The speed of GTP hydrolysis determines GTP cap size and controls microtubule stability von Roostalu, Johanna, Thomas, Claire, Cade, Nicholas Ian, Kunzelmann, Simone, Taylor, Ian A, Surrey, Thomas

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Structural basis of dimerization and dual W-box DNA recognition by rice WRKY domain von Cheng, Xiankun, Zhao, Yanxiang, Jiang, Qingshan, Yang, Jun, Zhao, Wensheng, Taylor, Ian A, Peng, You-Liang, Wang, Dongli, Liu, Junfeng

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HIV-1 requires capsid remodelling at the nuclear pore for nuclear entry and integration von Guedán, Anabel, Donaldson, Callum D, Caroe, Eve R, Cosnefroy, Ophélie, Taylor, Ian A, Bishop, Kate N

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A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets von Hobor, Fruzsina, Dallmann, Andre, Ball, Neil J., Cicchini, Carla, Battistelli, Cecilia, Ogrodowicz, Roksana W., Christodoulou, Evangelos, Martin, Stephen R., Castello, Alfredo, Tripodi, Marco, Taylor, Ian A., Ramos, Andres

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HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase von Goldstone, David C., Ennis-Adeniran, Valerie, Hedden, Joseph J., Groom, Harriet C. T., Rice, Gillian I., Christodoulou, Evangelos, Walker, Philip A., Kelly, Geoff, Haire, Lesley F., Yap, Melvyn W., de Carvalho, Luiz Pedro S., Stoye, Jonathan P., Crow, Yanick J., Taylor, Ian A., Webb, Michelle

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Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis von Morris, Elizabeth R., Caswell, Sarah J., Kunzelmann, Simone, Arnold, Laurence H., Purkiss, Andrew G., Kelly, Geoff, Taylor, Ian A.

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Mechanism of substrate hydrolysis by the human nucleotide pool sanitiser DNPH1 von Rzechorzek, Neil J., Kunzelmann, Simone, Purkiss, Andrew G., Silva Dos Santos, Mariana, MacRae, James I., Taylor, Ian A., Fugger, Kasper, West, Stephen C.

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A positive‐charged patch and stabilized hydrophobic core are essential for avirulence function of AvrPib in the rice blast fungus von Zhang, Xin, He, Dan, Zhao, Yanxiang, Cheng, Xilan, Zhao, Wensheng, Taylor, Ian A., Yang, Jun, Liu, Junfeng, Peng, You‐Liang

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Structural basis of lentiviral subversion of a cellular protein degradation pathway von Schwefel, David, Groom, Harriet C. T., Boucherit, Virginie C., Christodoulou, Evangelos, Walker, Philip A., Stoye, Jonathan P., Bishop, Kate N., Taylor, Ian A.

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Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis von Acton, Oliver J., Sheppard, Devon, Kunzelmann, Simone, Caswell, Sarah J., Nans, Andrea, Burgess, Ailidh J. O., Kelly, Geoff, Morris, Elizabeth R., Rosenthal, Peter B., Taylor, Ian A.

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Diagnostic accuracy and clinical impact of renal biopsy cytology von Xu, Hongzhi, Taylor‐Cho, Ian A., “Sara” Jiang, Xiaoyin, Foo, Wen‐Chi

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Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction von Arnold, Laurence H, Groom, Harriet C T, Kunzelmann, Simone, Schwefel, David, Caswell, Sarah J, Ordonez, Paula, Mann, Melanie C, Rueschenbaum, Sabrina, Goldstone, David C, Pennell, Simon, Howell, Steven A, Stoye, Jonathan P, Webb, Michelle, Taylor, Ian A, Bishop, Kate N

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Multivalent interactions essential for lentiviral integrase function von Ballandras-Colas, Allison, Chivukula, Vidya, Gruszka, Dominika T., Shan, Zelin, Singh, Parmit K., Pye, Valerie E., McLean, Rebecca K., Bedwell, Gregory J., Li, Wen, Nans, Andrea, Cook, Nicola J., Fadel, Hind J., Poeschla, Eric M., Griffiths, David J., Vargas, Javier, Taylor, Ian A., Lyumkis, Dmitry, Yardimci, Hasan, Engelman, Alan N., Cherepanov, Peter

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Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice von Goldstone, David C., Walker, Philip A., Calder, Lesley J., Coombs, Peter J., Kirkpatrick, Joshua, Ball, Neil J., Hilditch, Laura, Yap, Melvyn W., Rosenthal, Peter B., Stoye, Jonathan P., Taylor, Ian A.

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Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses von Banchenko, Sofia, Krupp, Ferdinand, Gotthold, Christine, Bürger, Jörg, Graziadei, Andrea, O'Reilly, Francis J, Sinn, Ludwig, Ruda, Olga, Rappsilber, Juri, Spahn, Christian M T, Mielke, Thorsten, Taylor, Ian A, Schwefel, David

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Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models von CHANG, Yong S, ADNANE, Jalila, WILKIE, Dean, CARTER, Christopher A, TAYLOR, Ian C. A, LYNCH, Mark, WILHELM, Scott, TRAIL, Pamela A, LEVY, Joan, HENDERSON, Arris, DAHAI XUE, BORTOLON, Elizabeth, ICHETOVKIN, Marina, CHEN, Charles, MCNABOLA, Angela

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Structural basis for Fullerene geometry in a human endogenous retrovirus capsid von Acton, Oliver, Grant, Tim, Nicastro, Giuseppe, Ball, Neil J., Goldstone, David C., Robertson, Laura E., Sader, Kasim, Nans, Andrea, Ramos, Andres, Stoye, Jonathan P., Taylor, Ian A., Rosenthal, Peter B.

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Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control von Cottee, Matthew A., Beckwith, Sean L., Letham, Suzanne C., Kim, Sarah J., Young, George R., Stoye, Jonathan P., Garfinkel, David J., Taylor, Ian A.

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A new class of capsid-targeting inhibitors that specifically block HIV-1 nuclear import von Boulay, Aude, Quevarec, Emmanuel, Malet, Isabelle, Nicastro, Giuseppe, Chamontin, Célia, Perrin, Suzon, Henriquet, Corinne, Pugnière, Martine, Courgnaud, Valérie, Blaise, Mickaël, Marcelin, Anne-Geneviève, Taylor, Ian A, Chaloin, Laurent, Arhel, Nathalie J

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Attenuation of reverse transcriptase facilitates SAMHD1 restriction of HIV-1 in cycling cells von Tsai, Ming-Han C, Caswell, Sarah J, Morris, Elizabeth R, Mann, Melanie C, Pennell, Simon, Kelly, Geoff, Groom, Harriet C T, Taylor, Ian A, Bishop, Kate N

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