Assessing the performance of QSP models: biology as the driver for validation von Singh, Fulya Akpinar, Afzal, Nasrin, Smithline, Shepard J., Thalhauser, Craig J.

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High degree of heterogeneity in Alzheimer's disease progression patterns von Komarova, Natalia L, Thalhauser, Craig J

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A Flexible Approach for Context‐Dependent Assessment of Quantitative Systems Pharmacology Models von Ramanujan, Saroja, Chan, Jason R., Friedrich, Christina M., Thalhauser, Craig J.

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Immunogenicity in Clinical Practice and Drug Development: When is it Significant? von Shakhnovich, Valentina, Meibohm, Bernd, Rosenberg, Amy, Kierzek, Andrzej M., Hasenkamp, Rachel, Funk, Ryan S., Thalhauser, Craig J., Graaf, Piet H., Wang, Yow‐Ming C., Hamuro, Lora

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Advancing cancer drug development with mechanistic mathematical modeling: bridging the gap between theory and practice von Kulesza, Alexander, Couty, Claire, Lemarre, Paul, Thalhauser, Craig J., Cao, Yanguang

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Signal response sensitivity in the yeast mitogen-activated protein kinase cascade von Thalhauser, Craig J, Komarova, Natalia L

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Calculating stage duration statistics in multistage diseases von Komarova, Natalia L, Thalhauser, Craig J

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An asymptotic description of a basic FcRn-regulated clearance mechanism and its implications for PBPK modelling of large antibodies von Kátai, Csaba B., Smithline, Shepard J., Thalhauser, Craig J., Bosgra, Sieto, Elassaiss-Schaap, Jeroen

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Selection in spatial stochastic models of cancer: migration as a key modulator of fitness von Thalhauser, Craig J, Lowengrub, John S, Stupack, Dwayne, Komarova, Natalia L

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QSP Toolbox: Computational Implementation of Integrated Workflow Components for Deploying Multi-Scale Mechanistic Models von Cheng, Yougan, Thalhauser, Craig J., Smithline, Shepard, Pagidala, Jyotsna, Miladinov, Marko, Vezina, Heather E., Gupta, Manish, Leil, Tarek A., Schmidt, Brian J.

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A Survey of Software Tool Utilization and Capabilities for Quantitative Systems Pharmacology: What We Have and What We Need von Ermakov, Sergey, Schmidt, Brian J., Musante, Cynthia J., Thalhauser, Craig J.

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Evaluating a Multiscale Mechanistic Model of the Immune System to Predict Human Immunogenicity for a Biotherapeutic in Phase 1 von Hamuro, Lora, Tirucherai, Giridhar S., Crawford, Sean M., Nayeem, Akbar, Pillutla, Renuka C., DeSilva, Binodh S., Leil, Tarek A., Thalhauser, Craig J.

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Alzheimer's disease: rapid and slow progression von Thalhauser, Craig J., Komarova, Natalia L.

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A Quantitative Systems Pharmacology Consortium Approach to Managing Immunogenicity of Therapeutic Proteins von Kierzek, Andrzej M., Hickling, Timothy P., Figueroa, Isabel, Kalvass, J. Cory, Nijsen, Marjoleen, Mohan, Krithika, Veldman, Geertruida M., Yamada, Akihiro, Sayama, Hiroyuki, Yokoo, Sachiko, Gulati, Abhishek, Dhanikula, Renu S., Gokemeijer, Jochem, Leil, Tarek A., Thalhauser, Craig J., Giorgi, Mario, Swat, Maciej J., Chelliah, Vijayalakshmi, Small, Ben G., Benson, Neil, Walker, Michael, Gadkar, Kapil, Quarmby, Valerie, Deng, Rong, Ferrante, Andrea, Dickinson, Gemma L., Van Der Walt, Jan‐Stefan, Zhou, Lian, Chen, Xiaoying, Jones, Hannah M., Narula, Jatin, Tourdot, Sophie, Lavé, Thierry, Ribba, Benjamin, Graaf, Piet H.

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Specificity and Robustness of the Mammalian MAPK-IEG Network von Thalhauser, Craig J., Komarova, Natalia L.

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Explicit Separation of Growth and Motility in a New Tumor Cord Model von Thalhauser, Craig J, Sankar, Tejas, Preul, Mark C, Kuang, Yang

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Identification of Histidine Tautomers in Proteins by 2D 1H/13Cδ2 One-Bond Correlated NMR von Sudmeier, James L, Bradshaw, Elizabeth M, Haddad, Kristin E. Coffman, Day, Regina M, Thalhauser, Craig J, Bullock, Peter A, Bachovchin, William W

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Tautomerism, acid‐base equilibria, and H‐bonding of the six histidines in subtilisin BPN′ by NMR von Day, Regina M., Thalhauser, Craig J., Sudmeier, James L., Vincent, Matthew P., Torchilin, Ekaterina V., Sanford, David G., Bachovchin, Christopher W., Bachovchin, William W.

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Abstract 846: Utilizing quantitative systems pharmacology (QSP) model to understand cytokine release syndrome (CRS) following administration of epcoritamab in DLBCL patients von Afzal, Nasrin, Li, Tommy, Chiu, Christopher, Sacchi, Mariana, Gupta, Manish, Xu, Steven, Thalhauser, Craig J.

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A Flexible Approach for Context-Dependent Assessment of Quantitative Systems Pharmacology Models (vol 86, pg 340, 2020) von Ramanujan, Saroja, Chan, Jason R., Friedrich, Christina M., Thalhauser, Craig J.

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