Meningiomas: knowledge base, treatment outcomes, and uncertainties. A RANO review von Rogers, Leland, Barani, Igor, Chamberlain, Marc, Kaley, Thomas J, McDermott, Michael, Raizer, Jeffrey, Schiff, David, Weber, Damien C, Wen, Patrick Y, Vogelbaum, Michael A

Volltext

Phase 1b trial of an ibrutinib-based combination therapy in recurrent/refractory CNS lymphoma von Grommes, Christian, Tang, Sarah S., Wolfe, Julia, Kaley, Thomas J., Daras, Mariza, Pentsova, Elena I., Piotrowski, Anna F., Stone, Jacqueline, Lin, Andrew, Nolan, Craig P., Manne, Malbora, Codega, Paolo, Campos, Carl, Viale, Agnes, Thomas, Alissa A., Berger, Michael F., Hatzoglou, Vaios, Reiner, Anne S., Panageas, Katherine S., DeAngelis, Lisa M., Mellinghoff, Ingo K.

Volltext

Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma von Cloughesy, Timothy F., Mochizuki, Aaron Y., Orpilla, Joey R., Hugo, Willy, Lee, Alexander H., Davidson, Tom B., Wang, Anthony C., Ellingson, Benjamin M., Rytlewski, Julie A., Sanders, Catherine M., Kawaguchi, Eric S., Du, Lin, Li, Gang, Yong, William H., Gaffey, Sarah C., Cohen, Adam L., Mellinghoff, Ingo K., Lee, Eudocia Q., Reardon, David A., O’Brien, Barbara J., Butowski, Nicholas A., Nghiemphu, Phioanh L., Clarke, Jennifer L., Arrillaga-Romany, Isabel C., Colman, Howard, Kaley, Thomas J., de Groot, John F., Liau, Linda M., Wen, Patrick Y., Prins, Robert M.

Volltext

Phase II trial of sunitinib for recurrent and progressive atypical and anaplastic meningioma von Kaley, Thomas J, Wen, Patrick, Schiff, David, Ligon, Keith, Haidar, Sam, Karimi, Sasan, Lassman, Andrew B, Nolan, Craig P, DeAngelis, Lisa M, Gavrilovic, Igor, Norden, Andrew, Drappatz, Jan, Lee, Eudocia Quant, Purow, Benjamin, Plotkin, Scott R, Batchelor, Tracy, Abrey, Lauren E, Omuro, Antonio

Volltext

Therapy of chemotherapy‐induced peripheral neuropathy von Kaley, Thomas J., DeAngelis, Lisa M.

Volltext

R-MPV followed by high-dose chemotherapy with TBC and autologous stem-cell transplant for newly diagnosed primary CNS lymphoma von Omuro, Antonio, Correa, Denise D., DeAngelis, Lisa M., Moskowitz, Craig H., Matasar, Matthew J., Kaley, Thomas J., Gavrilovic, Igor T., Nolan, Craig, Pentsova, Elena, Grommes, Christian C., Panageas, Katherine S., Baser, Raymond E., Faivre, Geraldine, Abrey, Lauren E., Sauter, Craig S.

Volltext

Dynamic contrast enhanced T1 MRI perfusion differentiates pseudoprogression from recurrent glioblastoma von Thomas, Alissa A., Arevalo-Perez, Julio, Kaley, Thomas, Lyo, John, Peck, Kyung K., Shi, Weiji, Zhang, Zhigang, Young, Robert J.

Volltext

Durable complete response in a patient with leptomeningeal melanoma after treatment with dabrafenib, trametinib, and nivolumab von Lochrin, Sarah E., Buonocore, Darren J., Young, Robert J., Kaley, Thomas J., Postow, Michael A., Wolchok, Jedd D., Shoushtari, Alexander N., Momtaz, Parisa, Betof Warner, Allison S., Callahan, Margaret K.

