Exploratory Genome-Wide Interaction Analysis of Nonsteroidal Anti-inflammatory Drugs and Predicted Gene Expression on Colorectal Cancer Risk von Wang, Xiaoliang, Su, Yu-Ru, Petersen, Paneen S., Bien, Stephanie, Schmit, Stephanie L., Drew, David A., Albanes, Demetrius, Berndt, Sonja, Brenner, Hermann, Campbell, Peter T., Casey, Graham, Cheng-Claude, Jenny, Gallinger, Steven, Gruber, Stephen B., Haile, Robert W., Harrison, Tabitha A., Hoffmeister, Michael, Jacobs, Eric J., Jenkins, Mark A., Joshi, Amit D., Li, Li, Lin, Yi, Lindor, Noralane M., Le Marchand, Loic, Martin, Vicente, Milne, Roger, Maclnnis, Robert, Moreno, Victor, Nan, Hongmei, Newcomb, Polly A., Potter, John D., Rennert, Gad, Rennert, Hedy S., Slattery, Martha L., Thibodeau, Stephen N., Weinstein, Stephanie J., Woods, Michael O., Chan, Andrew T., White, Emily, Hsu, Li, Peters, Ulrike

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Exploratory genome-wide interaction analysis of non-steroidal anti-inflammatory drugs and predicted gene expression on colorectal cancer risk von Wang, Xiaoliang, Su, Yu-Ru, Petersen, Paneen S., Bien, Stephanie, Schmit, Stephanie L, Drew, David A., Albanes, Demetrius, Berndt, Sonja I, Brenner, Hermann, Campbell, Peter T, Casey, Graham, Chang-Claude, Jenny, Gallinger, Steven J, Gruber, Stephen B, Haile, Robert W, Harrison, Tabitha A, Hoffmeister, Michael, Jacobs, Eric J, Jenkins, Mark A, Joshi, Amit D., Li, Li, Lin, Yi, Lindor, Noralane M, Marchand, Loïc Le, Martin, Vicente, Milne, Roger, Maclnnis, Robert, Moreno, Victor, Nan, Hongmei, Newcomb, Polly A, Potter, John D, Rennert, Gad, Rennert, Hedy, Slattery, Martha L, Thibodeau, Steve N, Weinstein, Stephanie J, Woods, Michael O, Chan, Andrew T, White, Emily, Hsu, Li, Peters, Ulrike

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Abstract 2965: Functionally informed genome-wide interaction analysis of nonsteroidal anti-inflammatory drugs on colorectal cancer risk von Wang, Xiaoliang, Su, Yu-Ru, Chan, Andrew T., Bien, Stephanie, Bernt, Sonja I., Brenner, Hermann, Casey, Graham, Chang-Claude, Jenny, Gallinger, Steven J., Haile, Robert W., Harrison, Tabitha A., Hoffmeister, Michael, Jenkins, Mark A., Joshi, Amit, Lin, Yi, Lindor, Noralane M., Marchand, Loic Le, Nan, Hongmei, Newcomb, Polly A., Potter, John D., Slattery, Martha L., Thibodeau, Steve N., White, Emily, Hsu, Li, Peters, Ulrike

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Lower Cancer Incidence in Amsterdam-I Criteria Families Without Mismatch Repair Deficiency: Familial Colorectal Cancer Type X von Lindor, Noralane M, Rabe, Kari, Petersen, Gloria M, Haile, Robert, Casey, Graham, Baron, John, Gallinger, Steve, Bapat, Bharati, Aronson, Melyssa, Hopper, John, Jass, Jeremy, LeMarchand, Loic, Grove, John, Potter, John, Newcomb, Polly, Terdiman, Jonathan P, Conrad, Peggy, Moslein, Gabriella, Goldberg, Richard, Ziogas, Argyrios, Anton-Culver, Hoda, de Andrade, Mariza, Siegmund, Kim, Thibodeau, Stephen N, Boardman, Lisa A, Seminara, Daniela

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Cancer Risks for MLH1 and MSH2 Mutation Carriers von Dowty, James G., Win, Aung K., Buchanan, Daniel D., Lindor, Noralane M., Macrae, Finlay A., Clendenning, Mark, Antill, Yoland C., Thibodeau, Stephen N., Casey, Graham, Gallinger, Steve, Marchand, Loic Le, Newcomb, Polly A., Haile, Robert W., Young, Graeme P., James, Paul A., Giles, Graham G., Gunawardena, Shanaka R., Leggett, Barbara A., Gattas, Michael, Boussioutas, Alex, Ahnen, Dennis J., Baron, John A., Parry, Susan, Goldblatt, Jack, Young, Joanne P., Hopper, John L., Jenkins, Mark A.

