Solvent Deuterium Oxide Isotope Effects on the Reactions of Organophosphorylated Acetylcholinesterase von Rosenberry, Terrone L

Volltext

Probing the Peripheral Site of Human Butyrylcholinesterase von Macdonald, Ian R, Martin, Earl, Rosenberry, Terrone L, Darvesh, Sultan

Volltext

A Second Look at the Crystal Structures of Drosophila melanogaster Acetylcholinesterase in Complex with Tacrine Derivatives Provides Insights Concerning Catalytic Intermediates and... von Nachon, Florian, Rosenberry, Terrone L, Silman, Israel, Sussman, Joel L

Volltext

Rate-limiting step in the decarbamoylation of acetylcholinesterases with large carbamoyl groups von Rosenberry, Terrone L., Cheung, Jonah

Volltext

Decarbamoylation of acetylcholinesterases is markedly slowed as carbamoyl groups increase in size von Venkatasubban, Kunisi S., Johnson, Joseph L., Thomas, Jamie L., Fauq, Abdul, Cusack, Bernadette, Rosenberry, Terrone L.

Volltext

Oligomer Formation by Amyloid-β42 in a Membrane-Mimicking Environment in Alzheimer's Disease von Rosenberry, Terrone L, Zhou, Huan-Xiang, Stagg, Scott M, Paravastu, Anant K

Volltext

Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study von Rosenberry, Terrone L, Brazzolotto, Xavier, Macdonald, Ian R, Wandhammer, Marielle, Trovaslet-Leroy, Marie, Darvesh, Sultan, Nachon, Florian

Volltext

The Natural Product Dihydrotanshinone I Provides a Prototype for Uncharged Inhibitors That Bind Specifically to the Acetylcholinesterase Peripheral Site with Nanomolar Affinity von Beri, Veena, Wildman, Scott A, Shiomi, Kazuro, Al-Rashid, Ziyad F, Cheung, Jonah, Rosenberry, Terrone L

Volltext

Strategies to Resolve the Catalytic Mechanism of Acetylcholinesterase von Rosenberry, Terrone L.

Volltext

Development of acetophenone ligands as potential neuroimaging agents for cholinesterases von Jollymore-Hughes, Courtney T., Pottie, Ian R., Martin, Earl, Rosenberry, Terrone L., Darvesh, Sultan

Volltext

Structures of Human Acetylcholinesterase Bound to Dihydrotanshinone I and Territrem B Show Peripheral Site Flexibility von Cheung, Jonah, Gary, Ebony N, Shiomi, Kazuro, Rosenberry, Terrone L

Volltext

Acetylcholinesterase Complexes with the Natural Product Inhibitors Dihydrotanshinone I and Territrem B: Binding Site Assignment from Inhibitor Competition and Validation Through Cr... von Cheung, Jonah, Beri, Veena, Shiomi, Kazuro, Rosenberry, Terrone L.

Volltext

Analysis of the Reaction of Carbachol with Acetylcholinesterase Using Thioflavin T As a Coupled Fluorescence Reporter von Rosenberry, Terrone L., Sonoda, Leilani K., Dekat, Sarah E., Cusack, Bernadette, Johnson, Joseph L.

Volltext

Drug-like Leads for Steric Discrimination between Substrate and Inhibitors of Human Acetylcholinesterase von Wildman, Scott A., Zheng, Xiange, Sept, David, Auletta, Jeffrey T., Rosenberry, Terrone L., Marshall, Garland R.

Volltext

Molecular basis of inhibition of substrate hydrolysis by a ligand bound to the peripheral site of acetylcholinesterase von Auletta, Jeffrey T., Johnson, Joseph L., Rosenberry, Terrone L.

Volltext

Hopeahainol A binds reversibly at the acetylcholinesterase (AChE) peripheral site and inhibits enzyme activity with a novel higher order concentration dependence von Rosenberry, Terrone L., Martin, Patricia K., Nix, A. Jeremy, Wildman, Scott A., Cheung, Jonah, Snyder, Scott A., Tan, Ren Xiang

Volltext

Biophysical Analyses of Synthetic Amyloid-β(1−42) Aggregates before and after Covalent Cross-Linking. Implications for Deducing the Structure of Endogenous Amyloid-β Oligomers von Moore, Brenda D, Rangachari, Vijayaraghavan, Tay, William M, Milkovic, Nicole M, Rosenberry, Terrone L

Volltext

Accumulation of Pathological Tau Species and Memory Loss in a Conditional Model of Tauopathy von Berger, Zdenek, Roder, Hanno, Hanna, Amanda, Carlson, Aaron, Rangachari, Vijayaraghavan, Yue, Mei, Wszolek, Zbigniew, Ashe, Karen, Knight, Joshua, Dickson, Dennis, Andorfer, Cathy, Rosenberry, Terrone L, Lewis, Jada, Hutton, Mike, Janus, Christopher

Volltext

Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation von Zheng, Honghua, Liu, Chia-Chen, Atagi, Yuka, Chen, Xiao-Fen, Jia, Lin, Yang, Longyu, He, Wencan, Zhang, Xilin, Kang, Silvia S., Rosenberry, Terrone L., Fryer, John D., Zhang, Yun-Wu, Xu, Huaxi, Bu, Guojun

Volltext

Cathepsin D regulates cerebral Aβ42/40 ratios via differential degradation of Aβ42 and Aβ40 von Suire, Caitlin N., Abdul-Hay, Samer O., Sahara, Tomoko, Kang, Dongcheul, Brizuela, Monica K., Saftig, Paul, Dickson, Dennis W., Rosenberry, Terrone L., Leissring, Malcolm A.

Volltext