A proof-of-concept study for the design of a VLP-based combinatorial HPV and placental malaria vaccine von Janitzek, Christoph M., Peabody, Julianne, Thrane, Susan, H. R. Carlsen, Philip, G. Theander, Thor, Salanti, Ali, Chackerian, Bryce, A. Nielsen, Morten, Sander, Adam F.

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Placental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on Syndecan-1 von Ayres Pereira, Marina, Mandel Clausen, Thomas, Pehrson, Caroline, Mao, Yang, Resende, Mafalda, Daugaard, Mads, Riis Kristensen, Anders, Spliid, Charlotte, Mathiesen, Line, E Knudsen, Lisbeth, Damm, Peter, G Theander, Thor, R Hansson, Stefan, A Nielsen, Morten, Salanti, Ali

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Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity von Fougeroux, Cyrielle, Goksøyr, Louise, Idorn, Manja, Soroka, Vladislav, Myeni, Sebenzile K., Dagil, Robert, Janitzek, Christoph M., Søgaard, Max, Aves, Kara-Lee, Horsted, Emma W., Erdoğan, Sayit Mahmut, Gustavsson, Tobias, Dorosz, Jerzy, Clemmensen, Stine, Fredsgaard, Laurits, Thrane, Susan, Vidal-Calvo, Elena E., Khalifé, Paul, Hulen, Thomas M., Choudhary, Swati, Theisen, Michael, Singh, Susheel K., Garcia-Senosiain, Asier, Van Oosten, Linda, Pijlman, Gorben, Hierzberger, Bettina, Domeyer, Tanja, Nalewajek, Blanka W., Strøbæk, Anette, Skrzypczak, Magdalena, Andersson, Laura F., Buus, Søren, Buus, Anette Stryhn, Christensen, Jan Pravsgaard, Dalebout, Tim J., Iversen, Kasper, Harritshøj, Lene H., Mordmüller, Benjamin, Ullum, Henrik, Reinert, Line S., de Jongh, Willem Adriaan, Kikkert, Marjolein, Paludan, Søren R., Theander, Thor G., Nielsen, Morten A., Salanti, Ali, Sander, Adam F.

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Structural Conservation Despite Huge Sequence Diversity Allows EPCR Binding by the PfEMP1 Family Implicated in Severe Childhood Malaria von Lau, Clinton K.Y., Turner, Louise, Jespersen, Jakob S., Lowe, Edward D., Petersen, Bent, Wang, Christian W., Petersen, Jens E.V., Lusingu, John, Theander, Thor G., Lavstsen, Thomas, Higgins, Matthew K.

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First-in-human, Randomized, Double-blind Clinical Trial of Differentially Adjuvanted PAMVAC, A Vaccine Candidate to Prevent Pregnancy-associated Malaria von Mordmüller, Benjamin, Sulyok, Mihály, Egger-Adam, Diane, Resende, Mafalda, de Jongh, Willem A, Jensen, Mette H, Smedegaard, Helle Holm, Ditlev, Sisse B, Soegaard, Max, Poulsen, Lars, Dyring, Charlotte, Calle, Carlos Lamsfus, Knoblich, Annette, Ibáñez, Javier, Esen, Meral, Deloron, Philippe, Ndam, Nicaise, Issifou, Saadou, Houard, Sophie, Howard, Randall F, Reed, Steven G, Leroy, Odile, Luty, Adrian J F, Theander, Thor G, Kremsner, Peter G, Salanti, Ali, Nielsen, Morten A

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Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding von Wang, Kaituo, Dagil, Robert, Lavstsen, Thomas, Misra, Sandeep K., Spliid, Charlotte B., Wang, Yong, Gustavsson, Tobias, Sandoval, Daniel R., Vidal-Calvo, Elena Ethel, Choudhary, Swati, Agerbaek, Mette Ø, Lindorff-Larsen, Kresten, Nielsen, Morten A., Theander, Thor G., Sharp, Joshua S., Clausen, Thomas Mandel, Gourdon, Pontus, Salanti, Ali

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The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner von Agerbæk, Mette Ø., Bang-Christensen, Sara R., Yang, Ming-Hsin, Clausen, Thomas M., Pereira, Marina A., Sharma, Shreya, Ditlev, Sisse B., Nielsen, Morten A., Choudhary, Swati, Gustavsson, Tobias, Sorensen, Poul H., Meyer, Tim, Propper, David, Shamash, Jonathan, Theander, Thor G., Aicher, Alexandra, Daugaard, Mads, Heeschen, Christopher, Salanti, Ali

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Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquer von Rask, Thomas S, Hansen, Daniel A, Theander, Thor G, Gorm Pedersen, Anders, Lavstsen, Thomas

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Mosaic and cocktail capsid-virus-like particle vaccines for induction of antibodies against the EPCR-binding CIDRα1 domain of PfEMP1 von Riedmiller, Ilary, Fougeroux, Cyrielle, Jensen, Rasmus W, Kana, Ikhlaq H, Sander, Adam F, Theander, Thor G, Lavstsen, Thomas, Turner, Louise

