Carcinoma-associated fibroblasts: orchestrating the composition of malignancy von Gascard, Philippe, Tlsty, Thea D

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Stromal directives can control cancer von Tlsty, Thea D, Gascard, Philippe

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Tumor stroma and regulation of cancer development von Tlsty, Thea D, Coussens, Lisa M

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A hybrid epithelial-mesenchymal transition program enables basal epithelial cells to bypass stress-induced stasis and contributes to a metaplastic breast cancer progenitor state von Caruso, Joseph A, Chen-Tanyolac, Chira, Tlsty, Thea D

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Studying Progression from Chronic Injury to Esophageal Adenocarcinoma von Tlsty, Thea D

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Metastatic State of Cancer Cells May Be Indicated by Adhesion Strength von Fuhrmann, Alexander, Banisadr, Afsheen, Beri, Pranjali, Tlsty, Thea D., Engler, Adam J.

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Integrative analysis of 111 reference human epigenomes von Kundaje, Anshul, Meuleman, Wouter, Ernst, Jason, Bilenky, Misha, Yen, Angela, Heravi-Moussavi, Alireza, Kheradpour, Pouya, Zhang, Zhizhuo, Wang, Jianrong, Ziller, Michael J., Amin, Viren, Whitaker, John W., Schultz, Matthew D., Ward, Lucas D., Sarkar, Abhishek, Quon, Gerald, Sandstrom, Richard S., Eaton, Matthew L., Wu, Yi-Chieh, Pfenning, Andreas R., Wang, Xinchen, Claussnitzer, Melina, Liu, Yaping, Coarfa, Cristian, Harris, R. Alan, Shoresh, Noam, Epstein, Charles B., Gjoneska, Elizabeta, Leung, Danny, Xie, Wei, Hawkins, R. David, Lister, Ryan, Hong, Chibo, Gascard, Philippe, Mungall, Andrew J., Moore, Richard, Chuah, Eric, Tam, Angela, Canfield, Theresa K., Hansen, R. Scott, Kaul, Rajinder, Sabo, Peter J., Bansal, Mukul S., Carles, Annaick, Dixon, Jesse R., Farh, Kai-How, Feizi, Soheil, Karlic, Rosa, Kim, Ah-Ram, Kulkarni, Ashwinikumar, Li, Daofeng, Lowdon, Rebecca, Elliott, GiNell, Mercer, Tim R., Neph, Shane J., Onuchic, Vitor, Polak, Paz, Rajagopal, Nisha, Ray, Pradipta, Sallari, Richard C., Siebenthall, Kyle T., Sinnott-Armstrong, Nicholas A., Stevens, Michael, Thurman, Robert E., Wu, Jie, Zhang, Bo, Zhou, Xin, Beaudet, Arthur E., Boyer, Laurie A., De Jager, Philip L., Farnham, Peggy J., Fisher, Susan J., Haussler, David, Jones, Steven J. M., Li, Wei, Marra, Marco A., McManus, Michael T., Sunyaev, Shamil, Thomson, James A., Tlsty, Thea D., Tsai, Li-Huei, Wang, Wei, Waterland, Robert A., Zhang, Michael Q., Chadwick, Lisa H., Bernstein, Bradley E., Costello, Joseph F., Ecker, Joseph R., Hirst, Martin, Meissner, Alexander, Milosavljevic, Aleksandar, Ren, Bing, Stamatoyannopoulos, John A., Wang, Ting, Kellis, Manolis

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Breast Fibroblasts Modulate Early Dissemination, Tumorigenesis, and Metastasis through Alteration of Extracellular Matrix Characteristics von Dumont, Nancy, Liu, Bob, DeFilippis, Rosa Anna, Chang, Hang, Rabban, Joseph T, Karnezis, Anthony N, Tjoe, Judy A, Marx, James, Parvin, Bahram, Tlsty, Thea D

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Rare somatic cells from human breast tissue exhibit extensive lineage plasticity von Roy, Somdutta, Gascard, Philippe, Dumont, Nancy, Zhao, Jianxin, Pan, Deng, Petrie, Sarah, Margeta, Marta, Tlsty, Thea D.

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Tumor microenvironment and progression von Dvorak, Harold F., Weaver, Valerie M., Tlsty, Thea D., Bergers, Gabriele

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Cell motility and drug gradients in the emergence of resistance to chemotherapy von Wua, Amy, Loutherback, Kevin, Lambert, Guillaume, Estévez-Salmerón, Luis, Tlsty, Thea D., Austine, Robert H., Sturm, James C.

