Abstract W P74: The Effects of Hypertension and Hypotension on Patient-Specific Computer Modeled Clipping of an ICA Aneurysm von Riccardello, Gerald J, Changa, Abhinav R, Thomas, Kiran G, Roman, Max, Barr, Luke K, Lott, Dawn A, Singh, Paul, Gandhi, Chirag D, Prestigiacomo, Charles J

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Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis von Ettehad, Dena, MSc, Emdin, Connor A, HBSc, Kiran, Amit, PhD, Anderson, Simon G, PhD, Callender, Thomas, MB ChB, Emberson, Jonathan, PhD, Chalmers, John, Prof, Rodgers, Anthony, Prof, Rahimi, Kazem, Prof

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Optimization and characterization of a new lipopeptide biosurfactant produced by marine Brevibacterium aureum MSA13 in solid state culture von Seghal Kiran, G., Anto Thomas, T., Selvin, Joseph, Sabarathnam, B., Lipton, A.P.

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Subclinical deformities of the hip are significant predictors of radiographic osteoarthritis and joint replacement in women. A 20 year longitudinal cohort study von Thomas, G.E.R, Palmer, A.J.R, Batra, R.N, Kiran, A, Hart, D, Spector, T, Javaid, M.K, Judge, A, Murray, D.W, Carr, A.J, Arden, N.K, Glyn-Jones, S

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Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes von Shah, Parisha P., Lv, Wenjian, Rhoades, Joshua H., Poleshko, Andrey, Abbey, Deepti, Caporizzo, Matthew A., Linares-Saldana, Ricardo, Heffler, Julie G., Sayed, Nazish, Thomas, Dilip, Wang, Qiaohong, Stanton, Liam J., Bedi, Kenneth, Morley, Michael P., Cappola, Thomas P., Owens, Anjali T., Margulies, Kenneth B., Frank, David B., Wu, Joseph C., Rader, Daniel J., Yang, Wenli, Prosser, Benjamin L., Musunuru, Kiran, Jain, Rajan

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Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets von Baldauf, Michaela C, Orth, Martin F, Dallmayer, Marlene, Marchetto, Aruna, Gerke, Julia S, Rubio, Rebeca Alba, Kiran, Merve M, Musa, Julian, Knott, Maximilian M L, Ohmura, Shunya, Li, Jing, Akpolat, Nusret, Akatli, Ayse N, Özen, Özlem, Dirksen, Uta, Hartmann, Wolfgang, de Alava, Enrique, Baumhoer, Daniel, Sannino, Giuseppina, Kirchner, Thomas, Grünewald, Thomas G P

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In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates von Musunuru, Kiran, Chadwick, Alexandra C., Mizoguchi, Taiji, Garcia, Sara P., DeNizio, Jamie E., Reiss, Caroline W., Wang, Kui, Iyer, Sowmya, Dutta, Chaitali, Clendaniel, Victoria, Amaonye, Michael, Beach, Aaron, Berth, Kathleen, Biswas, Souvik, Braun, Maurine C., Chen, Huei-Mei, Colace, Thomas V., Ganey, John D., Gangopadhyay, Soumyashree A., Garrity, Ryan, Kasiewicz, Lisa N., Lavoie, Jennifer, Madsen, James A., Matsumoto, Yuri, Mazzola, Anne Marie, Nasrullah, Yusuf S., Nneji, Joseph, Ren, Huilan, Sanjeev, Athul, Shay, Madeleine, Stahley, Mary R., Fan, Steven H. Y., Tam, Ying K., Gaudelli, Nicole M., Ciaramella, Giuseppe, Stolz, Leslie E., Malyala, Padma, Cheng, Christopher J., Rajeev, Kallanthottathil G., Rohde, Ellen, Bellinger, Andrew M., Kathiresan, Sekar

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Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection von Pardiñas, Antonio F., Holmans, Peter, Pocklington, Andrew J., Escott-Price, Valentina, Ripke, Stephan, Carrera, Noa, Legge, Sophie E., Bishop, Sophie, Cameron, Darren, Hamshere, Marian L., Han, Jun, Hubbard, Leon, Lynham, Amy, Mantripragada, Kiran, Rees, Elliott, MacCabe, James H., McCarroll, Steven A., Baune, Bernhard T., Breen, Gerome, Byrne, Enda M., Dannlowski, Udo, Eley, Thalia C., Hayward, Caroline, Martin, Nicholas G., McIntosh, Andrew M., Plomin, Robert, Porteous, David J., Wray, Naomi R., Caballero, Armando, Geschwind, Daniel H., Huckins, Laura M., Ruderfer, Douglas M., Santiago, Enrique, Sklar, Pamela, Stahl, Eli A., Won, Hyejung, Agerbo, Esben, Als, Thomas D., Andreassen, Ole A., Bækvad-Hansen, Marie, Mortensen, Preben Bo, Pedersen, Carsten Bøcker, Børglum, Anders D., Bybjerg-Grauholm, Jonas, Djurovic, Srdjan, Durmishi, Naser, Pedersen, Marianne Giørtz, Golimbet, Vera, Grove, Jakob, Hougaard, David M., Mattheisen, Manuel, Molden, Espen, Mors, Ole, Nordentoft, Merete, Pejovic-Milovancevic, Milica, Sigurdsson, Engilbert, Silagadze, Teimuraz, Hansen, Christine Søholm, Stefansson, Kari, Stefansson, Hreinn, Steinberg, Stacy, Tosato, Sarah, Werge, Thomas, Collier, David A., Rujescu, Dan, Kirov, George, Owen, Michael J., O’Donovan, Michael C., Walters, James T. R.