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Risks of Lynch Syndrome Cancers for MSH6 Mutation Carriers von Baglietto, Laura, Lindor, Noralane M., Dowty, James G., White, Darren M., Wagner, Anja, Gomez Garcia, Encarna B., Vriends, Annette H. J. T., Cartwright, Nicola R., Barnetson, Rebecca A., Farrington, Susan M., Tenesa, Albert, Hampel, Heather, Buchanan, Daniel, Arnold, Sven, Young, Joanne, Walsh, Michael D., Jass, Jeremy, Macrae, Finlay, Antill, Yoland, Winship, Ingrid M., Giles, Graham G., Goldblatt, Jack, Parry, Susan, Suthers, Graeme, Leggett, Barbara, Butz, Malinda, Aronson, Melyssa, Poynter, Jenny N., Baron, John A., Le Marchand, Loic, Haile, Robert, Gallinger, Steve, Hopper, John L., Potter, John, de la Chapelle, Albert, Vasen, Hans F., Dunlop, Malcolm G., Thibodeau, Stephen N., Jenkins, Mark A.

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Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans von Amin Al Olama, Ali, Dadaev, Tokhir, Hazelett, Dennis J, Li, Qiuyan, Leongamornlert, Daniel, Saunders, Edward J, Stephens, Sarah, Cieza-Borrella, Clara, Whitmore, Ian, Benlloch Garcia, Sara, Giles, Graham G, Southey, Melissa C, Fitzgerald, Liesel, Gronberg, Henrik, Wiklund, Fredrik, Aly, Markus, Henderson, Brian E, Schumacher, Fredrick, Haiman, Christopher A, Schleutker, Johanna, Wahlfors, Tiina, Tammela, Teuvo L, Nordestgaard, Børge G, Key, Tim J, Travis, Ruth C, Neal, David E, Donovan, Jenny L, Hamdy, Freddie C, Pharoah, Paul, Pashayan, Nora, Khaw, Kay-Tee, Stanford, Janet L, Thibodeau, Stephen N, Mcdonnell, Shannon K, Schaid, Daniel J, Maier, Christiane, Vogel, Walther, Luedeke, Manuel, Herkommer, Kathleen, Kibel, Adam S, Cybulski, Cezary, Wokołorczyk, Dominika, Kluzniak, Wojciech, Cannon-Albright, Lisa, Brenner, Hermann, Butterbach, Katja, Arndt, Volker, Park, Jong Y, Sellers, Thomas, Lin, Hui-Yi, Slavov, Chavdar, Kaneva, Radka, Mitev, Vanio, Batra, Jyotsna, Clements, Judith A, Spurdle, Amanda, Teixeira, Manuel R, Paulo, Paula, Maia, Sofia, Pandha, Hardev, Michael, Agnieszka, Kierzek, Andrzej, Govindasami, Koveela, Guy, Michelle, Lophatonanon, Artitaya, Muir, Kenneth, Viñuela, Ana, Brown, Andrew A, Freedman, Mathew, Conti, David V, Easton, Douglas, Coetzee, Gerhard A, Eeles, Rosalind A, Kote-Jarai, Zsofia

