Three decades of advancements in osteoarthritis research: insights from transcriptomic, proteomic, and metabolomic studies von Rai, Muhammad Farooq, Collins, Kelsey H., Lang, Annemarie, Maerz, Tristan, Geurts, Jeroen, Ruiz-Romero, Cristina, June, Ronald K., Ramos, Yolande, Rice, Sarah J., Ali, Shabana Amanda, Pastrello, Chiara, Jurisica, Igor, Thomas Appleton, C., Rockel, Jason S., Kapoor, Mohit

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Evolution and advancements in genomics and epigenomics in OA research: How far we have come von Ramos, Yolande F.M., Rice, Sarah J., Ali, Shabana Amanda, Pastrello, Chiara, Jurisica, Igor, Rai, Muhammad Farooq, Collins, Kelsey H., Lang, Annemarie, Maerz, Tristan, Geurts, Jeroen, Ruiz-Romero, Cristina, June, Ronald K., Thomas Appleton, C., Rockel, Jason S., Kapoor, Mohit

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Human osteoarthritis knee joint synovial fluids cleave and activate Proteinase-Activated Receptor (PAR) mediated signaling von Chandrabalan, Arundhasa, Firth, Andrew, Litchfield, Robert B., Appleton, C. Thomas, Getgood, Alan, Ramachandran, Rithwik

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Brentuximab vedotin for skin involvement in refractory diffuse cutaneous systemic sclerosis, an open-label trial von Fernández-Codina, Andreu, Nevskaya, Tatiana, Baron, Murray, Thomas Appleton, C, Cecchini, Matthew J, Philip, Amanda, El-Shimy, Maha, Vanderhoek, Louise, Pinal-Fernández, Iago, Pope, Janet E

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Changes and associations between synovial fluid and magnetic resonance imaging markers of osteoarthritis after high tibial osteotomy von Schulz, Jenna M, Birmingham, Trevor B, Philpott, Holly T, Appleton, C Thomas, Atkinson, Hayden F, Giffin, J Robert, Beier, Frank

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Targeting STAT6-mediated synovial macrophage activation improves pain in experimental knee osteoarthritis von Blackler, Garth, Lai-Zhao, Yue, Klapak, Joseph, Philpott, Holly T, Pitchers, Kyle K, Maher, Andrew R, Fiset, Benoit, Walsh, Logan A, Gillies, Elizabeth R, Appleton, C Thomas

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Tensile strain and altered synovial tissue metabolism in human knee osteoarthritis von Philpott, Holly T., Birmingham, Trevor B., Fiset, Benoit, Walsh, Logan A., Coleman, Mitchell C., Séguin, Cheryle A., Appleton, C. Thomas

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Rho/ROCK and MEK/ERK activation by transforming growth factor-α induces articular cartilage degradation von Appleton, C Thomas G, Usmani, Shirine E, Mort, John S, Beier, Frank

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ADAMTS-7 forms a positive feedback loop with TNF-α in the pathogenesis of osteoarthritis von Lai, Yongjie, Bai, Xiaohui, Zhao, Yunpeng, Tian, Qingyun, Liu, Ben, Lin, Edward A, Chen, Yuqing, Lee, Brendan, Appleton, C Thomas, Beier, Frank, Yu, Xiu-Ping, Liu, Chuan-ju

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Sex-Differences and Associations Between Complement Activation and Synovial Vascularization in Patients with Late-Stage Knee Osteoarthritis von Sodhi, Emily U, Philpott, Holly T, Carter, McKenzie M, Birmingham, Trevor B, Appleton, C Thomas

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Assessment of Surrogate Markers for Cardiovascular Disease in Familial Mediterranean Fever-Related Amyloidosis Patients Homozygous for M694V Mutation in MEFV Gene von Sahin, Sezgin, Romano, Micol, Guzel, Ferhat, Piskin, David, Poddighe, Dimitri, Sezer, Siren, Kasapcopur, Ozgur, Appleton, C Thomas, Yilmaz, Ilker, Demirkaya, Erkan

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Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis von Appleton, C Thomas G, McErlain, David D, Pitelka, Vasek, Schwartz, Neil, Bernier, Suzanne M, Henry, James L, Holdsworth, David W, Beier, Frank

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The Pattern Recognition Receptor CD36 Is a Chondrocyte Hypertrophy Marker Associated with Suppression of Catabolic Responses and Promotion of Repair Responses to Inflammatory Stimu... von Cecil, Denise L, Appleton, C. Thomas G, Polewski, Monika D, Mort, John S, Schmidt, Ann Marie, Bendele, Alison, Beier, Frank, Terkeltaub, Robert

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Microarray analyses of gene expression during chondrocyte differentiation identifies novel regulators of hypertrophy von James, Claudine G, Appleton, C Thomas G, Ulici, Veronica, Underhill, T Michael, Beier, Frank

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Response to letter to the editor regarding ‘Association between synovial tissue damage and pain in late-stage knee osteoarthritis: A cross-sectional study’ von Philpott, Holly T., Birmingham, Trevor B., Appleton, C. Thomas

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Attenuation correction for PET/MRI to measure tracer activity surrounding total knee arthroplasty von Bourdon, Caleigh E., Koudys, Zachary J., Lanting, Brent A., Appleton, C. Thomas, Thiessen, Jonathan D., Teeter, Matthew G.

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Impaired Efferocytosis by Synovial Macrophages in Patients With Knee Osteoarthritis von Del Sordo, Luigi, Blackler, Garth B., Philpott, Holly T., Riviere, Jared, Gunaratnam, Lakshman, Heit, Bryan, Appleton, C. Thomas

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F-spondin, a neuroregulatory protein, is up-regulated in osteoarthritis and regulates cartilage metabolism via TGF-β activation von Attur, Mukundan G, Palmer, Glyn D, Al-Mussawir, Hayf E, Dave, Mandar, Teixeira, Cristina C, Rifkin, Daniel B, Appleton, C. Thomas G, Beier, Frank, Abramson, Steven B

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A scoping review of how early-stage knee osteoarthritis has been defined von Liew, Jean W., King, Lauren K., Mahmoudian, Armaghan, Wang, Qiuke, Atkinson, Hayden F., Flynn, David B., Appleton, C. Thomas, Englund, Martin, Haugen, Ida K., Lohmander, L. Stefan, Runhaar, Jos, Neogi, Tuhina, Hawker, Gillian

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Preventing Cardiovascular Events in Patients With Inflammatory Arthritis: Are We Missing the Mark? von Appleton, C. Thomas, Hegele, Robert A.

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