Balance of Anti-CD123 Chimeric Antigen Receptor Binding Affinity and Density for the Targeting of Acute Myeloid Leukemia von Arcangeli, Silvia, Rotiroti, Maria Caterina, Bardelli, Marco, Simonelli, Luca, Magnani, Chiara Francesca, Biondi, Andrea, Biagi, Ettore, Tettamanti, Sarah, Varani, Luca

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Fully equipped CARs to address tumor heterogeneity, enhance safety, and improve the functionality of cellular immunotherapies von Alviano, Antonio Maria, Biondi, Marta, Grassenis, Erica, Biondi, Andrea, Serafini, Marta, Tettamanti, Sarah

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Engineering tandem CD33xCD146 CAR CIK (cytokine-induced killer) cells to target the acute myeloid leukemia niche von Alberti, Gaia, Arsuffi, Corinne, Pievani, Alice, Salerno, Domenico, Mantegazza, Francesco, Dazzi, Francesco, Biondi, Andrea, Tettamanti, Sarah, Serafini, Marta

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CARs are sharpening their weapons von Pievani, Alice, Biondi, Marta, Tettamanti, Sarah, Biondi, Andrea, Dotti, Gianpietro, Serafini, Marta

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Transposon-Based CAR T Cells in Acute Leukemias: Where Are We Going? von Magnani, Chiara F., Tettamanti, Sarah, Alberti, Gaia, Pisani, Ilaria, Biondi, Andrea, Serafini, Marta, Gaipa, Giuseppe

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Functional Activity of Cytokine-Induced Killer Cells Enhanced by CAR-CD19 Modification or by Soluble Bispecific Antibody Blinatumomab von Zaninelli, Silvia, Panna, Silvia, Tettamanti, Sarah, Melita, Giusi, Doni, Andrea, D'Autilia, Francesca, Valgardsdottir, Rut, Gotti, Elisa, Rambaldi, Alessandro, Golay, Josée, Introna, Martino

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Catch me if you can: how AML and its niche escape immunotherapy von Tettamanti, Sarah, Pievani, Alice, Biondi, Andrea, Dotti, Gianpietro, Serafini, Marta

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Bone Marrow Stroma Impairs CAR-T Cell Proliferation and Function: Mechanistic Insights von Dazzi, Francesco, Savoldelli, Roberto, Pievani, Alice, Tettamanti, Sarah, Giacomini, Chiara, Kozlowska, Anna, Serafini, Marta

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Sleeping Beauty engineered CAR T cells achieve antileukemic activity without severe toxicities von Magnani, Chiara F., Gaipa, Giuseppe, Lussana, Federico, Belotti, Daniela, Gritti, Giuseppe, Napolitano, Sara, Matera, Giada, Cabiati, Benedetta, Buracchi, Chiara, Borleri, Gianmaria, Fazio, Grazia, Zaninelli, Silvia, Tettamanti, Sarah, Cesana, Stefania, Colombo, Valentina, Quaroni, Michele, Cazzaniga, Giovanni, Rovelli, Attilio, Biagi, Ettore, Galimberti, Stefania, Calabria, Andrea, Benedicenti, Fabrizio, Montini, Eugenio, Ferrari, Silvia, Introna, Martino, Balduzzi, Adriana, Valsecchi, Maria Grazia, Dastoli, Giuseppe, Rambaldi, Alessandro, Biondi, Andrea

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Combining the Expression of CD33.CAR and CXCR4 to Increase CAR-CIK Cell Homing to Bone Marrow Niche and Leukemic Stem Cell Eradication in Acute Myeloid Leukemia von Biondi, Marta, Cerina, Beatrice, Tomasoni, Chiara, Dotti, Gianpietro, Tettamanti, Sarah, Biondi, Andrea, Pievani, Alice, Serafini, Marta

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Selective homing of CAR-CIK cells to the bone marrow niche enhances control of the acute myeloid leukemia burden von Biondi, Marta, Tettamanti, Sarah, Galimberti, Stefania, Cerina, Beatrice, Tomasoni, Chiara, Piazza, Rocco, Donsante, Samantha, Bido, Simone, Perriello, Vincenzo Maria, Broccoli, Vania, Doni, Andrea, Dazzi, Francesco, Mantovani, Alberto, Dotti, Gianpietro, Biondi, Andrea, Pievani, Alice, Serafini, Marta