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Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A von Wang, Hansong, Burnett, Terrilea, Kono, Suminori, Haiman, Christopher A., Iwasaki, Motoki, Wilkens, Lynne R., Loo, Lenora W. M., Van Den Berg, David, Kolonel, Laurence N., Henderson, Brian E., Keku, Temitope O., Sandler, Robert S., Signorello, Lisa B., Blot, William J., Newcomb, Polly A., Pande, Mala, Amos, Christopher I., West, Dee W., Bézieau, Stéphane, Berndt, Sonja I., Zanke, Brent W., Hsu, Li, Lindor, Noralane M., Haile, Robert W., Hopper, John L., Jenkins, Mark A., Gallinger, Steven, Casey, Graham, Stenzel, Stephanie L., Schumacher, Fredrick R., Peters, Ulrike, Gruber, Stephen B., Tsugane, Shoichiro, Stram, Daniel O., Le Marchand, Loïc

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Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study von Morales Berstein, Fernanda, McCartney, Daniel L, Lu, Ake T, Tsilidis, Konstantinos K, Bouras, Emmanouil, Haycock, Philip, Burrows, Kimberley, Phipps, Amanda I, Buchanan, Daniel D, Cheng, Iona, Martin, Richard M, Davey Smith, George, Relton, Caroline L, Horvath, Steve, Marioni, Riccardo E, Richardson, Tom G, Richmond, Rebecca C

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Immunohistochemistry Versus Microsatellite Instability Testing in Phenotyping Colorectal Tumors von Lindor, N. M.

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Mutations in CHEK2 Associated with Prostate Cancer Risk von Dong, Xiangyang, Wang, Liang, Taniguchi, Ken, Wang, Xianshu, Cunningham, Julie M., McDonnell, Shannon K., Qian, Chiping, Marks, Angela F., Slager, Susan L., Peterson, Brett J., Smith, David I., Cheville, John C., Blute, Michael L., Jacobsen, Steve J., Schaid, Daniel J., Tindall, Donald J., Thibodeau, Stephen N., Liu, Wanguo

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The All of Us Research Program: Data quality, utility, and diversity von Ramirez, Andrea H., Halvorson, Alese, Qian, Jun, Mayo, Kelsey, Basford, Melissa, Deflaux, Nicole, Muthuraman, Karthik N., Xu, Hua, Wilkins, Consuelo, Anton-Culver, Hoda, Boerwinkle, Eric, Cohn, Elizabeth, Schully, Sheri D., Argos, Maria, Cronin, Robert M., O’Donnell, Christopher, Fouad, Mona, Greenland, Philip, Hebbring, Scott J., Karlson, Elizabeth W., Khatri, Parinda, Korf, Bruce, Sodeke, Stephen, Wilbanks, John, Hentges, Justin, Mockrin, Stephen, Lunt, Christopher, Devaney, Stephanie A., Gebo, Kelly, Denny, Joshua C., Harris, Paul A., Roden, Dan M., Ahmedani, Brian, Cole Johnson, Christine D., Ahsan, Habib, Antoine-LaVigne, Donna, Anton-Culver, Hoda, Topol, Eric, Jain, Praduman, Korf, Bruce, Behringer, Melissa, Gharavi, Ali G., Hripcsak, George, Bier, Louise, Hebbring, Scott Joseph, Burnside, Elizabeth, Drezner, Marc K., Channamsetty, Veena, Montalvo, Wanda, Chinea, Carmen, Jenks, Nancy, Cicek, Mine, Thibodeau, Steve, Collier, Ever, Winkler, Joyce, Corcoran, John, Daviglus, Martha, Denny, Joshua, Doheny, Kim, Eichler, Evan, Lennon, Niall, Gabriel, Stacey, Gibbs, Richard, Gil Rico, Edgar M., Glazer, David, Greenland, Philip, Hogan, William R., Pollan, Cliff, Okun, Sally, Karlson, Elizabeth W., Smoller, Jordan, Ross, Margaret Elizabeth, Kaushal, Rainu, Khatri, Parinda, Kheterpal, Vik, Ojo, Akinlolu, Moreno, Francisco A., Menon, Usha, Malik-Gagnon, Lynda, Mangravite, Lara, Marallo, Adria, Visweswaran, Shyam, Reis, Steven, Moore, John, Talavera, Gregory, O'Donnell, Christopher, Ohno-Machado, Lucila, Randal, Fornessa, Theodorou, Andreas A., Roxas-Murray, Mercedita, Stark, Louisa, Tepp, Ronnie, Topper, Scott, Weidman, Lisa, Weiss, Scott T., Wellis, David, Whittle, Jeffrey, Wilson, Amanda, Zuchner, Stephan, Zwick, Michael E.

