β-lactam/β-lactamase inhibitor combinations: an update von Tehrani, Kamaleddin H. M. E, Martin, Nathaniel I

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Novel Carbapenemases FLC-1 and IMI-2 Encoded by an Enterobacter cloacae Complex Isolated from Food Products von Brouwer, Michael S M, Tehrani, Kamaleddin H M E, Rapallini, Michel, Geurts, Yvon, Kant, Arie, Harders, Frank, Mashayekhi, Vida, Martin, Nathaniel I, Bossers, Alex, Mevius, Dik J, Wit, Ben, Veldman, Kees T

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Darobactins Exhibiting Superior Antibiotic Activity by Cryo‐EM Structure Guided Biosynthetic Engineering von Seyfert, Carsten E., Porten, Christoph, Yuan, Biao, Deckarm, Selina, Panter, Fabian, Bader, Chantal D., Coetzee, Janetta, Deschner, Felix, Tehrani, Kamaleddin H. M. E., Higgins, Paul G., Seifert, Harald, Marlovits, Thomas C., Herrmann, Jennifer, Müller, Rolf

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Cephalosporin Prodrug Inhibitors Overcome Metallo‐β‐Lactamase Driven Antibiotic Resistance von Haren, Matthijs J., Tehrani, Kamaleddin H. M. E., Kotsogianni, Ioli, Wade, Nicola, Brüchle, Nora C., Mashayekhi, Vida, Martin, Nathaniel I.

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Novel Cephalosporin Conjugates Display Potent and Selective Inhibition of Imipenemase-Type Metallo-β-Lactamases von Tehrani, Kamaleddin H. M. E, Wade, Nicola, Mashayekhi, Vida, Brüchle, Nora C, Jespers, Willem, Voskuil, Koen, Pesce, Diego, van Haren, Matthijs J, van Westen, Gerard J. P, Martin, Nathaniel I

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Crystal structure of natural product argyrin-D determined by 3D electron diffraction von Gorelik, Tatiana E, Tehrani, Kamaleddin H. M. E, Gruene, Tim, Monecke, Thomas, Niessing, Dierk, Kaiser, Ute, Blankenfeldt, Wulf, Mller, Rolf

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Aminocarboxylic acids related to aspergillomarasmine A (AMA) and ethylenediamine-N,N′-disuccinic acid (EDDS) are strong zinc-binders and inhibitors of the metallo-beta-lactamase ND... von Tehrani, Kamaleddin H. M. E., Fu, Haigen, Bruchle, Nora C., Mashayekhi, Vida, Lujan, Alejandro Prats, van Haren, Matthijs J., Poetarends, Gerrit J., Martin, Nathaniel

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Mechanistic Investigations of Metallo‐β‐lactamase Inhibitors: Strong Zinc Binding Is Not Required for Potent Enzyme Inhibition von Wade, Nicola, Tehrani, Kamaleddin H. M. E., Brüchle, Nora C., Haren, Matthijs J., Mashayekhi, Vida, Martin, Nathaniel I.

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Probing the Interaction of Aspergillomarasmine A with Metallo-β-lactamases NDM-1, VIM-2, and IMP‑7 von Bergstrom, Alexander, Katko, Andrew, Adkins, Zach, Hill, Jessica, Cheng, Zishuo, Burnett, Mia, Yang, Hao, Aitha, Mahesh, Mehaffey, M. Rachel, Brodbelt, Jennifer S, Tehrani, Kamaleddin H. M. E, Martin, Nathaniel I, Bonomo, Robert A, Page, Richard C, Tierney, David L, Fast, Walter, Wright, Gerard D, Crowder, Michael W