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Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein von Salanti, Ali, Clausen, Thomas M., Agerbæk, Mette Ø., Al Nakouzi, Nader, Dahlbäck, Madeleine, Oo, Htoo Z., Lee, Sherry, Gustavsson, Tobias, Rich, Jamie R., Hedberg, Bradley J., Mao, Yang, Barington, Line, Pereira, Marina A., LoBello, Janine, Endo, Makoto, Fazli, Ladan, Soden, Jo, Wang, Chris K., Sander, Adam F., Dagil, Robert, Thrane, Susan, Holst, Peter J., Meng, Le, Favero, Francesco, Weiss, Glen J., Nielsen, Morten A., Freeth, Jim, Nielsen, Torsten O., Zaia, Joseph, Tran, Nhan L., Trent, Jeff, Babcook, John S., Theander, Thor G., Sorensen, Poul H., Daugaard, Mads

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PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum von Jiang, Lubin, Mu, Jianbing, Zhang, Qingfeng, Ni, Ting, Srinivasan, Prakash, Rayavara, Kempaiah, Yang, Wenjing, Turner, Louise, Lavstsen, Thomas, Theander, Thor G., Peng, Weiqun, Wei, Guiying, Jing, Qingqing, Wakabayashi, Yoshiyuki, Bansal, Abhisheka, Luo, Yan, Ribeiro, José M. C., Scherf, Artur, Aravind, L., Zhu, Jun, Zhao, Keji, Miller, Louis H.

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Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children von Lavstsen, Thomas, Turner, Louise, Saguti, Fredy, Magistrado, Pamela, Rask, Thomas S, Jespersen, Jakob S, Wang, Christian W, Berger, Sanne S, Baraka, Vito, Marquard, Andrea M, Seguin-Orlando, Andaine, Willerslev, Eske, Gilbert, M. Thomas P, Lusingu, John, Theander, Thor G

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Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like display von Singh, Susheel K, Thrane, Susan, Janitzek, Christoph M, Nielsen, Morten A, Theander, Thor G, Theisen, Michael, Salanti, Ali, Sander, Adam F

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A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA von Thrane, Susan, Janitzek, Christoph M, Agerbæk, Mette Ø, Ditlev, Sisse B, Resende, Mafalda, Nielsen, Morten A, Theander, Thor G, Salanti, Ali, Sander, Adam F

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The specificity of the malarial VAR2CSA protein for chondroitin sulfate depends on 4-O-sulfation and ligand accessibility von Spliid, Charlotte B., Toledo, Alejandro Gomez, Sanderson, Patience, Mao, Yang, Gatto, Francesco, Gustavsson, Tobias, Choudhary, Swati, Saldanha, Ana L., Vogelsang, Rasmus P., Gögenur, Ismail, Theander, Thor G., Leach, Franklin E., Amster, I. Jonathan, Esko, Jeffrey D., Salanti, Ali, Clausen, Thomas Mandel

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Bispecific T cell-engager targeting oncofetal chondroitin sulfate induces complete tumor regression and protective immune memory in mice von Skeltved, Nanna, Nordmaj, Mie A, Berendtsen, Nicolai T, Dagil, Robert, Stormer, Emilie M R, Al-Nakouzi, Nader, Jiang, Ke, Aicher, Alexandra, Heeschen, Christopher, Gustavsson, Tobias, Choudhary, Swati, Gögenur, Ismail, Christensen, Jan P, Theander, Thor G, Daugaard, Mads, Salanti, Ali, Nielsen, Morten A

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Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains von Jespersen, Jakob S, Wang, Christian W, Mkumbaye, Sixbert I, Minja, Daniel TR, Petersen, Bent, Turner, Louise, Petersen, Jens EV, Lusingu, John PA, Theander, Thor G, Lavstsen, Thomas

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A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodies von Bengtsson, Anja, Joergensen, Louise, Rask, Thomas S, Olsen, Rebecca W, Andersen, Marianne A, Turner, Louise, Theander, Thor G, Hviid, Lars, Higgins, Matthew K, Craig, Alister, Brown, Alan, Jensen, Anja T R

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Virus-like particle display of HER2 induces potent anti-cancer responses von Palladini, Arianna, Thrane, Susan, Janitzek, Christoph M., Pihl, Jessica, Clemmensen, Stine B., de Jongh, Willem Adriaan, Clausen, Thomas M., Nicoletti, Giordano, Landuzzi, Lorena, Penichet, Manuel L., Balboni, Tania, Ianzano, Marianna L., Giusti, Veronica, Theander, Thor G., Nielsen, Morten A., Salanti, Ali, Lollini, Pier-Luigi, Nanni, Patrizia, Sander, Adam F.

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The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccin... von Nielsen, Morten A, Resende, Mafalda, de Jongh, Willem A, Ditlev, Sisse B, Mordmüller, Benjamin, Houard, Sophie, Ndam, Nicaise Tuikue, Agerbæk, Mette Ø, Hamborg, Mette, Massougbodji, Achille, Issifou, Saddou, Strøbæk, Anette, Poulsen, Lars, Leroy, Odile, Kremsner, Peter G, Chippaux, Jean-Philippe, Luty, Adrian J F, Deloron, Philippe, Theander, Thor G, Dyring, Charlotte, Salanti, Ali

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