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Age-associated B cells predict impaired humoral immunity after COVID-19 vaccination in patients receiving immune checkpoint blockade von Yam-Puc, Juan Carlos, Hosseini, Zhaleh, Horner, Emily C., Gerber, Pehuén Pereyra, Beristain-Covarrubias, Nonantzin, Hughes, Robert, Lulla, Aleksei, Rust, Maria, Boston, Rebecca, Ali, Magda, Fischer, Katrin, Simmons-Rosello, Edward, O’Reilly, Martin, Robson, Harry, Booth, Lucy H., Kahanawita, Lakmini, Correa-Noguera, Andrea, Favara, David, Ceron-Gutierrez, Lourdes, Keller, Baerbel, Craxton, Andrew, Anderson, Georgina S. F., Sun, Xiao-Ming, Elmer, Anne, Saunders, Caroline, Bermperi, Areti, Jose, Sherly, Kingston, Nathalie, Mulroney, Thomas E., Piñon, Lucia P. G., Chapman, Michael A., Grigoriadou, Sofia, MacFarlane, Marion, Willis, Anne E., Patil, Kiran R., Spencer, Sarah, Staples, Emily, Warnatz, Klaus, Buckland, Matthew S., Hollfelder, Florian, Hyvönen, Marko, Döffinger, Rainer, Parkinson, Christine, Lear, Sara, Matheson, Nicholas J., Thaventhiran, James E. D.

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Diagnosis, management, and treatment of hepatitis C: An update von Ghany, Marc G., Strader, Doris B., Thomas, David L., Seeff, Leonard B.

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Production of a new glycolipid biosurfactant from marine Nocardiopsis lucentensis MSA04 in solid-state cultivation von Kiran, G. Seghal, Thomas, T. Anto, Selvin, Joseph

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Tailored for Real-World: A Whole Slide Image Classification System Validated on Uncurated Multi-Site Data Emulating the Prospective Pathology Workload von Ianni, Julianna D., Soans, Rajath E., Sankarapandian, Sivaramakrishnan, Chamarthi, Ramachandra Vikas, Ayyagari, Devi, Olsen, Thomas G., Bonham, Michael J., Stavish, Coleman C., Motaparthi, Kiran, Cockerell, Clay J., Feeser, Theresa A., Lee, Jason B.

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Systematic identification of cancer-specific MHC-binding peptides with RAVEN von Baldauf, Michaela C., Gerke, Julia S., Kirschner, Andreas, Blaeschke, Franziska, Effenberger, Manuel, Schober, Kilian, Rubio, Rebeca Alba, Kanaseki, Takayuki, Kiran, Merve M., Dallmayer, Marlene, Musa, Julian, Akpolat, Nurset, Akatli, Ayse N., Rosman, Fernando C., Özen, Özlem, Sugita, Shintaro, Hasegawa, Tadashi, Sugimura, Haruhiko, Baumhoer, Daniel, Knott, Maximilian M. L., Sannino, Giuseppina, Marchetto, Aruna, Li, Jing, Busch, Dirk H., Feuchtinger, Tobias, Ohmura, Shunya, Orth, Martin F., Thiel, Uwe, Kirchner, Thomas, Grünewald, Thomas G. P.

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Reactive oxygen species as an independent marker of male factor infertility von Agarwal, Ashok, Sharma, Rakesh K., Nallella, Kiran P., Thomas, Anthony J., Alvarez, Juan G., Sikka, Suresh C.

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Insights into the Mechanism of Paraoxonase-1: Comparing the Reactivity of the Six-Bladed β‑Propeller Hydrolases von Grunkemeyer, Timothy J., Mata, David G., Doddapaneni, Kiran, Murali, Srividya, Magliery, Thomas J.

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Assessment of Heart Transplant Waitlist Time and Pre- and Post-transplant Failure: A Mixed Methods Approach von Goldstein, Benjamin A., Thomas, Laine, Zaroff, Jonathan G., Nguyen, John, Menza, Rebecca, Khush, Kiran K.

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Mechanistic insights into volatile anesthetic modulation of K2P channels von Wague, Aboubacar, Joseph, Thomas T, Woll, Kellie A, Bu, Weiming, Vaidya, Kiran A, Bhanu, Natarajan V, Garcia, Benjamin A, Nimigean, Crina M, Eckenhoff, Roderic G, Riegelhaupt, Paul M

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Optimization, Purification, and Characterization of Extracellular Mesophilic Alkaline Cellulase from Sponge-Associated Marinobacter sp. MSI032 von Shanmughapriya, S, Kiran, G. Seghal, Selvin, Joseph, Thomas, T. Anto, Rani, C

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Optimization and production of a biosurfactant from the sponge-associated marine fungus Aspergillus ustus MSF3 von Kiran, G. Seghal, Hema, T.A., Gandhimathi, R., Selvin, Joseph, Thomas, T. Anto, Rajeetha Ravji, T., Natarajaseenivasan, K.

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The MedSafer Study—Electronic Decision Support for Deprescribing in Hospitalized Older Adults: A Cluster Randomized Clinical Trial von McDonald, Emily G, Wu, Peter E, Rashidi, Babak, Wilson, Marnie Goodwin, Bortolussi-Courval, Émilie, Atique, Anika, Battu, Kiran, Bonnici, Andre, Elsayed, Sarah, Wilson, Allison Goodwin, Papillon-Ferland, Louise, Pilote, Louise, Porter, Sandra, Murphy, Johanna, Ross, Sydney B, Shiu, Jennifer, Tamblyn, Robyn, Whitty, Rachel, Xu, Jieqing, Fabreau, Gabriel, Haddad, Taleen, Palepu, Anita, Khan, Nadia, McAlister, Finlay A, Downar, James, Huang, Allen R, MacMillan, Thomas E, Cavalcanti, Rodrigo B, Lee, Todd C

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