Marked synergy by vertical inhibition of EGFR signaling in NSCLC spheroids shows SOS1 is a therapeutic target in EGFR-mutated cancer von Theard, Patricia L, Sheffels, Erin, Sealover, Nancy E, Linke, Amanda J, Pratico, David J, Kortum, Robert L

Volltext

SOS2 modulates the threshold of EGFR signaling to regulate osimertinib efficacy and resistance in lung adenocarcinoma von Theard, Patricia L., Linke, Amanda J., Sealover, Nancy E., Daley, Brianna R., Yang, Johnny, Cox, Katherine, Kortum, Robert L.

Volltext

Protocol for modeling acquired resistance to targeted therapeutics in adherent and suspension cancer cell lines via in situ resistance assay von Sealover, Nancy E., Hughes, Jacob M., Theard, Patricia L., Chatterjee, Deepan, Linke, Amanda J., Finniff, Bridget A., Daley, Brianna R., Lewis, Robert E., Kortum, Robert L.

Volltext

Anchorage-independent growth conditions reveal a differential SOS2 dependence for transformation and survival in RAS-mutant cancer cells von Sheffels, Erin, Sealover, Nancy E., Theard, Patricia L., Kortum, Robert L.

Volltext

In situ modeling of acquired resistance to RTK/RAS-pathway-targeted therapies von Sealover, Nancy E., Theard, Patricia L., Hughes, Jacob M., Linke, Amanda J., Daley, Brianna R., Kortum, Robert L.

Volltext

High density lipoproteins and type 2 inflammatory biomarkers are negatively correlated in atopic asthmatics von Barochia, Amisha V., Gordon, Elizabeth M., Kaler, Maryann, Cuento, Rosemarie A., Theard, Patricia, Figueroa, Debbie M., Yao, Xianglan, Weir, Nargues A., Sampson, Maureen L., Stylianou, Mario, Choy, David F., Holweg, Cecile T.J., Remaley, Alan T., Levine, Stewart J.

Volltext