Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis von Nieminen, Anni I, Eskelinen, Vilja M, Haikala, Heidi M, Tervonen, Topi A, Yan, Yan, Partanen, Johanna I, Klefström, Juha

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Immunoglobulin superfamily member 3 is required for the vagal neural crest cell migration and enteric neuronal network organization von Tanjore Ramanathan, Jayendrakishore, Zárybnický, Tomáš, Filppu, Pauliina, Monzo, Hector J, Monni, Outi, Tervonen, Topi A, Klefström, Juha, Kerosuo, Laura, Kuure, Satu, Laakkonen, Pirjo

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Hepsin promotes breast tumor growth signaling via the TGFβ‐EGFR axis von Belitškin, Denis, Munne, Pauliina, Pant, Shishir M., Anttila, Johanna M., Suleymanova, Ilida, Belitškina, Kati, Kirchhofer, Daniel, Janetka, James, Käsper, Taivo, Jalil, Sami, Pouwels, Jeroen, Tervonen, Topi A., Klefström, Juha

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Breaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4 von Partanen, Johanna I., Tervonen, Topi A., Klefström, Juha

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Tumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrity von Partanen, Johanna I., Tervonen, Topi A., Myllynen, Mikko, Lind, Essi, Imai, Misa, Katajisto, Pekka, Dijkgraaf, Gerrit J. P., Kovanen, Panu E., Mäkelä, Tomi P., Werb, Zena, Klefström, Juha

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Aberrant differentiation of glutamatergic cells in neocortex of mouse model for fragile X syndrome von Tervonen, Topi A, Louhivuori, Verna, Sun, Xiaohong, Hokkanen, Marie-Estelle, Kratochwil, Claudius F, Zebryk, Pawel, Castrén, Eero, Castrén, Maija L

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Hepsin regulates TGFβ signaling via fibronectin proteolysis von Belitškin, Denis, Pant, Shishir M, Munne, Pauliina, Suleymanova, Ilida, Belitškina, Kati, Hongisto, Hanna-Ala, Englund, Johanna, Raatikainen, Tiina, Klezovitch, Olga, Vasioukhin, Valeri, Li, Shuo, Wu, Qingyu, Monni, Outi, Kuure, Satu, Laakkonen, Pirjo, Pouwels, Jeroen, Tervonen, Topi A, Klefström, Juha

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Oncogenic Ras Disrupts Epithelial Integrity by Activating the Transmembrane Serine Protease Hepsin von Tervonen, Topi A., Pant, Shishir M., Belitskin, Denis, Englund, Johanna, Narhi, Katja, Haglund, Caj, Kovanen, Panu E., Verschuren, Emmy W., Klefstrom, Juha

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Faulty Epithelial Polarity Genes and Cancer von Tervonen, Topi A., Partanen, Johanna I., Saarikoski, Sirkku T., Myllynen, Mikko, Marques, Elsa, Paasonen, Katriina, Moilanen, Anu, Wohlfahrt, Gerd, Kovanen, Panu E., Klefstrom, Juha

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Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization Platform von Pant, Shishir M, Mukonoweshuro, Amanda, Desai, Bimbisar, Ramjee, Manoj K, Selway, Christopher N, Tarver, Gary J, Wright, Adrian G, Birchall, Kristian, Chapman, Timothy M, Tervonen, Topi A, Klefström, Juha

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Analyzing the Type II Transmembrane Serine Protease Hepsin-Dependent Basement Membrane Remodeling in 3D Cell Culture von Pant, Shishir M., Belitskin, Denis, Ala-Hongisto, Hanna, Klefström, Juha, Tervonen, Topi A.

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Overexpression of a truncated TrkB isoform increases the proliferation of neural progenitors von Tervonen, Topi A., Ajamian, Farzam, De Wit, Joris, Verhaagen, Joost, Castrén, Eero, Castrén, Maija

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Abstract 5817: LKB1 overcomes RAS pathway-mediated loss of epithelial integrity von Tervonen, Topi A., Pant, Shishir M., Englund, Johanna, Klefström, Juha

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Abstract 3484: Ras recruits oncogenic serine protease hepsin to disrupt mammary epithelial integrity von Tervonen, Topi A., Pant, Shishir M., Belitskin, Denis, Englund, Johanna, Närhi, Katja, Verschuren, Emmy, Kovanen, Panu, Klefström, Juha

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Breaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4 von Partanen, Johanna I., Tervonen, Topi A., Klefström, Juha

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Abstract 834: Serine protease hepsin regulates tumor growth via TGFbeta-EGFR signaling axis von Tervonen, Topi A., Belitškin, Denis, Munne, Pauliina, Pant, Shishir M., Suleymanova, Ilida, Belitškina, Kati, Pouwels, Jeroen, Klefström, Juha

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Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis von Nieminen, Anni I., Eskelinen, Vilja M., Haikala, Heidi M., Tervonen, Topi A., Yan, Yan, Partanen, Johanna I., Klefström, Juha

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Overexpression of a truncated TrkB isoform increases the proliferation of neural progenitors von Tervonen, Topi A, Ajamian, Farzam, de Wit, Joris, Verhaagen, Joost, Castren, Eero, Castren, Maija

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Real-time monitoring of human blood-brain barrier disruption von Kiviniemi, Vesa, Korhonen, Vesa, Kortelainen, Jukka, Rytky, Seppo, Keinänen, Tuija, Tuovinen, Timo, Isokangas, Matti, Sonkajärvi, Eila, Siniluoto, Topi, Nikkinen, Juha, Alahuhta, Seppo, Tervonen, Osmo, Turpeenniemi-Hujanen, Taina, Myllylä, Teemu, Kuittinen, Outi, Voipio, Juha

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Abstract LB-204: Oncogenic Ras signaling requires serine protease hepsin to induce invasive breast cancer phenotype von Pant, Shishir Mani, Tervonen, Topi, Belitskin, Denis, Englund, Johanna, Verschuren, Emmy, Kovanen, Panu, Klefstrom, Juha

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