Flavonols and flavones as BACE-1 inhibitors: Structure–activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features von Shimmyo, Yoshiari, Kihara, Takeshi, Akaike, Akinori, Niidome, Tetsuhiro, Sugimoto, Hachiro

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Methylcobalamin prevents mutant superoxide dismutase-1-induced motor neuron death in vitro von Ito, Shunsuke, Izumi, Yukina, Niidome, Tetsuhiro, Ono, Yuichi

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Three distinct neuroprotective functions of myricetin against glutamate-induced neuronal cell death: Involvement of direct inhibition of caspase-3 von Shimmyo, Yoshiari, Kihara, Takeshi, Akaike, Akinori, Niidome, Tetsuhiro, Sugimoto, Hachiro

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Amyloid precursor protein promotes endoplasmic reticulum stress‐induced cell death via C/EBP homologous protein‐mediated pathway von Takahashi, Keita, Niidome, Tetsuhiro, Akaike, Akinori, Kihara, Takeshi, Sugimoto, Hachiro

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Decreased proliferation of hippocampal progenitor cells in APPswe/PS1dE9 transgenic mice von Taniuchi, Nobuhiko, Niidome, Tetsuhiro, Goto, Yasuaki, Akaike, Akinori, Kihara, Takeshi, Sugimoto, Hachiro

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Rac1 inhibition negatively regulates transcriptional activity of the amyloid precursor protein gene von Wang, Pi-Lin, Niidome, Tetsuhiro, Akaike, Akinori, Kihara, Takeshi, Sugimoto, Hachiro

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Distinct mechanisms underlie distinct polyphenol-induced neuroprotection von Yazawa, Keiko, Kihara, Takeshi, Shen, Huilian, Shimmyo, Yoshiari, Niidome, Tetsuhiro, Sugimoto, Hachiro

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Integrin-associated protein promotes neuronal differentiation of neural stem/progenitor cells von Fujimura, Kazuhiko, Niidome, Tetsuhiro, Shinozuka, Yoriko, Izumi, Yasuhiko, Kihara, Takeshi, Sugimoto, Hachiro, Akaike, Akinori, Kume, Toshiaki

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Impaired muscarinic regulation of excitatory synaptic transmission in the APPswe/PS1dE9 mouse model of Alzheimer's disease von Goto, Yasuaki, Niidome, Tetsuhiro, Hongo, Haruyuki, Akaike, Akinori, Kihara, Takeshi, Sugimoto, Hachiro

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Compromised maturation of GABAergic inhibition underlies abnormal network activity in the hippocampus of epileptic Ca2+ channel mutant mice, tottering von Nakao, Akito, Miki, Takafumi, Shimono, Ken, Oka, Hiroaki, Numata, Tomohiro, Kiyonaka, Shigeki, Matsushita, Kaori, Ogura, Hiroo, Niidome, Tetsuhiro, Noebels, Jeffrey L., Wakamori, Minoru, Imoto, Keiji, Mori, Yasuo

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Roles of Nicotinic Receptors in Acetylcholinesterase Inhibitor-Induced Neuroprotection and Nicotinic Receptor Up-Regulation von Takada-Takatori, Yuki, Kume, Toshiaki, Izumi, Yasuhiko, Ohgi, Yuta, Niidome, Tetsuhiro, Fujii, Takeshi, Sugimoto, Hachiro, Akaike, Akinori

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Mechanisms of α7-nicotinic receptor up-regulation and sensitization to donepezil induced by chronic donepezil treatment von Takada-Takatori, Yuki, Kume, Toshiaki, Ohgi, Yuta, Fujii, Takeshi, Niidome, Tetsuhiro, Sugimoto, Hachiro, Akaike, Akinori

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Donepezil Potentiates Nerve Growth Factor-Induced Neurite Outgrowth in PC12 Cells von Oda, Toru, Kume, Toshiaki, Katsuki, Hiroshi, Niidome, Tetsuhiro, Sugimoto, Hachiro, Akaike, Akinori

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Neuroprotective effects of galanthamine and tacrine against glutamate neurotoxicity von Takada-Takatori, Yuki, Kume, Toshiaki, Sugimoto, Mitsuhiro, Katsuki, Hiroshi, Niidome, Tetsuhiro, Sugimoto, Hachiro, Fujii, Takeshi, Okabe, Susumu, Akaike, Akinori

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Serofendic Acid Promotes Stellation Induced by cAMP and cGMP Analogs in Cultured Cortical Astrocytes von Kume, Toshiaki, Ito, Ryo, Taguchi, Ryota, Izumi, Yasuhiko, Katsuki, Hiroshi, Niidome, Tetsuhiro, Takada-Takatori, Yuki, Sugimoto, Hachiro, Akaike, Akinori

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Single Tottering Mutations Responsible for the Neuropathic Phenotype of the P-type Calcium Channel von Wakamori, M, Yamazaki, K, Matsunodaira, H, Teramoto, T, Tanaka, I, Niidome, T, Sawada, K, Nishizawa, Y, Sekiguchi, N, Mori, E, Mori, Y, Imoto, K

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Functional and molecular interactions between Rac1 and FE65 von Wang, Pi-Lin, Niidome, Tetsuhiro, Kume, Toshiaki, Akaike, Akinori, Kihara, Takeshi, Sugimoto, Hachiro

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Mechanisms of Chronic Nicotine Treatment–Induced Enhancement of the Sensitivity of Cortical Neurons to the Neuroprotective Effect of Donepezil in Cortical Neurons von Takada-Takatori, Yuki, Kume, Toshiaki, Izumi, Yasuhiko, Niidome, Tetsuhiro, Fujii, Takeshi, Sugimoto, Hachiro, Akaike, Akinori

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Basic fibroblast growth factor promotes the generation of microtubule-associated protein 2-positive cells from microglia von Niidome, Tetsuhiro, Nonaka, Hideki, Akaike, Akinori, Kihara, Takeshi, Sugimoto, Hachiro

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Functional disorders of the sympathetic nervous system in mice lacking the α1B subunit (Cav 2.2) of N-type calcium channels von Ino, Mitsuhiro, Yoshinaga, Takashi, Wakamori, Minoru, Miyamoto, Norimasa, Takahashi, Eiki, Sonoda, Jiro, Kagaya, Takaki, Oki, Tohru, Nagasu, Takeshi, Nishizawa, Yukio, Tanaka, Isao, Imoto, Keiji, Aizawa, Shinichi, Koch, Sheryl, Schwartz, Arnold, Niidome, Tetsuhiro, Sawada, Kohei, Mori, Yasuo

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