Volltext

Integration of 2-hydroxyglutarate-proton magnetic resonance spectroscopy into clinical practice for disease monitoring in isocitrate dehydrogenase-mutant glioma von de la Fuente, Macarena I, Young, Robert J, Rubel, Jennifer, Rosenblum, Marc, Tisnado, Jamie, Briggs, Samuel, Arevalo-Perez, Julio, Cross, Justin R, Campos, Carl, Straley, Kimberly, Zhu, Dongwei, Dong, Chuanhui, Thomas, Alissa, Omuro, Antonio A, Nolan, Craig P, Pentsova, Elena, Kaley, Thomas J, Oh, Jung H, Noeske, Ralph, Maher, Elizabeth, Choi, Changho, Gutin, Philip H, Holodny, Andrei I, Yen, Katharine, DeAngelis, Lisa M, Mellinghoff, Ingo K, Thakur, Sunitha B

Volltext

EANO - EURACAN - SNO Guidelines on circumscribed astrocytic gliomas, glioneuronal, and neuronal tumors von Rudà, Roberta, Capper, David, Waldman, Adam D, Pallud, Johan, Minniti, Giuseppe, Kaley, Thomas J, Bouffet, Eric, Tabatabai, Ghazaleh, Aronica, Eleonora, Jakola, Asgeir S, Pfister, Stefan M, Schiff, David, Lassman, Andrew B, Solomon, David A, Soffietti, Riccardo, Weller, Michael, Preusser, Matthias, Idbaih, Ahmed, Wen, Patrick Y, van den Bent, Martin J

Volltext

Phase II study of monthly pasireotide LAR (SOM230C) for recurrent or progressive meningioma von Norden, Andrew D, Ligon, Keith L, Hammond, Samantha N, Muzikansky, Alona, Reardon, David A, Kaley, Thomas J, Batchelor, Tracy T, Plotkin, Scott R, Raizer, Jeffrey J, Wong, Eric T, Drappatz, Jan, Lesser, Glenn J, Haidar, Sam, Beroukhim, Rameen, Lee, Eudocia Q, Doherty, Lisa, Lafrankie, Debra, Gaffey, Sarah C, Gerard, Mary, Smith, Katrina H, McCluskey, Christine, Phuphanich, Surasak, Wen, Patrick Y

Volltext

Phase II study of bevacizumab, temozolomide, and hypofractionated stereotactic radiotherapy for newly diagnosed glioblastoma von Omuro, Antonio, Beal, Kathryn, Gutin, Philip, Karimi, Sasan, Correa, Denise D, Kaley, Thomas J, DeAngelis, Lisa M, Chan, Timothy A, Gavrilovic, Igor T, Nolan, Craig, Hormigo, Adilia, Lassman, Andrew B, Mellinghoff, Ingo, Grommes, Christian, Reiner, Anne S, Panageas, Katherine S, Baser, Raymond E, Tabar, Viviane, Pentsova, Elena, Sanchez, Juan, Barradas-Panchal, Renata, Zhang, Jianan, Faivre, Geraldine, Brennan, Cameron W, Abrey, Lauren E, Huse, Jason T

Volltext

Atypical and anaplastic meningiomas treated with bevacizumab von Nayak, Lakshmi, Iwamoto, Fabio M., Rudnick, Jeremy D., Norden, Andrew D., Lee, Eudocia Quant, Drappatz, Jan, Omuro, Antonio, Kaley, Thomas J.

Volltext

Phase II trial of an AKT inhibitor (perifosine) for recurrent glioblastoma von Kaley, Thomas J., Panageas, Katherine S., Mellinghoff, Ingo K., Nolan, Craig, Gavrilovic, Igor T., DeAngelis, Lisa M., Abrey, Lauren E., Holland, Eric C., Lassman, Andrew B.

Volltext

Combination Olaparib and Temozolomide for the Treatment of Glioma: A Retrospective Case Series von Schaff, Lauren R., Kushnirsky, Marina, Lin, Andrew L., Nandakumar, Subhiksha, Grommes, Christian, Miller, Alexandra Michelle, Gavrilovic, Igor T., Nolan, Craig, Pentsova, Elena, Mellinghoff, Ingo K., Kaley, Thomas J.

