Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis von Dixon, Scott J, Patel, Darpan N, Welsch, Matthew, Skouta, Rachid, Lee, Eric D, Hayano, Miki, Thomas, Ajit G, Gleason, Caroline E, Tatonetti, Nicholas P, Slusher, Barbara S, Stockwell, Brent R

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Preventing Allograft Rejection by Targeting Immune Metabolism von Lee, Chen-Fang, Lo, Ying-Chun, Cheng, Chih-Hsien, Furtmüller, Georg J., Oh, Byoungchol, Andrade-Oliveira, Vinicius, Thomas, Ajit G., Bowman, Caitlyn E., Slusher, Barbara S., Wolfgang, Michael J., Brandacher, Gerald, Powell, Jonathan D.

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Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis von Xiang, Yan, Stine, Zachary E, Xia, Jinsong, Lu, Yunqi, O'Connor, Roddy S, Altman, Brian J, Hsieh, Annie L, Gouw, Arvin M, Thomas, Ajit G, Gao, Ping, Sun, Linchong, Song, Libing, Yan, Benedict, Slusher, Barbara S, Zhuo, Jingli, Ooi, London L, Lee, Caroline G L, Mancuso, Anthony, McCallion, Andrew S, Le, Anne, Milone, Michael C, Rayport, Stephen, Felsher, Dean W, Dang, Chi V

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Cambinol, a novel inhibitor of neutral sphingomyelinase 2 shows neuroprotective properties von Figuera-Losada, Mariana, Stathis, Marigo, Dorskind, Joelle M, Thomas, Ajit G, Bandaru, Veera Venkata Ratnam, Yoo, Seung-Wan, Westwood, Nicholas J, Rogers, Graeme W, McArthur, Justin C, Haughey, Norman J, Slusher, Barbara S, Rojas, Camilo

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Maternal inflammation leads to impaired glutamate homeostasis and up-regulation of glutamate carboxypeptidase II in activated microglia in the fetal/newborn rabbit brain von Zhang, Zhi, Bassam, Bassam, Thomas, Ajit G, Williams, Monica, Liu, Jinhuan, Nance, Elizabeth, Rojas, Camilo, Slusher, Barbara S, Kannan, Sujatha

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Netupitant and palonosetron trigger NK1 receptor internalization in NG108-15 cells von Thomas, Ajit G., Stathis, Marigo, Rojas, Camilo, Slusher, Barbara S.

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Neutral sphingomyelinase 2 inhibition attenuates extracellular vesicle release and improves neurobehavioral deficits in murine HIV von Zhu, Xiaolei, Hollinger, Kristen R., Huang, Yiyao, Borjabad, Alejandra, Kim, Boe-Hyun, Arab, Tanina, Thomas, Ajit G., Moniruzzaman, Mohammed, Lovell, Lyndah, Turchinovich, Andrey, Witwer, Kenneth W., Volsky, David J., Haughey, Norman J., Slusher, Barbara S.

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High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells von Thomas, Ajit G, Sattler, Rita, Tendyke, Karen, Loiacono, Kara A, Hansen, Hans, Sahni, Vishal, Hashizume, Yutaka, Rojas, Camilo, Slusher, Barbara S

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Palonosetron triggers 5-HT3 receptor internalization and causes prolonged inhibition of receptor function von ROJAS, Camilo, THOMAS, Ajit G, ALT, Jesse, STATHIS, Marigo, JIE ZHANG, RUBENSTEIN, Edward B, SEBASTIANI, Silvia, CANTOREGGI, Sergio, SLUSHER, Barbara S

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The Antiemetic 5-HT3 Receptor Antagonist Palonosetron Inhibits Substance P-Mediated Responses In Vitro and In Vivo von Rojas, Camilo, Li, Ying, Zhang, Jie, Stathis, Marigo, Alt, Jesse, Thomas, Ajit G., Cantoreggi, Sergio, Sebastiani, Silvia, Pietra, Claudio, Slusher, Barbara S.

