Rings in Clinical Trials and Drugs: Present and Future von Shearer, Jonathan, Castro, Jose L., Lawson, Alastair D. G., MacCoss, Malcolm, Taylor, Richard D.

Volltext

Water molecules at protein-drug interfaces: computational prediction and analysis methods von Samways, Marley L, Taylor, Richard D, Bruce Macdonald, Hannah E, Essex, Jonathan W

Volltext

The next stage of U.S. communications policy: The emerging embedded infosphere von Taylor, Richard D.

Volltext

Rings in drugs von Taylor, Richard D, MacCoss, Malcolm, Lawson, Alastair D G

Volltext

Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR von Stöppler, Daniel, Macpherson, Alex, Smith-Penzel, Susanne, Basse, Nicolas, Lecomte, Fabien, Deboves, Hervé, Taylor, Richard D, Norman, Tim, Porter, John, Waters, Lorna C, Westwood, Marta, Cossins, Ben, Cain, Katharine, White, James, Griffin, Robert, Prosser, Christine, Kelm, Sebastian, Sullivan, Amy H, Fox, 3rd, David, Carr, Mark D, Henry, Alistair, Taylor, Richard, Meier, Beat H, Oschkinat, Hartmut, Lawson, Alastair D

Volltext

Improved protein-ligand docking using GOLD von Verdonk, Marcel L., Cole, Jason C., Hartshorn, Michael J., Murray, Christopher W., Taylor, Richard D.

Volltext

Quantum Artificial Intelligence: A “precautionary” U.S. approach? von Taylor, Richard D.

Volltext

“Data localization”: The internet in the balance von Taylor, Richard D.

Volltext

Comparing protein-ligand docking programs is difficult von Cole, Jason C., Murray, Christopher W., Nissink, J. Willem M., Taylor, Richard D., Taylor, Robin

Volltext

Computational design of an epitope-specific Keap1 binding antibody using hotspot residues grafting and CDR loop swapping von Liu, Xiaofeng, Taylor, Richard D., Griffin, Laura, Coker, Shu-Fen, Adams, Ralph, Ceska, Tom, Shi, Jiye, Lawson, Alastair D. G., Baker, Terry

Volltext

Higher Affinity Antibodies Bind With Lower Hydration and Flexibility in Large Scale Simulations von Wong, Mabel T Y, Kelm, Sebastian, Liu, Xiaofeng, Taylor, Richard D, Baker, Terry, Essex, Jonathan W

Volltext

Corrigendum: Higher Affinity Antibodies Bind With Lower Hydration and Flexibility in Large Scale Simulations von Wong, Mabel T. Y., Kelm, Sebastian, Liu, Xiaofeng, Taylor, Richard D., Baker, Terry, Essex, Jonathan W.

Volltext

Combining Molecular Scaffolds from FDA Approved Drugs: Application to Drug Discovery von Taylor, Richard D, MacCoss, Malcolm, Lawson, Alastair D G

Volltext

Virtual Screening Using Protein−Ligand Docking:  Avoiding Artificial Enrichment von Verdonk, Marcel L, Berdini, Valerio, Hartshorn, Michael J, Mooij, Wijnand T. M, Murray, Christopher W, Taylor, Richard D, Watson, Paul

Volltext

Open Binding Pose Metadynamics: An Effective Approach for the Ranking of Protein–Ligand Binding Poses von Lukauskis, Dominykas, Samways, Marley L., Aureli, Simone, Cossins, Benjamin P., Taylor, Richard D., Gervasio, Francesco Luigi

Volltext

Water Networks in Complexes between Proteins and FDA-Approved Drugs von Samways, Marley L., Bruce Macdonald, Hannah E., Taylor, Richard D., Essex, Jonathan W.

Volltext

Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362 von Lowe, Martin A., Cardenas, Alvaro, Valentin, Jean-Pierre, Zhu, Zhaoning, Abendroth, Jan, Castro, Jose L., Class, Reiner, Delaunois, Annie, Fleurance, Renaud, Gerets, Helga, Gryshkova, Vitalina, King, Lloyd, Lorimer, Donald D., MacCoss, Malcolm, Rowley, Julian H., Rosseels, Marie-Luce, Royer, Leandro, Taylor, Richard D., Wong, Melanie, Zaccheo, Oliver, Chavan, Vishal P., Ghule, Gokul A., Tapkir, Bapusaheb K., Burrows, Jeremy N., Duffey, Maëlle, Rottmann, Matthias, Wittlin, Sergio, Angulo-Barturen, Iñigo, Jiménez-Díaz, María Belén, Striepen, Josefine, Fairhurst, Kate J., Yeo, Tomas, Fidock, David A., Cowman, Alan F., Favuzza, Paola, Crespo-Fernandez, Benigno, Gamo, Francisco Javier, Goldberg, Daniel E., Soldati-Favre, Dominique, Laleu, Benoît, de Haro, Teresa

Volltext

Combining Molecular Scaffolds from FDA Approved Drugs: Application to Drug Discovery: Miniperspective von Taylor, Richard D, MacCoss, Malcolm, Lawson, Alastair D. G

Volltext

The Chemical Synthesis of Knob Domain Antibody Fragments von Macpherson, Alex, Birtley, James R, Broadbridge, Robert J, Brady, Kevin, Schulze, Monika-Sarah E. D, Tang, Yalan, Joyce, Callum, Saunders, Kenneth, Bogle, Gregory, Horton, John, Kelm, Sebastian, Taylor, Richard D, Franklin, Richard J, Selby, Matthew D, Laabei, Maisem, Wonfor, Toska, Hold, Adam, Stanley, Phil, Vadysirisack, Douangsone, Shi, Jiye, van den Elsen, Jean, Lawson, Alastair D. G

Volltext

Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling von Adams, Ralph, Burnley, Rebecca J., Valenzano, Chiara R., Qureshi, Omar, Doyle, Carl, Lumb, Simon, del Carmen Lopez, Maria, Griffin, Robert, McMillan, David, Taylor, Richard D., Meier, Chris, Mori, Prashant, Griffin, Laura M., Wernery, Ulrich, Kinne, Jörg, Rapecki, Stephen, Baker, Terry S., Lawson, Alastair D. G., Wright, Michael, Ettorre, Anna

Volltext