Genetics: Implications for Prevention and Management of Coronary Artery Disease von Assimes, Themistocles L., MD, PhD, Roberts, Robert, MD

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Alcohol use and cardiometabolic risk in the UK Biobank: A Mendelian randomization study von Lankester, Joanna, Zanetti, Daniela, Ingelsson, Erik, Assimes, Themistocles L

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DNA methylation GrimAge strongly predicts lifespan and healthspan von Lu, Ake T, Quach, Austin, Wilson, James G, Reiner, Alex P, Aviv, Abraham, Raj, Kenneth, Hou, Lifang, Baccarelli, Andrea A, Li, Yun, Stewart, James D, Whitsel, Eric A, Assimes, Themistocles L, Ferrucci, Luigi, Horvath, Steve

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Genetics of 35 blood and urine biomarkers in the UK Biobank von Sinnott-Armstrong, Nasa, Tanigawa, Yosuke, Amar, David, Mars, Nina, Benner, Christian, Aguirre, Matthew, Venkataraman, Guhan Ram, Wainberg, Michael, Ollila, Hanna M., Kiiskinen, Tuomo, Havulinna, Aki S., Pirruccello, James P., Qian, Junyang, Shcherbina, Anna, Rodriguez, Fatima, Assimes, Themistocles L., Agarwala, Vineeta, Tibshirani, Robert, Hastie, Trevor, Ripatti, Samuli, Pritchard, Jonathan K., Daly, Mark J., Rivas, Manuel A.

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An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease von Horvath, Steve, Gurven, Michael, Levine, Morgan E, Trumble, Benjamin C, Kaplan, Hillard, Allayee, Hooman, Ritz, Beate R, Chen, Brian, Lu, Ake T, Rickabaugh, Tammy M, Jamieson, Beth D, Sun, Dianjianyi, Li, Shengxu, Chen, Wei, Quintana-Murci, Lluis, Fagny, Maud, Kobor, Michael S, Tsao, Philip S, Reiner, Alexander P, Edlefsen, Kerstin L, Absher, Devin, Assimes, Themistocles L

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The relationship between circulating lipids and breast cancer risk: A Mendelian randomization study von Johnson, Kelsey E, Siewert, Katherine M, Klarin, Derek, Damrauer, Scott M, Chang, Kyong-Mi, Tsao, Philip S, Assimes, Themistocles L, Maxwell, Kara N, Voight, Benjamin F

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The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease von Shirai, Tsuyoshi, Nazarewicz, Rafal R, Wallis, Barbara B, Yanes, Rolando E, Watanabe, Ryu, Hilhorst, Marc, Tian, Lu, Harrison, David G, Giacomini, John C, Assimes, Themistocles L, Goronzy, Jörg J, Weyand, Cornelia M

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Menopause accelerates biological aging von Levine, Morgan E., Lu, Ake T., Chen, Brian H., Hernandez, Dena G., Singleton, Andrew B., Ferrucci, Luigi, Bandinelli, Stefania, Salfati, Elias, Manson, JoAnn E., Quach, Austin, Kusters, Cynthia D. J., Kuh, Diana, Wong, Andrew, Teschendorff, Andrew E., Widschwendter, Martin, Ritz, Beate R., Absher, Devin, Assimes, Themistocles L., Horvath, Steve

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Mendelian randomization analyses clarify the effects of height on cardiovascular diseases von Hui, Daniel, Sanford, Eric, Lorenz, Kimberly, Damrauer, Scott M, Assimes, Themistocles L, Thom, Christopher S, Voight, Benjamin F

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Epigenetic clock analysis of diet, exercise, education, and lifestyle factors von Quach, Austin, Levine, Morgan E, Tanaka, Toshiko, Lu, Ake T, Chen, Brian H, Ferrucci, Luigi, Ritz, Beate, Bandinelli, Stefania, Neuhouser, Marian L, Beasley, Jeannette M, Snetselaar, Linda, Wallace, Robert B, Tsao, Philip S, Absher, Devin, Assimes, Themistocles L, Stewart, James D, Li, Yun, Hou, Lifang, Baccarelli, Andrea A, Whitsel, Eric A, Horvath, Steve

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Leveraging Multi-ethnic Evidence for Risk Assessment of Quantitative Traits in Minority Populations von Coram, Marc A., Fang, Huaying, Candille, Sophie I., Assimes, Themistocles L., Tang, Hua

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Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction von Saw, Jacqueline, Yang, Min-Lee, Trinder, Mark, Tcheandjieu, Catherine, Xu, Chang, Starovoytov, Andrew, Birt, Isabelle, Mathis, Michael R., Hunker, Kristina L., Schmidt, Ellen M., Jackson, Linda, Fendrikova-Mahlay, Natalia, Zawistowski, Matthew, Brummett, Chad M., Zoellner, Sebastian, Katz, Alexander, Coleman, Dawn M., Swan, Kirby, O’Donnell, Christopher J., Zhou, Xiang, Li, Jun Z., Gornik, Heather L., Assimes, Themistocles L., Stanley, James C., Brunham, Liam R., Ganesh, Santhi K.