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Host defence peptide plectasin targets bacterial cell wall precursor lipid II by a calcium-sensitive supramolecular mechanism von Jekhmane, Shehrazade, Derks, Maik G. N., Maity, Sourav, Slingerland, Cornelis J., Tehrani, Kamaleddin H. M. E., Medeiros-Silva, João, Charitou, Vicky, Ammerlaan, Danique, Fetz, Céline, Consoli, Naomi A., Cochrane, Rachel V. K., Matheson, Eilidh J., van der Weijde, Mick, Elenbaas, Barend O. W., Lavore, Francesca, Cox, Ruud, Lorent, Joseph H., Baldus, Marc, Künzler, Markus, Lelli, Moreno, Cochrane, Stephen A., Martin, Nathaniel I., Roos, Wouter H., Breukink, Eefjan, Weingarth, Markus

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Aspergillomarasmine A inhibits metallo-β-lactamases by selectively sequestering Zn2 von Sychantha, David, Rotondo, Caitlyn M., Tehrani, Kamaleddin H.M.E., Martin, Nathaniel I., Wright, Gerard D.

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A New Tool to Reveal Bacterial Signaling Mechanisms in Antibiotic Treatment and Resistance von Lin, Miao-Hsia, Potel, Clement M., Tehrani, Kamaleddin H.M.E., Heck, Albert J.R., Martin, Nathaniel I., Lemeer, Simone

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Small Molecule Carboxylates Inhibit Metallo-β-lactamases and Resensitize Carbapenem-Resistant Bacteria to Meropenem von Tehrani, Kamaleddin H. M. E., Bruchle, Nora C., Wade, Nicola, Mashayekhi, Vida, Pesce, Diego, van Haren, Matthijs J., Martin, Nathaniel

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Darobactine mit Überlegener Antibiotischer Aktivität Generiert durch Strukturgeleitetes Kryo‐EM‐Biosynthese‐Design von Seyfert, Carsten E., Porten, Christoph, Yuan, Biao, Deckarm, Selina, Panter, Fabian, Bader, Chantal D., Coetzee, Janetta, Deschner, Felix, Tehrani, Kamaleddin H. M. E., Higgins, Paul G., Seifert, Harald, Marlovits, Thomas C., Herrmann, Jennifer, Müller, Rolf

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Innentitelbild: Darobactine mit Überlegener Antibiotischer Aktivität Generiert durch Strukturgeleitetes Kryo‐EM‐Biosynthese‐Design (Angew. Chem. 2/2023) von Seyfert, Carsten E., Porten, Christoph, Yuan, Biao, Deckarm, Selina, Panter, Fabian, Bader, Chantal D., Coetzee, Janetta, Deschner, Felix, Tehrani, Kamaleddin H. M. E., Higgins, Paul G., Seifert, Harald, Marlovits, Thomas C., Herrmann, Jennifer, Müller, Rolf

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Inside Cover: Darobactins Exhibiting Superior Antibiotic Activity by Cryo‐EM Structure Guided Biosynthetic Engineering (Angew. Chem. Int. Ed. 2/2023) von Seyfert, Carsten E., Porten, Christoph, Yuan, Biao, Deckarm, Selina, Panter, Fabian, Bader, Chantal D., Coetzee, Janetta, Deschner, Felix, Tehrani, Kamaleddin H. M. E., Higgins, Paul G., Seifert, Harald, Marlovits, Thomas C., Herrmann, Jennifer, Müller, Rolf

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Aminocarboxylic acids related to aspergillomarasmine A (AMA) and ethylenediamine-,′-disuccinic acid (EDDS) are strong zinc-binders and inhibitors of the metallo-beta-lactamase NDM-... von Tehrani, Kamaleddin H. M. E, Fu, Haigen, Brüchle, Nora C, Mashayekhi, Vida, Prats Luján, Alejandro, van Haren, Matthijs J, Poelarends, Gerrit J, Martin, Nathaniel I

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Novel Cephalosporin Conjugates Display Potent and Selective Inhibition of Imipenemase-Type Metallo-beta-Lactamases von Tehrani, Kamaleddin H. M. E, Wade, Nicola, Mashayekhi, Vida, Bruchle, Nora C, Jespers, Willem, Voskuil, Koen, Pesce, Diego, van Haren, Matthijs J, van Westen, Gerard J. P, Martin, Nathaniel, I

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