Volltext

Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma von Grommes, Christian, Pastore, Alessandro, Palaskas, Nicolaos, Tang, Sarah S, Campos, Carl, Schartz, Derrek, Codega, Paolo, Nichol, Donna, Clark, Owen, Hsieh, Wan-Ying, Rohle, Dan, Rosenblum, Marc, Viale, Agnes, Tabar, Viviane S, Brennan, Cameron W, Gavrilovic, Igor T, Kaley, Thomas J, Nolan, Craig P, Omuro, Antonio, Pentsova, Elena, Thomas, Alissa A, Tsyvkin, Elina, Noy, Ariela, Palomba, M Lia, Hamlin, Paul, Sauter, Craig S, Moskowitz, Craig H, Wolfe, Julia, Dogan, Ahmet, Won, Minhee, Glass, Jon, Peak, Scott, Lallana, Enrico C, Hatzoglou, Vaios, Reiner, Anne S, Gutin, Philip H, Huse, Jason T, Panageas, Katherine S, Graeber, Thomas G, Schultz, Nikolaus, DeAngelis, Lisa M, Mellinghoff, Ingo K

Volltext

Inaugural Results of the Individualized Screening Trial of Innovative Glioblastoma Therapy: A Phase II Platform Trial for Newly Diagnosed Glioblastoma Using Bayesian Adaptive Rando... von Rahman, Rifaquat, Trippa, Lorenzo, Lee, Eudocia Q, Arrillaga-Romany, Isabel, Fell, Geoffrey, Touat, Mehdi, McCluskey, Christine, Wiley, Jennifer, Gaffey, Sarah, Drappatz, Jan, Welch, Mary R, Galanis, Evanthia, Ahluwalia, Manmeet S, Colman, Howard, Nabors, L Burt, Hepel, Jaroslaw, Elinzano, Heinrich, Schiff, David, Chukwueke, Ugonma N, Beroukhim, Rameen, Nayak, Lakshmi, McFaline-Figueroa, J Ricardo, Batchelor, Tracy T, Rinne, Mikael L, Kaley, Thomas J, Lu-Emerson, Christine, Mellinghoff, Ingo K, Bi, Wenya Linda, Arnaout, Omar, Peruzzi, Pier Paolo, Haas-Kogan, Daphne, Tanguturi, Shyam, Cagney, Daniel, Aizer, Ayal, Doherty, Lisa, Lavallee, Maria, Fisher-Longden, Brittany, Dowling, Shanna, Geduldig, Jack, Watkinson, Fiona, Pisano, William, Malinowski, Seth, Ramkissoon, Shakti, Santagata, Sandro, Meredith, David M, Chiocca, E Antonio, Reardon, David A, Alexander, Brian M, Ligon, Keith L, Wen, Patrick Y

Volltext

Molecular and Clinical Effects of Notch Inhibition in Glioma Patients: A Phase 0/I Trial von Xu, Ran, Shimizu, Fumiko, Hovinga, Koos, Beal, Kathryn, Karimi, Sasan, Droms, Leif, Peck, Kyung K, Gutin, Philip, Iorgulescu, J Bryan, Kaley, Thomas, DeAngelis, Lisa, Pentsova, Elena, Nolan, Craig, Grommes, Christian, Chan, Timothy, Bobrow, Dylan, Hormigo, Adilia, Cross, Justin R, Wu, Nian, Takebe, Naoko, Panageas, Katherine, Ivy, Percy, Supko, Jeffrey G, Tabar, Viviane, Omuro, Antonio

Volltext

Phase I study of RO4929097 with bevacizumab in patients with recurrent malignant glioma von Pan, Edward, Supko, Jeffrey G., Kaley, Thomas J., Butowski, Nicholas A., Cloughesy, Timothy, Jung, Jinkyu, Desideri, Serena, Grossman, Stuart, Ye, Xiaobu, Park, Deric M.

Volltext

Multicenter Phase IB Trial of Carboxyamidotriazole Orotate and Temozolomide for Recurrent and Newly Diagnosed Glioblastoma and Other Anaplastic Gliomas von Omuro, Antonio, Beal, Kathryn, McNeill, Katharine, Young, Robert J, Thomas, Alissa, Lin, Xuling, Terziev, Robert, Kaley, Thomas J, DeAngelis, Lisa M, Daras, Mariza, Gavrilovic, Igor T, Mellinghoff, Ingo, Diamond, Eli L, McKeown, Andrew, Manne, Malbora, Caterfino, Andrew, Patel, Krishna, Bavisotto, Linda, Gorman, Greg, Lamson, Michael, Gutin, Philip, Tabar, Viviane, Chakravarty, Debyani, Chan, Timothy A, Brennan, Cameron W, Garrett-Mayer, Elizabeth, Karmali, Rashida A, Pentsova, Elena

Volltext