Conformationally Constrained ortho-Anilino Diaryl Ureas: Discovery of 1‑(2-(1′-Neopentylspiro[indoline-3,4′-piperidine]-1-yl)phenyl)-3-(4-(trifluoromethoxy)phenyl)urea, a Potent, S... von Qiao, Jennifer X, Wang, Tammy C, Ruel, Réjean, Thibeault, Carl, L’Heureux, Alexandre, Schumacher, William A, Spronk, Steven A, Hiebert, Sheldon, Bouthillier, Gilles, Lloyd, John, Pi, Zulan, Schnur, Dora M, Abell, Lynn M, Hua, Ji, Price, Laura A, Liu, Eddie, Wu, Qimin, Steinbacher, Thomas E, Bostwick, Jeffrey S, Chang, Ming, Zheng, Joanna, Gao, Qi, Ma, Baoqing, McDonnell, Patricia A, Huang, Christine S, Rehfuss, Robert, Wexler, Ruth R, Lam, Patrick Y. S

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New azole antagonists with high affinity for the P2Y(1) receptor von Ruel, Réjean, L'Heureux, Alexandre, Thibeault, Carl, Daris, Jean-Paul, Martel, Alain, Price, Laura A, Wu, Qimin, Hua, Ji, Wexler, Ruth R, Rehfuss, Robert, Lam, Patrick Y S

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New azole antagonists with high affinity for the P2Y1 receptor von Ruel, Réjean, L’Heureux, Alexandre, Thibeault, Carl, Daris, Jean-Paul, Martel, Alain, Price, Laura A., Wu, Qimin, Hua, Ji, Wexler, Ruth R., Rehfuss, Robert, Lam, Patrick Y.S.

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Aligning Potency and Pharmacokinetic Properties for Pyridine-Based NCINIs von Fader, Lee D, Bailey, Murray, Beaulieu, Eric, Bilodeau, François, Bonneau, Pierre, Bousquet, Yves, Carson, Rebekah J, Chabot, Catherine, Coulombe, René, Duan, Jianmin, Fenwick, Craig, Garneau, Michel, Halmos, Ted, Jakalian, Araz, James, Clint, Kawai, Stephen H, Landry, Serge, LaPlante, Steven R, Mason, Stephen W, Morin, Sebastien, Rioux, Nathalie, Simoneau, Bruno, Surprenant, Simon, Thavonekham, Bounkham, Thibeault, Carl, Trinh, Thao, Tsantrizos, Youla, Tsoung, Jennifer, Yoakim, Christiane, Wernic, Dominik

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Identification of 1-{2-[4-chloro-1′-(2,2-dimethylpropyl)-7-hydroxy-1,2-dihydrospiro[indole-3,4′-piperidine]-1-yl]phenyl}-3-{5-chloro-[1,3]thiazolo[5,4-b]pyridin-2-yl}urea, a potent... von Jeon, Yoon T., Yang, Wu, Qiao, Jennifer X., Li, Ling, Ruel, Rejean, Thibeault, Carl, Hiebert, Sheldon, Wang, Tammy C., Wang, Yufeng, Liu, Yajun, Clark, Charles G., Wong, Henry S., Zhu, Juliang, Wu, Dauh-Rurng, Sun, Dawn, Chen, Bang-Chi, Mathur, Arvind, Chacko, Silvi A., Malley, Mary, Chen, Xue-Qing, Shen, Hong, Huang, Christine S., Schumacher, William A., Bostwick, Jeffrey S., Stewart, Anne B., Price, Laura A., Hua, Ji, Li, Danshi, Levesque, Paul C., Seiffert, Dietmar A., Rehfuss, Robert, Wexler, Ruth R., Lam, Patrick Y.S.

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Identification of 1-{2-[4-chloro-1'-(2,2-dimethylpropyl)-7-hydroxy-1,2-dihydrospiro[indole-3,4'-piperidine]-1-yl]phenyl}-3-{5-chloro-[1,3]thiazolo[5,4-b]pyridin-2-yl}urea, a potent... von Jeon, Yoon T, Yang, Wu, Qiao, Jennifer X, Li, Ling, Ruel, Rejean, Thibeault, Carl, Hiebert, Sheldon, Wang, Tammy C, Wang, Yufeng, Liu, Yajun, Clark, Charles G, Wong, Henry S, Zhu, Juliang, Wu, Dauh-Rurng, Sun, Dawn, Chen, Bang-Chi, Mathur, Arvind, Chacko, Silvi A, Malley, Mary, Chen, Xue-Qing, Shen, Hong, Huang, Christine S, Schumacher, William A, Bostwick, Jeffrey S, Stewart, Anne B, Price, Laura A, Hua, Ji, Li, Danshi, Levesque, Paul C, Seiffert, Dietmar A, Rehfuss, Robert, Wexler, Ruth R, Lam, Patrick Y S

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Potent P2Y1 urea antagonists bearing various cyclic amine scaffolds von Ruel, Réjean, L’Heureux, Alexandre, Thibeault, Carl, Lapointe, Philippe, Martel, Alain, Qiao, Jennifer X., Hua, Ji, Price, Laura A., Wu, Qimin, Chang, Ming, Zheng, Joanna, Huang, Christine S., Wexler, Ruth R., Rehfuss, Robert, Lam, Patrick Y.S.

