paul P, Delwel, Ruud, Marcucci, Guido, Lowenberg, Bob, Bloomfield, Clara D, Rowley, Janet D, Bohlander, Stefan K, Chen, Jianjun

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Acute Myeloid Leukemia With Biallelic CEBPA Gene Mutations and Normal Karyotype Represents a Distinct Genetic Entity Associated With a Favorable Clinical Outcome von DUFOUR, Annika, SCHNEIDER, Friederike, WÖRMANN, Bernhard, BRAESS, Jan, HIDDEMANN, Wolfgang, BOHLANDER, Stefan K, SPIEKERMANN, Karsten, METZELER, Klaus H, HOSTER, Eva, SCHNEIDER, Stephanie, ZELLMEIER, Evelyn, BENTHAUS, Tobias, SAUERLAND, Maria-Cristina, BERDEL, Wolfgang E, BÜCHNER, Thomas

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Age-Related Risk Profile and Chemotherapy Dose Response in Acute Myeloid Leukemia: A Study by the German Acute Myeloid Leukemia Cooperative Group von BÜCHNER, Thomas, BERDEL, Wolfgang E, GRIINEISEN, Andreas, KERN, Wolfgang, REICHLE, Albrecht, MASCHMEYER, Georg, AUL, Carlo, LENGFELDER, Eva, SAUERLAND, Maria-Cristina, HEINECKE, Achim, WÖRMANN, Bernhard, HIDDEMANN, Wolfgang, HAFERLACH, Claudia, HAFERLACH, Torsten, SCHNITTGER, Susanne, MÜLLER-TIDOW, Carsten, BRAESS, Jan, SPIEKERMANN, Karsten, KIENAST, Joachim, STAIB, Peter

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Early blast clearance by remission induction therapy is a major independent prognostic factor for both achievement of complete remission and long-term outcome in acute myeloid leuk... von Kern, Wolfgang, Haferlach, Torsten, Schoch, Claudia, Löffler, Helmut, Gassmann, Winfried, Heinecke, Achim, Sauerland, Maria Christina, Berdel, Wolfgang, Büchner, Thomas, Hiddemann, Wolfgang

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Acute Myeloid Leukemia (AML): Different Treatment Strategies Versus a Common Standard Arm—Combined Prospective Analysis by the German AML Intergroup von BÜCHNER, Thomas, SCHLENK, Richard F, SPÄTH, Daniela, KRAMER, Michael, SCHOLL, Sebastian, BERDEL, Wolfgang E, HIDDEMANN, Wolfgang, HOELZER, Dieter, HEHLMANN, Rüdiger, HASFORD, Joerg, HOFFMANN, Verena S, DÖHNER, Hartmut, SCHAICH, Markus, EHNINGER, Gerhard, GANSER, Arnold, NIEDERWIESER, Dietger W, PFIRRMANN, Markus, DÖHNER, Konstanze, KRAHL, Rainer, KRAUTER, Jürgen, HEIL, Gerhard, KRUG, Utz, SAUERLAND, Maria Cristina, HEINECKE, Achim

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Activating FLT3 mutants show distinct gain-of-function phenotypes in vitro and a characteristic signaling pathway profile associated with prognosis in acute myeloid leukemia von Janke, Hanna, Pastore, Friederike, Schumacher, Daniela, Herold, Tobias, Hopfner, Karl-Peter, Schneider, Stephanie, Berdel, Wolfgang E, Büchner, Thomas, Woermann, Bernhard J, Subklewe, Marion, Bohlander, Stefan K, Hiddemann, Wolfgang, Spiekermann, Karsten, Polzer, Harald

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Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis von Herold, Tobias, Metzeler, Klaus H., Vosberg, Sebastian, Hartmann, Luise, Röllig, Christoph, Stölzel, Friedrich, Schneider, Stephanie, Hubmann, Max, Zellmeier, Evelyn, Ksienzyk, Bianka, Jurinovic, Vindi, Pasalic, Zlatana, Kakadia, Purvi M., Dufour, Annika, Graf, Alexander, Krebs, Stefan, Blum, Helmut, Sauerland, Maria Cristina, Büchner, Thomas, Berdel, Wolfgang E., Woermann, Bernhard J., Bornhäuser, Martin, Ehninger, Gerhard, Mansmann, Ulrich, Hiddemann, Wolfgang, Bohlander, Stefan K., Spiekermann, Karsten, Greif, Philipp A.