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A PSA SNP associates with cellular function and clinical outcome in men with prostate cancer von Srinivasan, Srilakshmi, Kryza, Thomas, Bock, Nathalie, Tse, Brian W. C., Sokolowski, Kamil A., Janaththani, Panchadsaram, Fernando, Achala, Moya, Leire, Stephens, Carson, Dong, Ying, Röhl, Joan, Alinezhad, Saeid, Vela, Ian, Perry-Keene, Joanna L., Buzacott, Katie, Nica, Robert, Gago-Dominguez, Manuela, Schleutker, Johanna, Maier, Christiane, Muir, Kenneth, Tangen, Catherine M., Gronberg, Henrik, Pashayan, Nora, Albanes, Demetrius, Wolk, Alicja, Stanford, Janet L., Berndt, Sonja I., Mucci, Lorelei A., Koutros, Stella, Cussenot, Olivier, Sorensen, Karina Dalsgaard, Grindedal, Eli Marie, Travis, Ruth C., Haiman, Christopher A., MacInnis, Robert J., Vega, Ana, Wiklund, Fredrik, Neal, David E., Kogevinas, Manolis, Penney, Kathryn L., Nordestgaard, Børge G., Brenner, Hermann, John, Esther M., Gamulin, Marija, Claessens, Frank, Melander, Olle, Dahlin, Anders, Stattin, Pär, Hallmans, Göran, Häggström, Christel, Johansson, Robert, Thysell, Elin, Rönn, Ann-Charlotte, Li, Weiqiang, Brown, Nigel, Dimeski, Goce, Shepherd, Benjamin, Dadaev, Tokhir, Brook, Mark N., Spurdle, Amanda B., Stenman, Ulf-Håkan, Koistinen, Hannu, Kote-Jarai, Zsofia, Klein, Robert J., Lilja, Hans, Ecker, Rupert C., Eeles, Rosalind, Clements, Judith, Batra, Jyotsna

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Conversion Analysis for Mutation Detection in MLH1 and MSH2 in Patients With Colorectal Cancer von Casey, Graham, Lindor, Noralane M, Papadopoulos, Nickolas, Thibodeau, Stephen N, Moskow, John, Steelman, Scott, Buzin, Carolyn H, Sommer, Steve S, Collins, Christine E, Butz, Malinda, Aronson, Melyssa, Gallinger, Steven, Barker, Melissa A, Young, Joanne P, Jass, Jeremy R, Hopper, John L, Diep, Anh, Bapat, Bharati, Salem, Michael, Seminara, Daniela, Haile, Robert, Colon Cancer Family Registry, for the

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Absence of PMS2 mutations in colon-CFR participants whose colorectal cancers demonstrate unexplained loss of MLH1 expression von Clendenning, M, Macrae, FA, Walsh, MD, Walters, RJ, Thibodeau, SN, Gunawardena, SR, Potter, JD, Haile, RW, Gallinger, S, Hopper, JL, Jenkins, MA, Rosty, C, Young, JP, Buchanan, DD

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Prediction of individual genetic risk to prostate cancer using a polygenic score von Szulkin, Robert, Whitington, Thomas, Eklund, Martin, Aly, Markus, Eeles, Rosalind A., Easton, Douglas, Kote-Jarai, ZSofia, Amin Al Olama, Ali, Benlloch, Sara, Muir, Kenneth, Giles, Graham G., Southey, Melissa C., Fitzgerald, Liesel M., Henderson, Brian E., Schumacher, Fredrick, Haiman, Christopher A., Schleutker, Johanna, Wahlfors, Tiina, Tammela, Teuvo LJ, Nordestgaard, Børge G., Key, Tim J., Travis, Ruth C., Neal, David E., Donovan, Jenny L., Hamdy, Freddie C., Pharoah, Paul, Pashayan, Nora, Khaw, Kay-Tee, Stanford, Janet L., Thibodeau, Stephen N., McDonnell, Shannon K., Schaid, Daniel J., Maier, Christiane, Vogel, Walther, Luedeke, Manuel, Herkommer, Kathleen, Kibel, Adam S., Cybulski, Cezary, Lubiński, Jan, Kluźniak, Wojciech, Cannon-Albright, Lisa, Brenner, Hermann, Butterbach, Katja, Stegmaier, Christa, Park, Jong Y., Sellers, Thomas, Lim, Hui-Yi, Slavov, Chavdar, Kaneva, Radka, Mitev, Vanio, Batra, Jyotsna, Clements, Judith A., BioResource, The Australian Prostate Cancer, Spurdle, Amanda, Teixeira, Manuel R., Paulo, Paula, Maia, Sofia, Pandha, Hardev, Michael, Agnieszka, Kierzek, Andrzej, consortium, the PRACTICAL, Gronberg, Henrik, Wiklund, Fredrik

