A Novel Triazolopyridine-Based Spleen Tyrosine Kinase Inhibitor That Arrests Joint Inflammation von Ferguson, Gregory D, Delgado, Mercedes, Plantevin-Krenitsky, Veronique, Jensen-Pergakes, Kristen, Bates, R J, Torres, Sanaa, Celeridad, Maria, Brown, Heather, Burnett, Kelven, Nadolny, Lisa, Tehrani, Lida, Packard, Garrick, Pagarigan, Barbra, Haelewyn, Jason, Nguyen, Trish, Xu, Li, Tang, Yang, Hickman, Matthew, Baculi, Frans, Pierce, Steven, Miyazawa, Keiji, Jackson, Pilgrim, Chamberlain, Philip, LeBrun, Laurie, Xie, Weilin, Bennett, Brydon, Blease, Kate

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[ 3H]-Methoxymethyl-MTEP and [ 3H]-Methoxy-PEPy: potent and selective radioligands for the metabotropic glutamate subtype 5 (mGlu5) receptor von Cosford, Nicholas D.P, Roppe, Jeffrey, Tehrani, Lida, Schweiger, Edwin J, Seiders, T.Jon, Chaudary, Ashok, Rao, Sara, Varney, Mark A

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Discovery and optimization of thieno[2,3-d]pyrimidines as B-Raf inhibitors von Packard, Garrick K., Papa, Patrick, Riggs, Jennifer R., Erdman, Paul, Tehrani, Lida, Robinson, Dale, Harris, Roy, Shevlin, Graziella, Perrin-Ninkovic, Sophie, Hilgraf, Robert, McCarrick, Margaret A., Tran, Tam, Fleming, Yuedi, Bai, April, Richardson, Samantha, Katz, Jason, Tang, Yang, Leisten, Jim, Moghaddam, Mehran, Cathers, Brian, Zhu, Dan, Sakata, Steven

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Design and Synthesis of Novel Cereblon Binders for Use in Targeted Protein Degradation von Norris, Stephen, Ba, Xiaochu, Rhodes, Jayce, Huang, Dehua, Khambatta, Gody, Buenviaje, Jennifer, Nayak, Surendra, Meiring, Joseph, Reiss, Samantha, Xu, Shuichan, Shi, Lihong, Whitefield, Brandon, Alexander, Matt, Horn, Evan J., Correa, Matthew, Tehrani, Lida, Hansen, Joshua D., Papa, Patrick, Mortensen, Deborah S.

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Correction to “Design and Synthesis of Novel Cereblon Binders for Use in Targeted Protein Degradation” von Norris, Stephen, Ba, Xiaochu, Rhodes, Jayce, Huang, Dehua, Khambatta, Gody, Buenviaje, Jennifer, Nayak, Surendra, Meiring, Joseph, Reiss, Samantha, Xu, Shuichan, Shi, Lihong, Whitefield, Brandon, Alexander, Matt, Horn, Evan J., Correa, Matthew, Tehrani, Lida, Hansen, Joshua D., Papa, Patrick, Mortensen, Deborah S., Brazeau, Jean-François

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The Discovery of a Dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) Inhibitor for the Treatment of Triple Negative Breast Cancer Initiated from a Phenotypic Screen von Riggs, Jennifer R, Nagy, Mark, Elsner, Jan, Erdman, Paul, Cashion, Dan, Robinson, Dale, Harris, Roy, Huang, Dehua, Tehrani, Lida, Deyanat-Yazdi, Gordafaried, Narla, Rama Krishna, Peng, Xiaohui, Tran, Tam, Barnes, Leo, Miller, Terra, Katz, Jason, Tang, Yang, Chen, Ming, Moghaddam, Mehran F, Bahmanyar, Sogole, Pagarigan, Barbra, Delker, Silvia, LeBrun, Laurie, Chamberlain, Philip P, Calabrese, Andrew, Canan, Stacie S, Leftheris, Katerina, Zhu, Dan, Boylan, John F

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Structure-Guided Optimization Provides a Series of TTK Protein Inhibitors with Potent Antitumor Activity von Elsner, Jan, Cashion, Dan, Robinson, Dale, Bahmanyar, Sogole, Tehrani, Lida, Fultz, Kimberly E, Narla, Rama Krishna, Peng, Xiaohui, Tran, Tam, Apuy, Julius, LeBrun, Laurie, Leftheris, Katerina, Boylan, John F, Zhu, Dan, Riggs, Jennifer R

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3-[Substituted]-5-(5-pyridin-2-yl-2 H-tetrazol-2-yl)benzonitriles: Identification of highly potent and selective metabotropic glutamate subtype 5 receptor antagonists von Tehrani, Lida R., Smith, Nicholas D., Huang, Dehua, Poon, Steve F., Roppe, Jeffrey R., Seiders, Thomas Jon, Chapman, Deborah F., Chung, Janice, Cramer, Merryl, Cosford, Nicholas D.P.

