A RhoA-YAP-c-Myc signaling axis promotes the development of polycystic kidney disease von Cai, Jing, Song, Xuewen, Wang, Wei, Watnick, Terry, Pei, York, Qian, Feng, Pan, Duojia

Volltext

Primary results of the randomized trial of metformin administration in polycystic kidney disease (TAME PKD) von Perrone, Ronald D., Abebe, Kaleab Z., Watnick, Terry J., Althouse, Andrew D., Hallows, Kenneth R., Lalama, Christina M., Miskulin, Dana C., Seliger, Stephen L., Tao, Cheng, Harris, Peter C., Bae, Kyongtae Ty

Volltext

Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis von Muto, Yoshiharu, Dixon, Eryn E., Yoshimura, Yasuhiro, Wu, Haojia, Omachi, Kohei, Ledru, Nicolas, Wilson, Parker C., King, Andrew J., Eric Olson, N., Gunawan, Marvin G., Kuo, Jay J., Cox, Jennifer H., Miner, Jeffrey H., Seliger, Stephen L., Woodward, Owen M., Welling, Paul A., Watnick, Terry J., Humphreys, Benjamin D.

Volltext

Mutations in GANAB, Encoding the Glucosidase IIα Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver Disease von Porath, Binu, Gainullin, Vladimir G., Cornec-Le Gall, Emilie, Dillinger, Elizabeth K., Heyer, Christina M., Hopp, Katharina, Edwards, Marie E., Madsen, Charles D., Mauritz, Sarah R., Banks, Carly J., Baheti, Saurabh, Reddy, Bharathi, Herrero, José Ignacio, Bañales, Jesús M., Hogan, Marie C., Tasic, Velibor, Watnick, Terry J., Chapman, Arlene B., Vigneau, Cécile, Lavainne, Frédéric, Audrézet, Marie-Pierre, Ferec, Claude, Le Meur, Yannick, Torres, Vicente E., Harris, Peter C.

Volltext

Mutations in GANAB, Encoding the Glucosidase IIa Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver Disease von Porath, Binu, Gainullin, Vladimir G, Gall, Emilie Cornec-Le, Dillinger, Elizabeth K, Heyer, Christina M, Hopp, Katharina, Edwards, Marie E, Madsen, Charles D, Mauritz, Sarah R, Banks, Carly J, Baheti, Saurabh, Reddy, Bharathi, Herrero, José Ignacio, Bañales, Jesús M, Hogan, Marie C, Tasic, Velibor, Watnick, Terry J, Chapman, Arlene B, Vigneau, Cécile, Lavainne, Frédéric, Audrézet, Marie-Pierre, Ferec, Claude, Meur, Yannick Le, Torres, Vicente E, Group, Genkyst Study, Harris, Peter C

Volltext

Polycystin‐1 dependent regulation of polycystin‐2 via GRP94, a member of HSP90 family that resides in the endoplasmic reticulum von Yao, Qin, Outeda, Patricia, Xu, Hangxue, Walker, Rebecca, Basquin, Denis, Qian, Feng, Cebotaru, Liudmila, Watnick, Terry, Cebotaru, Valeriu

Volltext

Isolated polycystic liver disease genes define effectors of polycystin-1 function von Besse, Whitney, Dong, Ke, Choi, Jungmin, Punia, Sohan, Fedeles, Sorin V, Choi, Murim, Gallagher, Anna-Rachel, Huang, Emily B, Gulati, Ashima, Knight, James, Mane, Shrikant, Tahvanainen, Esa, Tahvanainen, Pia, Sanna-Cherchi, Simone, Lifton, Richard P, Watnick, Terry, Pei, York P, Torres, Vicente E, Somlo, Stefan

Volltext

Monoallelic IFT140 pathogenic variants are an important cause of the autosomal dominant polycystic kidney-spectrum phenotype von Senum, Sarah R., Li, Ying (Sabrina) M., Benson, Katherine A., Joli, Giancarlo, Olinger, Eric, Lavu, Sravanthi, Madsen, Charles D., Gregory, Adriana V., Neatu, Ruxandra, Kline, Timothy L., Audrézet, Marie-Pierre, Outeda, Patricia, Nau, Cherie B., Meijer, Esther, Ali, Hamad, Steinman, Theodore I., Mrug, Michal, Phelan, Paul J., Watnick, Terry J., Peters, Dorien J.M., Ong, Albert C.M., Conlon, Peter J., Perrone, Ronald D., Cornec-Le Gall, Emilie, Hogan, Marie C., Torres, Vicente E., Sayer, John A., Harris, Peter C.

Volltext

Characterizing the impact of the Covid-19 pandemic on adults with autosomal dominant polycystic kidney disease: a cross-sectional study von Shetty, Alok, Atalla, Anthony, Diggs, Charalett, Watnick, Terry, Seliger, Stephen

Volltext

Tolvaptan in Autosomal Dominant Polycystic Kidney Disease: Three Years' Experience von Higashihara, Eiji, Torres, Vicente E, Chapman, Arlene B, Grantham, Jared J, Bae, Kyongtae, Watnick, Terry J, Horie, Shigeo, Nutahara, Kikuo, Ouyang, John, Krasa, Holly B, Czerwiec, Frank S

Volltext

Multiomics profiling of mouse polycystic kidney disease progression at a single-cell resolution von Muto, Yoshiharu, Yoshimura, Yasuhiro, Wu, Haojia, Chang-Panesso, Monica, Ledru, Nicolas, Woodward, Owen M, Outeda, Patricia, Cheng, Tao, Mahjoub, Moe R, Watnick, Terry J, Humphreys, Benjamin D