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Overexpression of CXCR4 Enhances the Efficacy of CAR-T Therapy for Acute Myeloid Leukemia von Biondi, Marta, Galimberti, Stefania, Cerina, Beatrice, Tomasoni, Chiara, Dotti, Gianpietro, Tettamanti, Sarah, Biondi, Andrea, Pievani, Alice, Serafini, Marta

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Targeting of acute myeloid leukaemia by cytokine‐induced killer cells redirected with a novel CD123‐specific chimeric antigen receptor von Tettamanti, Sarah, Marin, Virna, Pizzitola, Irene, Magnani, Chiara F., Giordano Attianese, Greta M. P., Cribioli, Elisabetta, Maltese, Francesca, Galimberti, Stefania, Lopez, Angel F., Biondi, Andrea, Bonnet, Dominique, Biagi, Ettore

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Manufacturing, Characterization and Anti-Tumor Activity of Allogeneic CD19-CAR Cytokine-Induced Killer (CIK) Cells Engineered with Non-Viral Sleeping Beauty Transposon System and A... von Contreras-Ruiz, Laura, Pace, Barcley, Kohnke, Dora E, Viruet, Lindsey, Adams, Melissa, Krisko, John F, Leesnitzer, Noah, Velie, Marissa, Tettamanti, Sarah, Pisani, Ilaria, Melita, Giusi, Biondi, Andrea, Rambaldi, Alessandro, Tcherepanova, Irina Y, Brentjens, Renier, Nicolette, Charles A

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New advances in leukaemia immunotherapy by the use of Chimeric Artificial Antigen Receptors (CARs): state of the art and perspectives for the near future von Biagi, Ettore, Marin, Virna, Attianese, Greta Maria Paola Giordano, Pizzitola, Irene, Tettamanti, Sarah, Cribioli, Elisabetta, Biondi, Andrea

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Targeting CD33 in Chemoresistant AML Patient-Derived Xenografts by CAR-CIK Cells Modified with an Improved SB Transposon System von Rotiroti, Maria Caterina, Buracchi, Chiara, Arcangeli, Silvia, Galimberti, Stefania, Valsecchi, Maria Grazia, Perriello, Vincenzo Maria, Rasko, Tamas, Alberti, Gaia, Magnani, Chiara Francesca, Cappuzzello, Claudia, Lundberg, Felix, Pande, Amit, Dastoli, Giuseppe, Introna, Martino, Serafini, Marta, Biagi, Ettore, Izsvák, Zsuzsanna, Biondi, Andrea, Tettamanti, Sarah

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CD123 and CD33 Co-Targeting By Balanced Signaling on CAR-CIK Cells Reduces Potential Off-Target Toxicity While Preserving the Anti-Leukemic Activity of Acute Myeloid Leukemia von Perriello, Vincenzo Maria, Rotiroti, Maria Caterina, Pisani, Ilaria, Alberti, Gaia, Pianigiani, Giulia, Rossi, Roberta, Ciaurro, Valerio, Serafini, Marta, Martelli, Maria Paola, Falini, Brunangelo, Biondi, Andrea, Tettamanti, Sarah

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Preclinical Efficacy and Safety of CD19CAR Cytokine-Induced Killer Cells Transfected with Sleeping Beauty Transposon for the Treatment of Acute Lymphoblastic Leukemia von Magnani, Chiara F, Mezzanotte, Claudia, Cappuzzello, Claudia, Bardini, Michela, Tettamanti, Sarah, Fazio, Grazia, Cooper, Laurence J N, Dastoli, Giuseppe, Cazzaniga, Giovanni, Biondi, Andrea, Biagi, Ettore

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Redirecting T cells with Chimeric Antigen Receptor (CAR) for the treatment of childhood acute lymphoblastic leukemia von Biondi, Andrea, Magnani, Chiara F., Tettamanti, Sarah, Gaipa, Giuseppe, Biagi, Ettore

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Optimization of therapeutic T cell expansion in G-Rex device and applicability to large-scale production for clinical use von Gotti, Elisa, Tettamanti, Sarah, Zaninelli, Silvia, Cuofano, Carolina, Cattaneo, Irene, Rotiroti, Maria Caterina, Cribioli, Sabrina, Alzani, Rachele, Rambaldi, Alessandro, Introna, Martino, Golay, Josée

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