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Clinical Interpretation and Implications of Whole-Genome Sequencing von Dewey, Frederick E, Grove, Megan E, Pan, Cuiping, Goldstein, Benjamin A, Bernstein, Jonathan A, Chaib, Hassan, Merker, Jason D, Goldfeder, Rachel L, Enns, Gregory M, David, Sean P, Pakdaman, Neda, Ormond, Kelly E, Caleshu, Colleen, Kingham, Kerry, Klein, Teri E, Whirl-Carrillo, Michelle, Sakamoto, Kenneth, Wheeler, Matthew T, Butte, Atul J, Ford, James M, Boxer, Linda, Ioannidis, John P. A, Yeung, Alan C, Altman, Russ B, Assimes, Themistocles L, Snyder, Michael, Ashley, Euan A, Quertermous, Thomas

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Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation von Miller, Clint L, Haas, Ulrike, Diaz, Roxanne, Leeper, Nicholas J, Kundu, Ramendra K, Patlolla, Bhagat, Assimes, Themistocles L, Kaiser, Frank J, Perisic, Ljubica, Hedin, Ulf, Maegdefessel, Lars, Schunkert, Heribert, Erdmann, Jeanette, Quertermous, Thomas, Sczakiel, Georg

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Association Between Heart Failure and Postoperative Mortality Among Patients Undergoing Ambulatory Noncardiac Surgery von Lerman, Benjamin J, Popat, Rita A, Assimes, Themistocles L, Heidenreich, Paul A, Wren, Sherry M

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Long-term use of angiotensin receptor blockers and the risk of cancer von Azoulay, Laurent, Assimes, Themistocles L, Yin, Hui, Bartels, Dorothee B, Schiffrin, Ernesto L, Suissa, Samy

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Methylome-wide association study provides evidence of particulate matter air pollution-associated DNA methylation von Gondalia, Rahul, Baldassari, Antoine, Holliday, Katelyn M., Justice, Anne E., Méndez-Giráldez, Raúl, Stewart, James D., Liao, Duanping, Yanosky, Jeff D., Brennan, Kasey J.M., Engel, Stephanie M., Jordahl, Kristina M., Kennedy, Elizabeth, Ward-Caviness, Cavin K., Wolf, Kathrin, Waldenberger, Melanie, Cyrys, Josef, Peters, Annette, Bhatti, Parveen, Horvath, Steve, Assimes, Themistocles L., Pankow, James S., Demerath, Ellen W., Guan, Weihua, Fornage, Myriam, Bressler, Jan, North, Kari E., Conneely, Karen N., Li, Yun, Hou, Lifang, Baccarelli, Andrea A., Whitsel, Eric A.

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Genome-Wide Association Studies of Coronary Artery Disease: Recent Progress and Challenges Ahead von Clarke, Shoa L., Assimes, Themistocles L.

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Age-Related Somatic Structural Changes in the Nuclear Genome of Human Blood Cells von Forsberg, Lars A., Rasi, Chiara, Razzaghian, Hamid R., Pakalapati, Geeta, Waite, Lindsay, Thilbeault, Krista Stanton, Ronowicz, Anna, Wineinger, Nathan E., Tiwari, Hemant K., Boomsma, Dorret, Westerman, Maxwell P., Harris, Jennifer R., Lyle, Robert, Essand, Magnus, Eriksson, Fredrik, Assimes, Themistocles L., Iribarren, Carlos, Strachan, Eric, O'Hanlon, Terrance P., Rider, Lisa G., Miller, Frederick W., Giedraitis, Vilmantas, Lannfelt, Lars, Ingelsson, Martin, Piotrowski, Arkadiusz, Pedersen, Nancy L., Absher, Devin, Dumanski, Jan P.

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Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci von Miller, Clint L., Pjanic, Milos, Wang, Ting, Nguyen, Trieu, Cohain, Ariella, Lee, Jonathan D., Perisic, Ljubica, Hedin, Ulf, Kundu, Ramendra K., Majmudar, Deshna, Kim, Juyong B., Wang, Oliver, Betsholtz, Christer, Ruusalepp, Arno, Franzén, Oscar, Assimes, Themistocles L., Montgomery, Stephen B., Schadt, Eric E., Björkegren, Johan L.M., Quertermous, Thomas

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