Volltext

Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism von Kim, Hyunho, Xu, Hangxue, Yao, Qin, Li, Weizhe, Huang, Qiong, Outeda, Patricia, Cebotaru, Valeriu, Chiaravalli, Marco, Boletta, Alessandra, Piontek, Klaus, Germino, Gregory G., Weinman, Edward J., Watnick, Terry, Qian, Feng

Volltext

Inhibition of histone deacetylase 6 activity reduces cyst growth in polycystic kidney disease von Cebotaru, Liudmila, Liu, Qiangni, Yanda, Murali K., Boinot, Clement, Outeda, Patricia, Huso, David L., Watnick, Terry, Guggino, William B., Cebotaru, Valeriu

Volltext

mTOR Inhibitors in Polycystic Kidney Disease von Watnick, Terry, Germino, Gregory G

Volltext

Fibrocystin/Polyductin releases a C-terminal fragment that translocates into mitochondria and suppresses cystogenesis von Walker, Rebecca V, Yao, Qin, Xu, Hangxue, Maranto, Anthony, Swaney, Kristen F, Ramachandran, Sreekumar, Li, Rong, Cassina, Laura, Polster, Brian M, Outeda, Patricia, Boletta, Alessandra, Watnick, Terry, Qian, Feng

Volltext

Establishing a Core Outcome Set for Autosomal Dominant Polycystic Kidney Disease: Report of the Standardized Outcomes in Nephrology–Polycystic Kidney Disease (SONG-PKD) Consensus W... von Tong, Allison, Craig, Jonathan C., Mustafa, Reem A., Perrone, Ronald D., Ahn, Curie, Fowler, Kevin, Gansevoort, Ron T., Ong, Albert C.M., Coolican, Helen, Harris, Tess, Gutman, Talia, Shen, Jenny I., Viecelli, Andrea K., Johnson, David W., Au, Eric, El-Damanawi, Ragada, Logeman, Charlotte, Ju, Angela, Manera, Karine E., Chonchol, Michel, Pei, York, Sautenet, Benedicte, Rastogi, Anjay, Sharma, Ankit, Yu, Alan, Thompson, Aliza, Viecelli, Andrea, Mallett, Andrew, Ju, Angela, Wang, Angela, Sharma, Ankit, Nadeau-Fredette, Annie-Claire, Chapman, Arlene, Teixeira-Pinto, Armando, Canaud, Bernard, Manns, Braden, Hawley, Carmel, Logeman, Charlotte, Chao, Chia-Ter, Ahn, Curie, Sumpton, Daniel, Harris, David, Johnson, David, Wheeler, David, Mekahli, Djalila, O’Donoghue, Donal, Peters, Dorien, O'Lone, Emma, Czerwiec, Frank, Oskoui, Frederic Rahbari, Rangan, Gopi, Park, Hayne, Ryu, Hyunjin, Gill, John, Kao, Juliana, Eckardt, Kai-Uwe, Manera, Karine, Van, Kim Linh, Krishnan, Mahesh, Hogan, Marie, Howell, Martin, Park, Meyeon, Mrug, Michal, Chonchol, Michel, Ta, Michelle, Harris, Peter, Garimella, Pranav, Krishnasamy, Rathika, Mustafa, Reem, McGee, Richard, Pecoits-Filho, Roberto, Gansevoort, Ron, Perrone, Ronald, Chan, Samuel, Bernays, Sarah, Horie, Shigeo, Palmer, Suetonia, Mendley, Susan, Gutman, Talia, Watnick, Terry, Hiemstra, Thomas, Weimbs, Thomas, Torres, Vicente, Jha, Vivek, Winkelmayer, Wolfgang, Cho, Yeoungjee, Pei, York, Baron, David, Clark, David, McGinty-Poteet, Debra, Odland, Dwight, King, Elizabeth, Vickers, Frances, Coolican, Helen, Odland, Jean, Lee, Lynore, Vickers, Marvin, Johnston-Clark, Mary, Harris, Tess, Baron, Zachary

Volltext

TRPP2 and TRPV4 form a polymodal sensory channel complex von Köttgen, Michael, Buchholz, Björn, Garcia-Gonzalez, Miguel A, Kotsis, Fruzsina, Fu, Xiao, Doerken, Mara, Boehlke, Christopher, Steffl, Daniel, Tauber, Robert, Wegierski, Tomasz, Nitschke, Roland, Suzuki, Makoto, Kramer-Zucker, Albrecht, Germino, Gregory G, Watnick, Terry, Prenen, Jean, Nilius, Bernd, Kuehn, E. Wolfgang, Walz, Gerd

Volltext

GDNF drives rapid tubule morphogenesis in a novel 3D in vitro model for ADPKD von Dixon, Eryn E, Maxim, Demetrios S, Halperin Kuhns, Victoria L, Lane-Harris, Allison C, Outeda, Patricia, Ewald, Andrew J, Watnick, Terry J, Welling, Paul A, Woodward, Owen M

Volltext

A Randomized Clinical Trial of Metformin to Treat Autosomal Dominant Polycystic Kidney Disease von Seliger, Stephen L., Abebe, Kaleab Z., Hallows, Kenneth R., Miskulin, Dana C., Perrone, Ronald D., Watnick, Terry, Bae, Kyongtae Tae

Volltext

Dual mTOR/PI3K inhibition limits PI3K-dependent pathways activated upon mTOR inhibition in autosomal dominant polycystic kidney disease von Liu, Yang, Pejchinovski, Martin, Wang, Xueqi, Fu, Xuebin, Castelletti, Deborah, Watnick, Terry J., Arcaro, Alexandre, Siwy, Justyna, Mullen, William, Mischak, Harald, Serra, Andreas L.

Volltext