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An analogy between the evolution of drug resistance in bacterial communities and malignant tissues von Tlsty, Thea D, Austin, Robert H, Lambert, Guillaume, Estévez-Salmeron, Luis, Oh, Steve, Liao, David, Emerson, Beverly M

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Biomarker Expression and Risk of Subsequent Tumors After Initial Ductal Carcinoma In Situ Diagnosis von Kerlikowske, Karla, Molinaro, Annette M., Gauthier, Mona L., Berman, Hal K., Waldman, Fred, Bennington, James, Sanchez, Henry, Jimenez, Cynthia, Stewart, Kim, Chew, Karen, Ljung, Britt-Marie, Tlsty, Thea D.

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Apposition of Fibroblasts With Metaplastic Gastric Cells Promotes Dysplastic Transition von Lee, Su-Hyung, Contreras Panta, Ela W., Gibbs, David, Won, Yoonkyung, Min, Jimin, Zhang, Changqing, Roland, Joseph T., Hong, Se-Hoon, Sohn, Yoojin, Krystofiak, Evan, Jang, Bogun, Ferri, Lorenzo, Sangwan, Veena, Ragoussis, Jiannis, Camilleri-Broët, Sophie, Caruso, Joseph, Chen-Tanyolac, Chira, Strasser, Michael, Gascard, Philippe, Tlsty, Thea D., Huang, Sui, Choi, Eunyoung, Goldenring, James R.

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Coordinate Transcriptional and Translational Repression of p53 by TGF-β1 Impairs the Stress Response von López-Díaz, Fernando J., Gascard, Philippe, Balakrishnan, Sri Kripa, Zhao, Jianxin, del Rincon, Sonia V., Spruck, Charles, Tlsty, Thea D., Emerson, Beverly M.

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Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers von Dumont, Nancy, Wilson, Matthew B, Crawford, Yongping G, Reynolds, Paul A, Sigaroudinia, Mahvash, Tlsty, Thea D

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A framework for advancing our understanding of cancer-associated fibroblasts von Sahai, Erik, Astsaturov, Igor, Cukierman, Edna, DeNardo, David G., Egeblad, Mikala, Evans, Ronald M., Fearon, Douglas, Greten, Florian R., Hingorani, Sunil R., Hunter, Tony, Hynes, Richard O., Jain, Rakesh K., Janowitz, Tobias, Jorgensen, Claus, Kimmelman, Alec C., Kolonin, Mikhail G., Maki, Robert G., Powers, R. Scott, Puré, Ellen, Ramirez, Daniel C., Scherz-Shouval, Ruth, Sherman, Mara H., Stewart, Sheila, Tlsty, Thea D., Tuveson, David A., Watt, Fiona M., Weaver, Valerie, Weeraratna, Ashani T., Werb, Zena

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Intermediate DNA methylation is a conserved signature of genome regulation von Elliott, GiNell, Hong, Chibo, Xing, Xiaoyun, Zhou, Xin, Li, Daofeng, Coarfa, Cristian, Bell, Robert J.A., Maire, Cecile L., Ligon, Keith L., Sigaroudinia, Mahvash, Gascard, Philippe, Tlsty, Thea D., Harris, R. Alan, Schalkwyk, Leonard C., Bilenky, Misha, Mill, Jonathan, Farnham, Peggy J., Kellis, Manolis, Marra, Marco A., Milosavljevic, Aleksandar, Hirst, Martin, Stormo, Gary D., Wang, Ting, Costello, Joseph F.

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Loss of PPARγ activity characterizes early protumorigenic stromal reprogramming and dictates the therapeutic window of opportunity von Caruso, Joseph A, Wang, Xianhong, Murrow, Lyndsay M, Rodriguez, Carlos Ivan, Chen-Tanyolac, Chira, Vu, Lisa, Chen, Yunn-Yi, Gascard, Philippe, Gartner, Zev J, Kerlikowske, Karla, Tlsty, Thea D

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Higher Nodal expression is often associated with poorer survival in patients diagnosed with melanoma and treated with anti-PD1 therapy von Gascard, Philippe D, Wang, Xianhong, Nosrati, Mehdi, Kim, Kevin B, Kashani-Sabet, Mohammed, Tlsty, Thea D, Leong, Stanley P, Hendrix, Mary J C

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