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Design and Optimization Leading to an Orally Active TTK Protein Kinase Inhibitor with Robust Single Agent Efficacy von Riggs, Jennifer R, Elsner, Jan, Cashion, Dan, Robinson, Dale, Tehrani, Lida, Nagy, Mark, Fultz, Kimberly E, Krishna Narla, Rama, Peng, Xiaohui, Tran, Tam, Kulkarni, Ashutosh, Bahmanyar, Sogole, Condroski, Kevin, Pagarigan, Barbra, Fenalti, Gustavo, LeBrun, Laurie, Leftheris, Katerina, Zhu, Dan, Boylan, John F

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3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]- pyridine:  A Potent and Highly Selective Metabotropic Glutamate Subtype 5 Receptor Antagonist with Anxiolytic Activity von Cosford, Nicholas D. P, Tehrani, Lida, Roppe, Jeffrey, Schweiger, Edwin, Smith, Nicholas D, Anderson, Jeffrey, Bristow, Linda, Brodkin, Jesse, Jiang, Xiaohui, McDonald, Ian, Rao, Sara, Washburn, Mark, Varney, Mark A

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Discovery of Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor CC-223 von Mortensen, Deborah S, Perrin-Ninkovic, Sophie M, Shevlin, Graziella, Zhao, Jingjing, Packard, Garrick, Bahmanyar, Sogole, Correa, Matthew, Elsner, Jan, Harris, Roy, Lee, Branden G. S, Papa, Patrick, Parnes, Jason S, Riggs, Jennifer R, Sapienza, John, Tehrani, Lida, Whitefield, Brandon, Apuy, Julius, Bisonette, René R, Gamez, James C, Hickman, Matt, Khambatta, Godrej, Leisten, Jim, Peng, Sophie X, Richardson, Samantha J, Cathers, Brian E, Canan, Stacie S, Moghaddam, Mehran F, Raymon, Heather K, Worland, Peter, Narla, Rama Krishna, Fultz, Kimberly E, Sankar, Sabita

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The Behavioral Profile of the Potent and Selective mGlu5 Receptor Antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) in Rodent Models of Anxiety von BUSSE, Chris S, BRODKIN, Jesse, TATTERSALL, David, ANDERSON, Jeffery J, WARREN, Noelle, TEHRANI, Lida, BRISTOW, Linda J, VARNEY, Mark A, COSFORD, Nicholas D. P

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Substituted Xanthines, Pteridinediones, and Related Compounds as Potential Antiinflammatory Agents. Synthesis and Biological Evaluation of Inhibitors of Tumor Necrosis Factor α von Cottam, Howard B, Shih, Hsiencheng, Tehrani, Lida R, Wasson, D. Bruce, Carson, Dennis A

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Comparison of Self-efficacy, Test Anxiety and Competitiveness between Students of Top Private Schools and Public Schools von Tehrani, Lida Assadi, Majd, Mojtaba Amiri, Ghamari, Mohammad

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Discovery of Novel Heteroarylazoles That Are Metabotropic Glutamate Subtype 5 Receptor Antagonists with Anxiolytic Activity von Roppe, Jeffrey, Smith, Nicholas D, Huang, Dehua, Tehrani, Lida, Wang, Bowei, Anderson, Jeffrey, Brodkin, Jesse, Chung, Janice, Jiang, Xiaohui, King, Christopher, Munoz, Benito, Varney, Mark A, Prasit, Petpiboon, Cosford, Nicholas D. P

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The design and synthesis of potent and cell-active allosteric dual Akt 1 and 2 inhibitors devoid of hERG activity von Siu, Tony, Li, Yiwei, Nagasawa, Johnny, Liang, Jun, Tehrani, Lida, Chua, Peter, Jones, Raymond E., Defeo-Jones, Deborah, Barnett, Stanley F., Robinson, Ronald G.

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5-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-2,3′-bipyridine: a highly potent, orally active metabotropic glutamate subtype 5 (mGlu5) receptor antagonist with anxiolytic activity von Roppe, Jeffrey R, Wang, Bowei, Huang, Dehua, Tehrani, Lida, Kamenecka, Theodore, Schweiger, Edwin J, Anderson, Jeffery J, Brodkin, Jesse, Jiang, Xiaohui, Cramer, Merryl, Chung, Janice, Reyes-Manalo, Grace, Munoz, Benito, Cosford, Nicholas D.P

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2-{2-[3-(Pyridin-3-yloxy)phenyl]-2 H-tetrazol-5-yl}pyridine: a highly potent, orally active, metabotropic glutamate subtype 5 (mGlu5) receptor antagonist von Huang, Dehua, Poon, Steve F., Chapman, Deborah F., Chung, Janice, Cramer, Merryl, Reger, Thomas S., Roppe, Jeffrey R., Tehrani, Lida, Cosford, Nicholas D.P., Smith, Nicholas D.

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Discovery of highly potent, selective, orally bioavailable, metabotropic glutamate subtype 5 (mGlu5) receptor antagonists devoid of cytochrome P450 1A2 inhibitory activity von Smith, Nicholas D., Poon, Steve F., Huang, Dehua, Green, Mitchell, King, Christopher, Tehrani, Lida, Roppe, Jeffrey R., Chung, Janice, Chapman, Deborah P., Cramer, Merryl, Cosford, Nicholas D.P.

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Cyclohexenyl- and dehydropiperidinyl-alkynyl pyridines as potent metabotropic glutamate subtype 5 (mGlu5) receptor antagonists von Chua, Peter C., Nagasawa, Johnny Y., Bleicher, Leo S., Munoz, Benito, Schweiger, Edwin J., Tehrani, Lida, Anderson, Jeffrey J., Cramer, Merryl, Chung, Janice, Green, Mitchell D., King, Chris D., Reyes-Manalo, Grace, Cosford, Nicholas D.P.

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