An autoinhibitory helix in the C-terminal region of phospholipase C-β mediates G[α.sub.q] activation von Lyon, Angeline M, Tesmer, Valerie M, Dhamsania, Vishan D, Thai, David M, Gutierrez, Joanne, Chowdhury, Shoaib, Suddala, Krishna C, Northup, John K, Tesmer, John J.G

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A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas von Soragni, Alice, Janzen, Deanna M., Johnson, Lisa M., Lindgren, Anne G., Thai-Quynh Nguyen, Anh, Tiourin, Ekaterina, Soriaga, Angela B., Lu, Jing, Jiang, Lin, Faull, Kym F., Pellegrini, Matteo, Memarzadeh, Sanaz, Eisenberg, David S.

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Combination Antifungal Therapy for Cryptococcal Meningitis von Day, Jeremy N, Chau, Tran T.H, Wolbers, Marcel, Mai, Pham P, Dung, Nguyen T, Mai, Nguyen H, Phu, Nguyen H, Nghia, Ho D, Phong, Nguyen D, Thai, Cao Q, Thai, Le H, Chuong, Ly V, Sinh, Dinh X, Duong, Van A, Hoang, Thu N, Diep, Pham T, Campbell, James I, Sieu, Tran P.M, Baker, Stephen G, Chau, Nguyen V.V, Hien, Tran T, Lalloo, David G, Farrar, Jeremy J

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Mutations in TSC1, TSC2, and MTOR Are Associated with Response to Rapalogs in Patients with Metastatic Renal Cell Carcinoma von Kwiatkowski, David J, Choueiri, Toni K, Fay, André P, Rini, Brian I, Thorner, Aaron R, de Velasco, Guillermo, Tyburczy, Magdalena E, Hamieh, Lana, Albiges, Laurence, Agarwal, Neeraj, Ho, Thai H, Song, Jiaxi, Pignon, Jean-Christophe, Barrios, Pablo M, Michaelson, M Dror, Van Allen, Eliezer, Krajewski, Katherine M, Porta, Camillo, Pal, Sumanta, Bellmunt, Joaquim, McDermott, David F, Heng, Daniel Y C, Gray, Kathryn P, Signoretti, Sabina

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STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment von Koyama, Shohei, Akbay, Esra A, Li, Yvonne Y, Aref, Amir R, Skoulidis, Ferdinandos, Herter-Sprie, Grit S, Buczkowski, Kevin A, Liu, Yan, Awad, Mark M, Denning, Warren L, Diao, Lixia, Wang, Jing, Parra-Cuentas, Edwin R, Wistuba, Ignacio I, Soucheray, Margaret, Thai, Tran, Asahina, Hajime, Kitajima, Shunsuke, Altabef, Abigail, Cavanaugh, Jillian D, Rhee, Kevin, Gao, Peng, Zhang, Haikuo, Fecci, Peter E, Shimamura, Takeshi, Hellmann, Matthew D, Heymach, John V, Hodi, F Stephen, Freeman, Gordon J, Barbie, David A, Dranoff, Glenn, Hammerman, Peter S, Wong, Kwok-Kin

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Regulation of the Germinal Center Response by MicroRNA-155 von Thai, To-Ha, Calado, Dinis Pedro, Casola, Stefano, Ansel, K. Mark, Xiao, Changchun, Xue, Yingzi, Murphy, Andrew, Frendewey, David, Valenzuela, David, Kutok, Jeffery L, Schmidt-Supprian, Marc, Rajewsky, Nikolaus, Yancopoulos, George, Rao, Anjana, Rajewsky, Klaus

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Identification of Novel Long Noncoding RNAs Underlying Vertebrate Cardiovascular Development von Kurian, Leo, Aguirre, Aitor, Sancho-Martinez, Ignacio, Benner, Christopher, Hishida, Tomoaki, Nguyen, Thai B, Reddy, Pradeep, Nivet, Emmanuel, Krause, Marie N, Nelles, David A, Esteban, Concepcion Rodriguez, Campistol, Josep M, Yeo, Gene W, Izpisua Belmonte, Juan Carlos

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Androgen Receptor Variant AR-V9 Is Coexpressed with AR-V7 in Prostate Cancer Metastases and Predicts Abiraterone Resistance von Kohli, Manish, Ho, Yeung, Hillman, David W, Van Etten, Jamie L, Henzler, Christine, Yang, Rendong, Sperger, Jamie M, Li, Yingming, Tseng, Elizabeth, Hon, Ting, Clark, Tyson, Tan, Winston, Carlson, Rachel E, Wang, Liguo, Sicotte, Hugues, Thai, Ho, Jimenez, Rafael, Huang, Haojie, Vedell, Peter T, Eckloff, Bruce W, Quevedo, Jorge F, Pitot, Henry C, Costello, Brian A, Jen, Jin, Wieben, Eric D, Silverstein, Kevin A T, Lang, Joshua M, Wang, Liewei, Dehm, Scott M