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ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation von Hartmann, Luise, Dutta, Sayantanee, Opatz, Sabrina, Vosberg, Sebastian, Reiter, Katrin, Leubolt, Georg, Metzeler, Klaus H., Herold, Tobias, Bamopoulos, Stefanos A., Bräundl, Kathrin, Zellmeier, Evelyn, Ksienzyk, Bianka, Konstandin, Nikola P., Schneider, Stephanie, Hopfner, Karl-Peter, Graf, Alexander, Krebs, Stefan, Blum, Helmut, Middeke, Jan Moritz, Stölzel, Friedrich, Thiede, Christian, Wolf, Stephan, Bohlander, Stefan K., Preiss, Caroline, Chen-Wichmann, Linping, Wichmann, Christian, Sauerland, Maria Cristina, Büchner, Thomas, Berdel, Wolfgang E., Wörmann, Bernhard J., Braess, Jan, Hiddemann, Wolfgang, Spiekermann, Karsten, Greif, Philipp A.

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Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marke... von Schnittger, Susanne, Schoch, Claudia, Dugas, Martin, Kern, Wolfgang, Staib, Peter, Wuchter, Christian, Löffler, Helmut, Sauerland, Cristina Maria, Serve, Hubert, Büchner, Thomas, Haferlach, Torsten, Hiddemann, Wolfgang

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Revised Recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials i... von CHESON, Bruce D, BENNETT, John M, LOCOCCO, Francesco, WILLEMZE, Roel, BIONDI, Andrea, HIDDEMANN, Wolfgang, LARSON, Richard A, LÖWENBERG, Bob, SANZ, Miguel A, HEAD, David R, OHNO, Ryuzo, BLOOMFIELD, Clara D, KOPECKY, Kenneth J, BÜCHNER, Thomas, WILLMAN, Cheryl L, ESTEY, Elihu H, SCHIFFER, Charles A, DOEHNER, Hartmut, TALLMAN, Martin S, LISTER, T. Andrew

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DNA methylation of tumor suppressor genes in clinical remission predicts the relapse risk in acute myeloid leukemia von AGRAWAL, Shuchi, UNTERBERG, Matthias, KOSCHMIEDER, Steffen, UDO ZUR STADT, BRUNNBERG, Uta, VERBEEK, Walter, BÜCHNER, Thomas, BERDEL, Wolfgang E, SERVE, Hubert, MÜLLER-TIDOW, Carsten

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ERG Expression Is an Independent Prognostic Factor and Allows Refined Risk Stratification in Cytogenetically Normal Acute Myeloid Leukemia: A Comprehensive Analysis of ERG, MN1, an... von METZELER, Klaus H, DUFOUR, Annika, BRAESS, Jan, SPIEKERMANN, Karsten, HIDDEMANN, Wolfgang, BUSKE, Christian, BOHLANDER, Stefan K, BENTHAUS, Tobias, HUMMEL, Manuela, SAUERLAND, Maria-Cristina, HEINECKE, Achim, BERDEL, Wolfgang E, BÜCHNER, Thomas, WÖRMANN, Bernhard, MANSMANN, Ulrich

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Significance of age in acute myeloid leukemia patients younger than 30 years von Creutzig, Ursula, Büchner, Thomas, Sauerland, Maria C., Zimmermann, Martin, Reinhardt, Dirk, Döhner, Hartmut, Schlenk, Richard F.

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Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia von Metzeler, Klaus H., Herold, Tobias, Rothenberg-Thurley, Maja, Amler, Susanne, Sauerland, Maria C., Görlich, Dennis, Schneider, Stephanie, Konstandin, Nikola P., Dufour, Annika, Bräundl, Kathrin, Ksienzyk, Bianka, Zellmeier, Evelyn, Hartmann, Luise, Greif, Philipp A., Fiegl, Michael, Subklewe, Marion, Bohlander, Stefan K., Krug, Utz, Faldum, Andreas, Berdel, Wolfgang E., Wörmann, Bernhard, Büchner, Thomas, Hiddemann, Wolfgang, Braess, Jan, Spiekermann, Karsten

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Osteopontin is a prognostic factor for survival of acute myeloid leukemia patients von Liersch, Ruediger, Gerss, Joachim, Schliemann, Christoph, Bayer, Michael, Schwöppe, Christian, Biermann, Christoph, Appelmann, Iris, Kessler, Torsten, Löwenberg, Bob, Büchner, Thomas, Hiddemann, Wolfgang, Müller-Tidow, Carsten, Berdel, Wolfgang E., Mesters, Rolf

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