Molecular Control of Induced Pluripotency von Theunissen, Thorold W., Jaenisch, Rudolf

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Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs von Pontis, Julien, Planet, Evarist, Offner, Sandra, Turelli, Priscilla, Duc, Julien, Coudray, Alexandre, Theunissen, Thorold W., Jaenisch, Rudolf, Trono, Didier

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Molecular Criteria for Defining the Naive Human Pluripotent State von Theunissen, Thorold W., Friedli, Marc, He, Yupeng, Planet, Evarist, O’Neil, Ryan C., Markoulaki, Styliani, Pontis, Julien, Wang, Haoyi, Iouranova, Alexandra, Imbeault, Michaël, Duc, Julien, Cohen, Malkiel A., Wert, Katherine J., Castanon, Rosa, Zhang, Zhuzhu, Huang, Yanmei, Nery, Joseph R., Drotar, Jesse, Lungjangwa, Tenzin, Trono, Didier, Ecker, Joseph R., Jaenisch, Rudolf

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Promotion of reprogramming to ground state pluripotency by signal inhibition von Silva, Jose, Barrandon, Ornella, Nichols, Jennifer, Kawaguchi, Jitsutaro, Theunissen, Thorold W, Smith, Austin

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Mechanisms of gene regulation in human embryos and pluripotent stem cells von Theunissen, Thorold W, Jaenisch, Rudolf

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Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency von Theunissen, Thorold W., Powell, Benjamin E., Wang, Haoyi, Mitalipova, Maya, Faddah, Dina A., Reddy, Jessica, Fan, Zi Peng, Maetzel, Dorothea, Ganz, Kibibi, Shi, Linyu, Lungjangwa, Tenzin, Imsoonthornruksa, Sumeth, Stelzer, Yonatan, Rangarajan, Sudharshan, D’Alessio, Ana, Zhang, Jianming, Gao, Qing, Dawlaty, Meelad M., Young, Richard A., Gray, Nathanael S., Jaenisch, Rudolf

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Accessing the human trophoblast stem cell state from pluripotent and somatic cells von Karvas, Rowan M., David, Laurent, Theunissen, Thorold W.

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Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system von Cheng, Albert W, Wang, Haoyi, Yang, Hui, Shi, Linyu, Katz, Yarden, Theunissen, Thorold W, Rangarajan, Sudharshan, Shivalila, Chikdu S, Dadon, Daniel B, Jaenisch, Rudolf

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Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation von Sahakyan, Anna, Kim, Rachel, Chronis, Constantinos, Sabri, Shan, Bonora, Giancarlo, Theunissen, Thorold W., Kuoy, Edward, Langerman, Justin, Clark, Amander T., Jaenisch, Rudolf, Plath, Kathrin

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Derivation of trophoblast stem cells from naïve human pluripotent stem cells von Dong, Chen, Beltcheva, Mariana, Gontarz, Paul, Zhang, Bo, Popli, Pooja, Fischer, Laura A, Khan, Shafqat A, Park, Kyoung-Mi, Yoon, Eun-Ja, Xing, Xiaoyun, Kommagani, Ramakrishna, Wang, Ting, Solnica-Krezel, Lilianna, Theunissen, Thorold W

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Modeling X-chromosome inactivation and reactivation during human development von Khan, Shafqat A, Theunissen, Thorold W

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Nanog Is the Gateway to the Pluripotent Ground State von Silva, Jose, Nichols, Jennifer, Theunissen, Thorold W., Guo, Ge, van Oosten, Anouk L., Barrandon, Ornella, Wray, Jason, Yamanaka, Shinya, Chambers, Ian, Smith, Austin

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Recent insights into the naïve state of human pluripotency and its applications von Dong, Chen, Fischer, Laura A., Theunissen, Thorold W.

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Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogens von Karvas, Rowan M., Khan, Shafqat A., Verma, Sonam, Yin, Yan, Kulkarni, Devesha, Dong, Chen, Park, Kyoung-mi, Chew, Brian, Sane, Eshan, Fischer, Laura A., Kumar, Deepak, Ma, Liang, Boon, Adrianus C.M., Dietmann, Sabine, Mysorekar, Indira U., Theunissen, Thorold W.

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Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency von Tee, Wee-Wei, Pardo, Mercedes, Theunissen, Thorold W, Yu, Lu, Choudhary, Jyoti S, Hajkova, Petra, Surani, M Azim

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A genome-wide CRISPR-Cas9 knockout screen identifies essential and growth-restricting genes in human trophoblast stem cells von Dong, Chen, Fu, Shuhua, Karvas, Rowan M., Chew, Brian, Fischer, Laura A., Xing, Xiaoyun, Harrison, Jessica K., Popli, Pooja, Kommagani, Ramakrishna, Wang, Ting, Zhang, Bo, Theunissen, Thorold W.

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A protein interaction network for pluripotency of embryonic stem cells von Levasseur, Dana N, Rao, Sridhar, Shen, Xiaohua, Orkin, Stuart H, Wang, Jianlong, Chu, Jianlin, Theunissen, Thorold W

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NANOG-dependent function of TET1 and TET2 in establishment of pluripotency von Costa, Yael, Ding, Junjun, Theunissen, Thorold W., Faiola, Francesco, Hore, Timothy A., Shliaha, Pavel V., Fidalgo, Miguel, Saunders, Arven, Lawrence, Moyra, Dietmann, Sabine, Das, Satyabrata, Levasseur, Dana N., Li, Zhe, Xu, Mingjiang, Reik, Wolf, Silva, José C. R., Wang, Jianlong

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3D-cultured blastoids model human embryogenesis from pre-implantation to early gastrulation stages von Karvas, Rowan M., Zemke, Joseph E., Ali, Syed Shahzaib, Upton, Eric, Sane, Eshan, Fischer, Laura A., Dong, Chen, Park, Kyoung-mi, Wang, Fei, Park, Kibeom, Hao, Senyue, Chew, Brian, Meyer, Brittany, Zhou, Chao, Dietmann, Sabine, Theunissen, Thorold W.

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Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency von Yang, Jian, van Oosten, Anouk L., Theunissen, Thorold W., Guo, Ge, Silva, Jose C.R., Smith, Austin

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