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Quantitative Spatial Profiling of PD-1/PD-L1 Interaction and HLA-DR/IDO-1 Predicts Improved Outcomes of Anti-PD-1 Therapies in Metastatic Melanoma von Johnson, Douglas B, Bordeaux, Jennifer, Kim, Ju Young, Vaupel, Christine, Rimm, David L, Ho, Thai H, Joseph, Richard W, Daud, Adil I, Conry, Robert M, Gaughan, Elizabeth M, Hernandez-Aya, Leonel F, Dimou, Anastasios, Funchain, Pauline, Smithy, James, Witte, John S, McKee, Svetlana B, Ko, Jennifer, Wrangle, John M, Dabbas, Bashar, Tangri, Shabnam, Lameh, Jelveh, Hall, Jeffrey, Markowitz, Joseph, Balko, Justin M, Dakappagari, Naveen

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Culture, distress, and oxytocin receptor polymorphism (OXTR) interact to influence emotional support seeking von Kim, Heejung S., Sherman, David K., Sasaki, Joni Y., Xu, Jun, Chu, Thai Q., Ryu, Chorong, Suh, Eunkook M., Graham, Kelsey, Taylor, Shelley E.

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Population-level effectiveness of rapid, targeted, high-coverage roll-out of HIV pre-exposure prophylaxis in men who have sex with men: the EPIC-NSW prospective cohort study von Grulich, Andrew E, Guy, Rebecca, Amin, Janaki, Jin, Fengyi, Selvey, Christine, Holden, Jo, Schmidt, Heather-Marie A, Zablotska, Iryna, Price, Karen, Whittaker, Bill, Chant, Kerry, Cooper, Craig, McGill, Scott, Telfer, Barbara, Yeung, Barbara, Levitt, Gesalit, Ogilvie, Erin E, Dharan, Nila J, Hammoud, Mohamed A, Vaccher, Stefanie, Watchirs-Smith, Lucy, McNulty, Anna, Smith, David J, Allen, Debra M, Baker, David, Bloch, Mark, Bopage, Rohan I, Brown, Katherine, Carr, Andrew, Carmody, Christopher J, Collins, Kym L, Finlayson, Robert, Foster, Rosalind, Jackson, Eva Y, Lewis, David A, Lusk, Josephine, O'Connor, Catherine C, Ryder, Nathan, Vlahakis, Emanuel, Read, Phillip, Cooper, David A, Smith, Don, Ooi, Catriona, Martin, Sarah, Soo, Tuck Meng, Templeton, David, Townson, David, Forssman, Brad, Doong, Nick, Han Thai, Gai, Anderson, Ben, MacLeod, Hugh, Parkhill, Nicolas

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Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia von Hysi, Pirro G., Choquet, Hélène, Khawaja, Anthony P., Wojciechowski, Robert, Tedja, Milly S., Yin, Jie, Simcoe, Mark J., Patasova, Karina, Mahroo, Omar A., Thai, Khanh K., Cumberland, Phillippa M., Melles, Ronald B., Verhoeven, Virginie J. M., Vitart, Veronique, Segre, Ayellet, Stone, Richard A., Wareham, Nick, Hewitt, Alex W., Mackey, David A., Klaver, Caroline C. W., MacGregor, Stuart, Khaw, Peng T., Foster, Paul J., Guggenheim, Jeremy A., Rahi, Jugnoo S., Jorgenson, Eric, Hammond, Christopher J.

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Suppression of STING Associated with LKB1 Loss in KRAS-Driven Lung Cancer von Kitajima, Shunsuke, Ivanova, Elena, Guo, Sujuan, Yoshida, Ryohei, Campisi, Marco, Sundararaman, Shriram K, Tange, Shoichiro, Mitsuishi, Yoichiro, Thai, Tran C, Masuda, Sayuri, Piel, Brandon P, Sholl, Lynette M, Kirschmeier, Paul T, Paweletz, Cloud P, Watanabe, Hideo, Yajima, Mamiko, Barbie, David A