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The Association of Tumor Microsatellite Instability Phenotype with Family History of Colorectal Cancer von BAPAT, Bharati, LINDOR, Noralane M, COTTERCHIO, Michelle, JENKINS, Mark, GROVE, John, CASEY, Graham, THIBODEAU, Stephen N, BISHOP, D. Timothy, HOPPER, John L, AHNEN, Dennis, NEWCOMB, Polly A, LE MARCHAND, Loic, BARON, John, POTTER, John D, SEMINARA, Daniela, SIEGMUND, Kim, LIN LI, YINGYE ZHENG, HAILE, Robert, GALLINGER, Steve, JASS, Jeremy R, YOUNG, Joanne P

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Alpha-1-antitrypsin deficiency and smoking as risk factors for mismatch repair deficient colorectal cancer: A study from the colon cancer family registry von Lindor, Noralane M., Yang, Ping, Evans, Ilonka, Schowalter, Karen, De Andrade, Mariza, Li, Jia, Jeavons, Elysia, Peterson, Gloria, Gallinger, Steve, Bapat, Bharati, Hopper, John, Jass, Jeremy, Jenkins, Mark, Templeton, Allyson, Potter, John, Newcomb, Polly A., LeMarchand, Loic, Grove, John, Haile, Robert, Baron, John, Seminara, Daniela, Limburg, Paul, Thibodeau, Stephen N.

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Pubertal development and prostate cancer risk: Mendelian randomization study in a population-based cohort von Bonilla, Carolina, Lewis, Sarah J, Martin, Richard M, Donovan, Jenny L, Hamdy, Freddie C, Neal, David E, Eeles, Rosalind, Easton, Doug, Kote-Jarai, Zsofia, Al Olama, Ali Amin, Benlloch, Sara, Muir, Kenneth, Giles, Graham G, Wiklund, Fredrik, Gronberg, Henrik, Haiman, Christopher A, Schleutker, Johanna, Nordestgaard, Børge G, Travis, Ruth C, Pashayan, Nora, Khaw, Kay-Tee, Stanford, Janet L, Blot, William J, Thibodeau, Stephen, Maier, Christiane, Kibel, Adam S, Cybulski, Cezary, Cannon-Albright, Lisa, Brenner, Hermann, Park, Jong, Kaneva, Radka, Batra, Jyotsna, Teixeira, Manuel R, Pandha, Hardev, Lathrop, Mark, Davey Smith, George

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Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium von Lophatananon, Artitaya, Stewart-Brown, Sarah, Kote-Jarai, Zsofia, Olama, Ali Amin Al, Garcia, Sara Benlloch, Neal, David E, Hamdy, Freddie C, Donovan, Jenny L, Giles, Graham G, Fitzgerald, Liesel M, Southey, Melissa C, Pharoah, Paul, Pashayan, Nora, Gronberg, Henrik, Wiklund, Fredrik, Aly, Markus, Stanford, Janet L, Brenner, Hermann, Dieffenbach, Aida K, Arndt, Volker, Park, Jong Y, Lin, Hui-Yi, Sellers, Thomas, Slavov, Chavdar, Kaneva, Radka, Mitev, Vanio, Batra, Jyotsna, Spurdle, Amanda, Clements, Judith A, Easton, Douglas, Eeles, Rosalind A, Muir, Kenneth

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