Overcoming the blood–brain tumor barrier for effective glioblastoma treatment von van Tellingen, O, Yetkin-Arik, B, de Gooijer, M.C, Wesseling, P, Wurdinger, T, de Vries, H.E

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Cognitive impact of cytotoxic agents in mice von Seigers, R., Loos, M., Van Tellingen, O., Boogerd, W., Smit, A. B., Schagen, S. B.

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Chemotherapy-related cognitive dysfunction: current animal studies and future directions von Seigers, R., Schagen, S. B., Van Tellingen, O., Dietrich, J.

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Cremophor EL causes (pseudo-) non-linear pharmacokinetics of paclitaxel in patients von VAN TELLINGEN, O, HUIZING, M. T, PANDAY, V. R. N, SCHELLENS, J. H. M, NOOIJEN, W. J, BEIJNEN, J. H

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Therapy-resistant tumor microvascular endothelial cells contribute to treatment failure in glioblastoma multiforme von Borovski, T, Beke, P, van Tellingen, O, Rodermond, H M, Verhoeff, J J, Lascano, V, Daalhuisen, J B, Medema, J P, Sprick, M R

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Neurobiological changes by cytotoxic agents in mice von Seigers, R., Loos, M., Van Tellingen, O., Boogerd, W., Smit, A.B., Schagen, S.B.

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A validated HPLC-MS/MS method for simultaneously analyzing curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetra-hydrocurcumin and piperine in human plasma, urine or feces von Kroon, M.A.G.M., van Laarhoven, H.W.M., Swart, E.L., Kemper, E.M., van Tellingen, O.

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Fractionated brain X-irradiation profoundly reduces hippocampal immature neuron numbers without affecting spontaneous behavior in mice von Kuil, L.E., Seigers, R., Loos, M., de Gooijer, M.C., Compter, A., Boogerd, W., van Tellingen, O., Smit, A.B., Schagen, S.B.

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Strategies to target drugs to gliomas and CNS metastases of solid tumors von Milojkovic Kerklaan, B., van Tellingen, O., Huitema, A. D. R., Beijnen, J. H., Boogerd, W., Schellens, J. H. M., Brandsma, D.

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Characterisation of tumour vasculature in mouse brain by USPIO contrast-enhanced MRI von Gambarota, G, Leenders, W, Maass, C, Wesseling, P, van der Kogel, B, van Tellingen, O, Heerschap, A

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From Mouse to Man: Predictions of Human Pharmacokinetics of Orally Administered Docetaxel From Preclinical Studies von Koolen, S. L. W., van Waterschoot, R. A. B., van Tellingen, O., Schinkel, A. H., Beijnen, J. H., Schellens, J. H. M., Huitema, A. D. R.

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16 Quadruple vertical targeting of an oncogenic pathway as a treatment strategy to prevent drug resistance von Neto, J, Van Tellingen, O, Villanueva, A, Bernards, R

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Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdr1a P-glycoprotein von Asperen, J van, Tellingen, O van, Tijssen, F, Schinkel, A H, Beijnen, J H

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Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs von Schinkel, A.H., Smit, J.J.M., van Tellingen, O., Beijnen, J.H., Wagenaar, E., van Deemter, L., Mol, C.A.A.M., van der Valk, M.A., Robanus-Maandag, E.C., te Riele, H.P.J., Berns, A.J.M., Borst, P.

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Improved penetration of docetaxel into the brain by co-administration of inhibitors of P-glycoprotein von Kemper, E.M., Verheij, M., Boogerd, W., Beijnen, J.H., van Tellingen, O.

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Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studies von Kemper, E.M., Leenders, W., Küsters, B., Lyons, S., Buckle, T., Heerschap, A., Boogerd, W., Beijnen, J.H., van Tellingen, O.

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Paclitaxel in self-micro emulsifying formulations: oral bioavailability study in mice von Oostendorp, Roos L., Buckle, T., Lambert, G., Garrigue, J. S., Beijnen, J. H., Schellens, J. H. M., van Tellingen, O.

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Disposition and toxicity of trabectedin (ET-743) in wild-type and mdr1 gene (P-gp) knock-out mice von Beumer, J. H., Franke, N. E., Tolboom, R., Buckle, T., Rosing, H., Lopez-Lazaro, L., Schellens, J. H. M., Beijnen, J. H., van Tellingen, O.

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PD-0239 PRE-CLINICAL IMPLEMENTATION OF A SMALL ANIMAL IMAGE-GUIDED IRRADIATOR von Gasparini, A, de Gooijer, M.C, te Poele, H, Stewart, F, van Tellingen, O, Sonke, J.J

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The ABCB1/ABCG2 inhibitor elacridar is a more potent pharmacoenhancer compared to tariquidar for treatment of intracranial tumors with small molecule drugs von Van Tellingen, O., Lentzas, A., Zuidema, S., Çitirikkaya, C., Venekamp, N., Beijnen, J.

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