Abstract 1754: First in class orally bioavailable BETBRD degraders von Abbineni, Chandrasekhar, Jaleel, Mahaboobi, Mukherjee, Subhendu, Marappan, Sivapriya, Tiwari, Nirbhay Kumar, Samiulla, DS, Aravind, AB, Kumar, Naveen R, Bansal, Indu, Reddy, Raghurami B, Bandaru, NVM Rao, Srinivas, Akhila, Maben, Janith Mary, Tgore, Suraj, Kumar, Avainash, Nankar, Rakesh P., Naik, Chandranath D., Antony, Thomas, Nellore, Kavitha, Giri, Sanjeev, Daginakatte, Girish, Chelur, Shekar, Törmäkangas, Olli, Wohlfahrt, Gerd, Björkman, Mari, Mattila, Elina, Ravanti, Laura, Moilanen, Anu, Ramachandra, Murali, Samajdar, Susanta

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Abstract 1753: Targeting cancer with selective cbp/p300 bromodomain inhibitors von Jaleel, Mahaboobi, Senaiar, Ramesh S., Abbineni, Chandrasekhar, Renukappa, Girish A., Mukherjee, Subhendu, Marappan, Sivapriya, Samiulla, DS, Aravind, AB, Kumar, Naveen R., Reddy, Venkata Siva N., Babu, Asha, Srinivas, Akhila P., Yadlapalli, Prasad, Tgore, Suraj, NR, Raghavendra, Naik, Chandranath D., Giri, Sanjeev, Antony, Thomas, Nellore, Kavitha, Chelur, Shekar, Daginakatte, Girish, Ravanti, laura, Myllymäki, Mikko, Wohlfahrt, Gerd, Mattila, Elina, Karlsson, Stefan, Björkman, Mari, Riikonen, Reetta, Ikonen, Tarja, Leimu, Laura, Mälmström, Chira, Korjamo, Timo, Moilanen, Anu, Ramachandra, Murali, Samajdar, Susanta

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Abstract 3844: Anti-tumor efficacy of SMARCA degraders in pre-clinical models of cancer von Satyam, Leena Khare, Sasmal, Sanjita, Pothuganti, Manoj K., M.R., Sreevidya, Ettam, Ashokk, Nunna, Sireesha, Roshaiah, Marla, Chithaluru, Shankaraiah, Pallepati, Rangarao, Pawar, Amitkumar A., Narukulla, Leela P., Sripathi, Raghunadh A., Tgore, Suraj, Nankar, Rakesh P., KB, Charamanna, S, Nagesh Gowda, Aithal, Kiran, DS, Samiulla, Mukherjee, Subhendu, Chelur, Shekar, Nellore, Kavitha, Daginakatte, Girish, Ramachandra, Murali, Samajdar, Susanta

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Abstract 4418: Pharmacological characterization of a preclinical candidate covalently inhibiting CDK12 von Poddutoori, Ramulu, Rajagopalan, Sujatha, Mukherjee, Subhendu, Marappan, Sivapriya, D. S., Samiulla, Sivakumar, Sasirekha, Nayak, Shilpa S, M V, Ravindra, TS, Devaraja, Kondela, Srinivas, Tgore, Suraj, Dhudashiya, Amit A, K. B, Charamanna, A B, Aravind, A, Amith, S, Pavithra, Pathange, Hema Sankar, Antony, Thomas, Jaleel, Mahaboobi, Giri, Sanjeev, Daginakatte, Girish, Nellore, Kavitha, Chelur, Shekar, Ramachandra, Murali, Samajdar, Susanta

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Abstract 2384: Preclinical evaluation of PD and efficacy of novel potent selective and orally bioavailable CDK12 covalent inhibitors in TNBC model von Poddutoori, Ramulu, Rajagopalan, Sujatha, Mukherjee, Subhendu, Marappan, Sivapriya, S, Samiulla D, Sivakumar, Sasirekha, Nayak, Shilpa S., V, Ravindra M., Murtuza, Hadianawala, S, Devaraja T., Kondela, Srinivas, Tgore, Suraj, Dhudashiya, Amit A., B, Charamanna K., Antony, Thomas, Daginakatte, Girish, Giri, Sanjeev, Chelur, Shekar, Ramachandra, Murali, Pandit, Chetan, Samajdar, Susanta

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Abstract B172: Potent anti-tumor activity of a selective and orally bioavailable reversible covalent CDK12 inhibitor von Khare, Leena, Poddutoori, Ramulu, Mukherjee, Subhendu, DS, Samiulla, TS, Devaraja, Marappan, Sivapriya, Nayak, Shilpa, Sivakumar, Sasirekha, Kaza, Lakshmi, Tgore, Suraj, Dhudashiya, Amit, NR, Raghavendra, Gunnepalli, Bhargav, B, Aravind A, A, Amith, KB, Charamanna, Antony, Thomas, Nellore, Kavitha, Daginakatte, Girish, Chelur, Shekar, Giri, Sanjeev, Ramachandra, Murali, Samajdar, Susanta

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Abstract B164: Identification of a novel highly selective and orally bioavailable preclinical candidate for CDK7 covalent inhibition von Poddutoori, Ramulu, Khare Satyam, Leena, Mukherjee, Subhendu, Marappan, Sivapriya, Gopinath, Sreevalsam, KB, Charamanna, Kaza, Lakshmi Narayana, Pothuganti, Manoj Kumar, Rajagopalan, Sujatha, Sivakumar, Sasirekha, E N, Bharath, A B, Aravind, A, Amith, M V, Ravindra, Tgore, Suraj, Antony, Thomas, Pandit, Chetan, Chelur, Shekar, Daginakatte, Girish, Ramachandra, Murali, Samajdar, Susanta

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Abstract B165: Potent selective and orally bioavailable inhibition of CDK12 by novel covalent inhibitors von Poddutoori, Ramulu, Rajagopalan, Sujatha, Mukherjee, Subhendu, Marappan, Sivapriya, D S, Samiulla, Kasturi, Venkateswarlu, Sivakumar, Sasirekha, Nayak, Shilpa, M V, Ravindra, Tgore, Suraj, Dhudashiya, Amit, K B, Charamanna, Antony, Thomas, M, Mahaboobi, Giri, Sanjeev, Daginakatte, Girish C., Chelur, Shekar, Ramachandra, Murali, Pandit, Chetan, Samajdar, Susanta

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Abstract LB-317: Identification of a novel preclinical candidate for CDK7 inhibition von Satyam, Leena K., Poddutoori, Ramulu, Mukherjee, Subhendu, Marappan, Sivapriya, Gopinath, Sreevalsam, Basavaraju, Aravind, Kaza, Lakshmi Narayana, Pothuganti, Manoj Kumar, Nayak, Shilpa, C, Nandish, A, Amith, MV, Ravindra, Babu, Dabbeeru Madhu, A, Nagaraju, Tgore, Suraj, Antony, Thomas, Pandit, Chetan, Ramachandra, Murali, Chelur, Shekar, Daginakatte, Girish, Samajdar, Susanta

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