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Conformationally Constrained ortho- Anilino Diaryl Ureas: Discovery of 1-(2-(1′-Neopentylspiro[indoline-3,4′-piperidine]-1-yl)phenyl)-3-(4-(trifluoromethoxy)phenyl)urea, a Potent,... von Qiao, Jennifer X., Wang, Tammy C., Ruel, Réjean, Thibeault, Carl, L’Heureux, Alexandre, Schumacher, William A., Spronk, Steven A., Hiebert, Sheldon, Bouthillier, Gilles, Lloyd, John, Pi, Zulan, Schnur, Dora M., Abell, Lynn M., Hua, Ji, Price, Laura A., Liu, Eddie, Wu, Qimin, Steinbacher, Thomas E., Bostwick, Jeffrey S., Chang, Ming, Zheng, Joanna, Gao, Qi, Ma, Baoqing, McDonnell, Patricia A., Huang, Christine S., Rehfuss, Robert, Wexler, Ruth R., Lam, Patrick Y. S.

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Discovery of Potent, Orally Bioavailable Inhibitors of Human Cytomegalovirus von Fader, Lee, Brault, Martine, Desjardins, Jessica, Dansereau, Nathalie, Lamorte, Louie, Tremblay, Sonia, Bilodeau, François, Bordeleau, Josée, Duplessis, Martin, Gorys, Vida, Gillard, James, Gleason, James L, James, Clint, Joly, Marc-André, Kuhn, Cyrille, Llinas-Brunet, Montse, Luo, Laibin, Morency, Louis, Morin, Sébastien, Parisien, Mathieu, Poirier, Maude, Thibeault, Carl, Trinh, Thao, Sturino, Claudio, Srivastava, Sanjay, Yoakim, Christiane, Franti, Michael

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Discovery and preclinical studies of 5-isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)- N-(2-methyl-1 H-pyrrolo[2,3- b]pyridin-5-yl)pyrrolo[2,1- f][1,2,4]triazin-4-amine (BMS-645737),... von Ruel, Réjean, Thibeault, Carl, L’Heureux, Alexandre, Martel, Alain, Cai, Zhen-Wei, Wei, Donna, Qian, Ligang, Barrish, Joel C., Mathur, Arvind, D’Arienzo, Celia, Hunt, John T., Kamath, Amrita, Marathe, Punit, Zhang, Yueping, Derbin, George, Wautlet, Barri, Mortillo, Steven, Jeyaseelan, Robert, Henley, Benjamin, Tejwani, Ravindra, Bhide, Rajeev S., Trainor, George L., Fargnoli, Joseph, Lombardo, Louis J.

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AMINO-HETEROARYL 7-HYDROXY-SPIROPIPERIDINE INDOLINYL ANTAGONISTS OF P2Y1 RECEPTOR von QIAO, JENNIFER X, THIBEAULT, CARL, HU, CAROL HUI

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NAPHTHYRIDINONE DERIVATIVES AS INHIBITORS OF CYTOMEGALOVIRUS DNA POLYMERASE von PARISIEN, MATHIEU, NAUD, JULIE, BEAULIEU, PIERRE LOUIS, SURPRENANT, SIMON, THIBEAULT, CARL, LEPAGE, OLIVIER, POIRIER, MARTIN, FADER, LEE, MOREAU, BENOIT, GIROUX, ANDRE, BILODEAU, FRANCOIS, CARSON, REBEKAH, BAILEY, MURRAY, POIRIER, MAUDE, GODBOUT, CEDRICKX

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INHIBITORS OF CYTOMEGALOVIRUS von THIBEAULT, Carl, KUHN, Cyrille, BILODEAU, François, PARISIEN, Mathieu, TRINH, Thao, FADER, Lee, POIRIER, Maude

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INHIBITORS OF CYTOMEGALOVIRUS von THIBEAULT, Carl, JAMES, Clint, DUPLESSIS, Martin, PARISIEN, Mathieu, MORENCY, Louis, FADER, Lee, MORIN, Sebastien, GILLARD, James

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Amino-heteroaryl 7-hydroxy-spiropiperidine indolinyl antagonists of P2Y1 receptor von THIBEAULT CARL, QIAO JENNIFER X, HU CAROL HUI

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AMINO-HETEROARYL 7-HYDROXY-SPIROPIPERIDINE INDOLINYL ANTAGONISTS OF P2Y1 RECEPTOR von THIBEAULT CARL, QIAO JENNIFER X, HU CAROL HUI

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AMINO-HETEROARYL 7-HYDROXY-SPIROPIPERIDINE INDOLINYL ANTAGONISTS OF P2Y1 RECEPTOR von QIAO, JENNIFER X, THIBEAULT, CARL, HU, CAROL HUI

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Inhibitors of cytomegalovirus von JAMES CLINT, FADER LEE, MORENCY LOUIS, GILLARD JAMES, PARISIEN MATHIEU, THIBEAULT CARL, MORIN SÉBASTIEN, DUPLESSIS MARTIN

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Inhibitors of human immunodeficiency virus replication von TSANTRIZOS YOULA S, THIBEAULT CARL, YOAKIM CHRISTIANEOF

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Inhibitors of human immunodeficiency virus replication von TSANTRIZOS YOULA S, THIBEAULT CARL, YOAKIM CHRISTIANEOF

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