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Kinetic characterization of ebselen, chelerythrine and apomorphine as glutaminase inhibitors von Thomas, Ajit G., Rojas, Camilo, Tanega, Cordelle, Shen, Min, Simeonov, Anton, Boxer, Matthew B., Auld, Douglas S., Ferraris, Dana V., Tsukamoto, Takashi, Slusher, Barbara S.

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Synthesis and Biological Evaluation of d-Amino Acid Oxidase Inhibitors von Ferraris, Dana, Duvall, Bridget, Ko, Yao-Sen, Thomas, Ajit G, Rojas, Camilo, Majer, Pavel, Hashimoto, Kenji, Tsukamoto, Takashi

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Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in an Alzheimer's disease mouse model von Tallon, Carolyn, Bell, Benjamin J, Malvankar, Medhinee M, Deme, Pragney, Nogueras-Ortiz, Carlos, Eren, Erden, Thomas, Ajit G, Hollinger, Kristen R, Pal, Arindom, Mustapic, Maja, Huang, Meixiang, Coleman, Kaleem, Joe, Tawnjerae R, Rais, Rana, Haughey, Norman J, Kapogiannis, Dimitrios, Slusher, Barbara S

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T cell metabolic reprogramming in acute kidney injury and protection by glutamine blockade von Lee, Kyungho, Thompson, Elizabeth A, Gharaie, Sepideh, Patel, Chirag H, Kurzhagen, Johanna T, Pierorazio, Phillip M, Arend, Lois J, Thomas, Ajit G, Noel, Sanjeev, Slusher, Barbara S, Rabb, Hamid

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Dendrimer-Conjugated nSMase2 Inhibitor Reduces Tau Propagation in Mice von Tallon, Carolyn, Bell, Benjamin J, Sharma, Anjali, Pal, Arindom, Malvankar, Medhinee M, Thomas, Ajit G, Yoo, Seung-Wan, Hollinger, Kristen R, Coleman, Kaleem, Wilkinson, Elizabeth L, Kannan, Sujatha, Haughey, Norman J, Kannan, Rangaramanujam M, Rais, Rana, Slusher, Barbara S

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Microglial-Targeted nSMase2 Inhibitor Fails to Reduce Tau Propagation in PS19 Mice von Huang, Meixiang, Tallon, Carolyn, Zhu, Xiaolei, Huizar, Kaitlyn D J, Picciolini, Silvia, Thomas, Ajit G, Tenora, Lukas, Liyanage, Wathsala, Rodà, Francesca, Gualerzi, Alice, Kannan, Rangaramanujam M, Bedoni, Marzia, Rais, Rana, Slusher, Barbara S

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D-DOPA Is a Potent, Orally Bioavailable, Allosteric Inhibitor of Glutamate Carboxypeptidase II von Gori, Sadakatali S, Thomas, Ajit G, Pal, Arindom, Wiseman, Robyn, Ferraris, Dana V, Gao, Run-Duo, Wu, Ying, Alt, Jesse, Tsukamoto, Takashi, Slusher, Barbara S, Rais, Rana

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Pharmacokinetics of Intranasal versus Subcutaneous Insulin in the Mouse von Nedelcovych, Michael T, Gadiano, Alexandra J, Wu, Ying, Manning, Arena A, Thomas, Ajit G, Khuder, Saja S, Yoo, Seung-Wan, Xu, Jiadi, McArthur, Justin C, Haughey, Norman J, Volsky, David J, Rais, Rana, Slusher, Barbara S

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Pharmacokinetics of Oral d-Serine in d-Amino Acid Oxidase Knockout Mice von Rais, Rana, Thomas, Ajit G., Wozniak, Krystyna, Wu, Ying, Jaaro-Peled, Hanna, Sawa, Akira, Strick, Christine A., Engle, Sandra J., Brandon, Nicholas J., Rojas, Camilo, Slusher, Barbara S., Tsukamoto, Takashi

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Targeting Mitochondria in Tumor-Associated Macrophages using a Dendrimer-Conjugated TSPO Ligand that Stimulates Antitumor Signaling in Glioblastoma von Sharma, Anjali, Liaw, Kevin, Sharma, Rishi, Thomas, Ajit G, Slusher, Barbara S, Kannan, Sujatha, Kannan, Rangaramanujam M

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