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Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer von Kim, Jaegil, Bellmunt, Joaquim, Cherniack, Andrew D., Hinoue, Toshinori, Hoadley, Katherine A., Gibb, Ewan A., Shukla, Sachet A., Sanchez-Vega, Francisco, Reuter, Victor E., Sadeghi, Sara, Pedamallu, Chandra Sekhar, Lu, Yiling, Klimczak, Leszek J., Zhang, Jiexin, Choo, Caleb, Leraas, Kristen M., Lichtenberg, Tara M., Schultz, Nicholaus, Getz, Gad, Mills, Gordon B., Al-Ahmadie, Hikmat, Alexopoulou, Iakovina, Ally, Adrian, Beaver, Allison, Bellmunt, Joaquim, Boice, Lori, Bootwalla, Moiz S., Bowen, Jay, Brooks, Denise, Broom, Bradley M., Bshara, Wiam, Bullman, Susan, Burks, Eric, Carvalho, Benilton S., Carvalho, Andre L., Castro, Mauro A.A., Chagas, Vinicius S., Cherniack, Andrew D., Cortessis, Victoria K., Czerniak, Bogdan A., Daneshmand, Siamak, Dhalla, Noreen, Egea, Sophie C., Engel, Jay, Felau, Ina, Gastier-Foster, Julie M., Getz, Gad, Gordenin, Dmitry A., Hansel, Donna E., Harr, Jodi, Hartmann, Arndt, Hinoue, Toshinori, Jones, Steven J.M., Kahnoski, Richard J., Kasaian, Katayoon, Lai, Phillip H., Lane, Brian R., Liu, Jia, Lolla, Laxmi, Lotan, Yair, Lu, Yiling, Lucchesi, Fabiano R., Mallery, David, Marra, Marco A., Mills, Gordon B., Mungall, Karen L., Ojesina, Akinyemi I., Parekh, Dipen J., Sekhar Pedamallu, Chandra, Pihl, Todd, Rathmell, W. Kimryn, Robertson, A. Gordon, Sadeghi, Sara, Saller, Charles, Salner, Andrew, Sanchez-Vega, Francisco, Scapulatempo-Neto, Cristovam, Schuckman, Anne K., Shukla, Sachet A., Simko, Jeff, Sipahimalani, Payal, Sorcini, Andrea, Stoehr, Robert, Su, Xiaoping, Tarnuzzer, Roy, Thiessen, Nina, Thorne, Leigh, Tse, Kane, Wach, Sven, Wang, Zhining, Weinstein, John N., Wise, Lisa, Wong, Tina, Wu, Ye, Zach, Leigh Anne, Zenklusen, Jean C., Zhang, Jiashan (Julia), Zhang, Jiexin, Zwarthoff, Ellen C., Weinstein, John N.

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Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity von Mahadevan, Navin R, Knelson, Erik H, Wolff, Jacquelyn O, Vajdi, Amir, Saigí, Maria, Campisi, Marco, Hong, Deli, Thai, Tran C, Piel, Brandon, Han, Saemi, Reinhold, Bruce B, Duke-Cohan, Jonathan S, Poitras, Michael J, Taus, Luke J, Lizotte, Patrick H, Portell, Andrew, Quadros, Victor, Santucci, Alison D, Murayama, Takahiko, Cañadas, Israel, Kitajima, Shunsuke, Akitsu, Aoi, Fridrikh, Maya, Watanabe, Hideo, Reardon, Brendan, Gokhale, Prafulla C, Paweletz, Cloud P, Awad, Mark M, Van Allen, Eliezer M, Lako, Ana, Wang, Xi-Tao, Chen, Benjamin, Hong, Fangxin, Sholl, Lynette M, Tolstorukov, Michael Y, Pfaff, Kathleen, Jänne, Pasi A, Gjini, Evisa, Edwards, Robin, Rodig, Scott, Reinherz, Ellis L, Oser, Matthew G, Barbie, David A

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Deep and fast live imaging with two-photon scanned light-sheet microscopy von Truong, Thai V, Supatto, Willy, Koos, David S, Choi, John M, Fraser, Scott E

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Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer’s disease pathology von Mathys, Hansruedi, Peng, Zhuyu, Boix, Carles A., Victor, Matheus B., Leary, Noelle, Babu, Sudhagar, Abdelhady, Ghada, Jiang, Xueqiao, Ng, Ayesha P., Ghafari, Kimia, Kunisky, Alexander K., Mantero, Julio, Galani, Kyriaki, Lohia, Vanshika N., Fortier, Gabrielle E., Lotfi, Yasmine, Ivey, Jason, Brown, Hannah P., Patel, Pratham R., Chakraborty, Nehal, Beaudway, Jacob I., Imhoff, Elizabeth J., Keeler, Cameron F., McChesney, Maren M., Patel, Haishal H., Patel, Sahil P., Thai, Megan T., Bennett, David A., Kellis, Manolis, Tsai, Li-Huei

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Simplification to coformulated elvitegravir, cobicistat, emtricitabine, and tenofovir versus continuation of ritonavir-boosted protease inhibitor with emtricitabine and tenofovir i... von Arribas, Jose R, Dr, Pialoux, Gilles, Prof, Gathe, Joseph, MD, Di Perri, Giovanni, Prof, Reynes, Jacques, Prof, Tebas, Pablo, MD, Nguyen, Thai, MD, Ebrahimi, Ramin, MS, White, Kirsten, PhD, Piontkowsky, David, MD

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Pan-cancer analysis of whole genomes von Campbell, Peter J, Getz, Gad, Korbel, Jan O, Stuart, Joshua M, Jennings, Jennifer L, Stein, Lincoln D, Perry, Marc D

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Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture von Zhang, Qian, Sidorenko, Julia, Couvy-Duchesne, Baptiste, Marioni, Riccardo E., Wright, Margaret J., Goate, Alison M., Marcora, Edoardo, Huang, Kuan-lin, Porter, Tenielle, Laws, Simon M., Sachdev, Perminder S., Mather, Karen A., Armstrong, Nicola J., Thalamuthu, Anbupalam, Brodaty, Henry, Yengo, Loic, Yang, Jian, Wray, Naomi R., McRae, Allan F., Visscher, Peter M.

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