X-ray structures of the high-affinity copper transporter Ctr1 von Ren, Feifei, Logeman, Brandon L., Zhang, Xiaohui, Liu, Yongjian, Thiele, Dennis J., Yuan, Peng

Volltext

New Roles for Copper Metabolism in Cell Proliferation, Signaling, and Disease von Turski, Michelle L., Thiele, Dennis J.

Volltext

Mechanisms for copper acquisition, distribution and regulation von Kim, Byung-Eun, Nevitt, Tracy, Thiele, Dennis J

Volltext

Heat shock transcription factor 1 as a therapeutic target in neurodegenerative diseases von Neef, Daniel W., Jaeger, Alex M., Thiele, Dennis J.

Volltext

Copper Acquisition and Utilization in Fungi von Smith, Aaron D, Logeman, Brandon L, Thiele, Dennis J

Volltext

Host iron withholding demands siderophore utilization for Candida glabrata to survive macrophage killing von Nevitt, Tracy, Thiele, Dennis J

Volltext

A Direct Regulatory Interaction between Chaperonin TRiC and Stress-Responsive Transcription Factor HSF1 von Neef, Daniel W., Jaeger, Alex M., Gomez-Pastor, Rocio, Willmund, Felix, Frydman, Judith, Thiele, Dennis J.

Volltext

A Novel Role for Copper in Ras/Mitogen-Activated Protein Kinase Signaling von Turski, Michelle L., Brady, Donita C., Kim, Hyung J., Kim, Byung-Eun, Nose, Yasuhiro, Counter, Christopher M., Winge, Dennis R., Thiele, Dennis J.

Volltext

Cryptococcus neoformans Copper Detoxification Machinery Is Critical for Fungal Virulence von Ding, Chen, Festa, Richard A., Chen, Ying-Lien, Espart, Anna, Palacios, Òscar, Espín, Jordi, Capdevila, Mercè, Atrian, Sílvia, Heitman, Joseph, Thiele, Dennis J.

Volltext

Copper in Microbial Pathogenesis: Meddling with the Metal von Samanovic, Marie I., Ding, Chen, Thiele, Dennis J., Darwin, K. Heran

Volltext

Modulation of heat shock transcription factor 1 as a therapeutic target for small molecule intervention in neurodegenerative disease von Neef, Daniel W, Turski, Michelle L, Thiele, Dennis J

Volltext

Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington’s disease von Gomez-Pastor, Rocio, Burchfiel, Eileen T., Neef, Daniel W., Jaeger, Alex M., Cabiscol, Elisa, McKinstry, Spencer U., Doss, Argenia, Aballay, Alejandro, Lo, Donald C., Akimov, Sergey S., Ross, Christopher A., Eroglu, Cagla, Thiele, Dennis J.

Volltext

Disulfiram (DSF) acts as a copper ionophore to induce copper-dependent oxidative stress and mediate anti-tumor efficacy in inflammatory breast cancer von Allensworth, Jennifer L., Evans, Myron K., Bertucci, François, Aldrich, Amy J., Festa, Richard A., Finetti, Pascal, Ueno, Naoto T., Safi, Rachid, McDonnell, Donald P., Thiele, Dennis J., Van Laere, Steven, Devi, Gayathri R.

Volltext

Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors von Jaeger, Alex M, Pemble, Charles W, Sistonen, Lea, Thiele, Dennis J

Volltext

Coordinated Remodeling of Cellular Metabolism during Iron Deficiency through Targeted mRNA Degradation von Puig, Sergi, Askeland, Eric, Thiele, Dennis J.

Volltext

Cathepsin Protease Controls Copper and Cisplatin Accumulation via Cleavage of the Ctr1 Metal-binding Ectodomain von Öhrvik, Helena, Logeman, Brandon, Turk, Boris, Reinheckel, Thomas, Thiele, Dennis J.

Volltext

Interactions between copper homeostasis and the fungal cell wall affect copper stress resistance von Probst, Corinna, Garcia-Santamarina, Sarela, Brooks, Jacob T, Van Der Kloet, Inge, Baars, Oliver, Ralle, Martina, Thiele, Dennis J, Alspaugh, J Andrew

Volltext

Copper at the front line of the host-pathogen battle von Festa, Richard A, Thiele, Dennis J

Volltext

Spliceosomal Prp8 intein at the crossroads of protein and RNA splicing von Green, Cathleen M, Li, Zhong, Smith, Aaron D, Novikova, Olga, Bacot-Davis, Valjean R, Gao, Fengshan, Hu, Saiyang, Banavali, Nilesh K, Thiele, Dennis J, Li, Hongmin, Belfort, Marlene

Volltext

Regulation of heat shock transcription factors and their roles in physiology and disease von Gomez-Pastor, Rocio, Burchfiel, Eileen T., Thiele, Dennis J.

Volltext