Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs von Pontis, Julien, Planet, Evarist, Offner, Sandra, Turelli, Priscilla, Duc, Julien, Coudray, Alexandre, Theunissen, Thorold W., Jaenisch, Rudolf, Trono, Didier

Volltext

Molecular Criteria for Defining the Naive Human Pluripotent State von Theunissen, Thorold W., Friedli, Marc, He, Yupeng, Planet, Evarist, O’Neil, Ryan C., Markoulaki, Styliani, Pontis, Julien, Wang, Haoyi, Iouranova, Alexandra, Imbeault, Michaël, Duc, Julien, Cohen, Malkiel A., Wert, Katherine J., Castanon, Rosa, Zhang, Zhuzhu, Huang, Yanmei, Nery, Joseph R., Drotar, Jesse, Lungjangwa, Tenzin, Trono, Didier, Ecker, Joseph R., Jaenisch, Rudolf

Volltext

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency von Theunissen, Thorold W., Powell, Benjamin E., Wang, Haoyi, Mitalipova, Maya, Faddah, Dina A., Reddy, Jessica, Fan, Zi Peng, Maetzel, Dorothea, Ganz, Kibibi, Shi, Linyu, Lungjangwa, Tenzin, Imsoonthornruksa, Sumeth, Stelzer, Yonatan, Rangarajan, Sudharshan, D’Alessio, Ana, Zhang, Jianming, Gao, Qing, Dawlaty, Meelad M., Young, Richard A., Gray, Nathanael S., Jaenisch, Rudolf

Volltext

Molecular Control of Induced Pluripotency von Theunissen, Thorold W., Jaenisch, Rudolf

Volltext

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system von Cheng, Albert W, Wang, Haoyi, Yang, Hui, Shi, Linyu, Katz, Yarden, Theunissen, Thorold W, Rangarajan, Sudharshan, Shivalila, Chikdu S, Dadon, Daniel B, Jaenisch, Rudolf

Volltext

Timing of anterior cruciate ligament reconstruction and preoperative pain are important predictors for postoperative kinesiophobia von Theunissen, W. W. E. S., van der Steen, M. C., Liu, W. Y., Janssen, R. P. A.

Volltext

Promotion of reprogramming to ground state pluripotency by signal inhibition von Silva, Jose, Barrandon, Ornella, Nichols, Jennifer, Kawaguchi, Jitsutaro, Theunissen, Thorold W, Smith, Austin

Volltext

Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation von Sahakyan, Anna, Kim, Rachel, Chronis, Constantinos, Sabri, Shan, Bonora, Giancarlo, Theunissen, Thorold W., Kuoy, Edward, Langerman, Justin, Clark, Amander T., Jaenisch, Rudolf, Plath, Kathrin

Volltext

Derivation of trophoblast stem cells from naïve human pluripotent stem cells von Dong, Chen, Beltcheva, Mariana, Gontarz, Paul, Zhang, Bo, Popli, Pooja, Fischer, Laura A, Khan, Shafqat A, Park, Kyoung-Mi, Yoon, Eun-Ja, Xing, Xiaoyun, Kommagani, Ramakrishna, Wang, Ting, Solnica-Krezel, Lilianna, Theunissen, Thorold W

Volltext

Nanog Is the Gateway to the Pluripotent Ground State von Silva, Jose, Nichols, Jennifer, Theunissen, Thorold W., Guo, Ge, van Oosten, Anouk L., Barrandon, Ornella, Wray, Jason, Yamanaka, Shinya, Chambers, Ian, Smith, Austin

Volltext

Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency von Tee, Wee-Wei, Pardo, Mercedes, Theunissen, Thorold W, Yu, Lu, Choudhary, Jyoti S, Hajkova, Petra, Surani, M Azim

Volltext

A genome-wide CRISPR-Cas9 knockout screen identifies essential and growth-restricting genes in human trophoblast stem cells von Dong, Chen, Fu, Shuhua, Karvas, Rowan M., Chew, Brian, Fischer, Laura A., Xing, Xiaoyun, Harrison, Jessica K., Popli, Pooja, Kommagani, Ramakrishna, Wang, Ting, Zhang, Bo, Theunissen, Thorold W.

Volltext

A protein interaction network for pluripotency of embryonic stem cells von Wang, Jianlong, Rao, Sridhar, Chu, Jianlin, Shen, Xiaohua, Levasseur, Dana N., Theunissen, Thorold W., Orkin, Stuart H.

Volltext

Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency von Yang, Jian, van Oosten, Anouk L., Theunissen, Thorold W., Guo, Ge, Silva, Jose C.R., Smith, Austin

Volltext

Self-renewing human naïve pluripotent stem cells dedifferentiate in 3D culture and form blastoids spontaneously von Guo, Mingyue, Wu, Jinyi, Chen, Chuanxin, Wang, Xinggu, Gong, An, Guan, Wei, Karvas, Rowan M., Wang, Kexin, Min, Mingwei, Wang, Yixuan, Theunissen, Thorold W., Gao, Shaorong, Silva, José C. R.

Volltext

Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening von Khan, Shafqat A, Park, Kyoung-Mi, Fischer, Laura A, Dong, Chen, Lungjangwa, Tenzin, Jimenez, Marta, Casalena, Dominick, Chew, Brian, Dietmann, Sabine, Auld, Douglas S, Jaenisch, Rudolf, Theunissen, Thorold W

Volltext

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency von Theunissen, Thorold W., Powell, Benjamin E., Wang, Haoyi, Mitalipova, Maya, Faddah, Dina A., Reddy, Jessica, Fan, Zi Peng, Maetzel, Dorothea, Ganz, Kibibi, Shi, Linyu, Lungjangwa, Tenzin, Imsoonthornruksa, Sumeth, Stelzer, Yonatan, Rangarajan, Sudharshan, D’Alessio, Ana, Zhang, Jianming, Gao, Qing, Dawlaty, Meelad M., Young, Richard A., Gray, Nathanael S., Jaenisch, Rudolf

Volltext

OCT4 cooperates with distinct ATP-dependent chromatin remodelers in naïve and primed pluripotent states in human von Huang, Xin, Park, Kyoung-mi, Gontarz, Paul, Zhang, Bo, Pan, Joshua, McKenzie, Zachary, Fischer, Laura A., Dong, Chen, Dietmann, Sabine, Xing, Xiaoyun, Shliaha, Pavel V., Yang, Jihong, Li, Dan, Ding, Junjun, Lungjangwa, Tenzin, Mitalipova, Maya, Khan, Shafqat A., Imsoonthornruksa, Sumeth, Jensen, Nick, Wang, Ting, Kadoch, Cigall, Jaenisch, Rudolf, Wang, Jianlong, Theunissen, Thorold W.

Volltext

Mechanisms of gene regulation in human embryos and pluripotent stem cells von Theunissen, Thorold W, Jaenisch, Rudolf

Volltext

Parental experiences of children with developmental dysplasia of the hip: a qualitative study von Theunissen, WWES, van der Steen, MC, van Veen, MR, van Douveren, FQMP, Witlox, MA, Tolk, JJ

Volltext