EGFR Inhibition Enhances the Cellular Uptake and Antitumor-Activity of the HER3 Antibody-Drug Conjugate HER3-DXd von Haikala, Heidi M, Lopez, Timothy, Köhler, Jens, Eser, Pinar O, Xu, Man, Zeng, Qing, Teceno, Tyler J, Ngo, Kenneth, Zhao, Yutong, Ivanova, Elena V, Bertram, Arrien A, Leeper, Brittaney A, Chambers, Emily S, Adeni, Anika E, Taus, Luke J, Kuraguchi, Mari, Kirschmeier, Paul T, Yu, Channing, Shiose, Yoshinobu, Kamai, Yasuki, Qiu, Yang, Paweletz, Cloud P, Gokhale, Prafulla C, Jänne, Pasi A

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Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity von Mahadevan, Navin R., Knelson, Erik H., Wolff, Jacquelyn O., Vajdi, Amir, Saigi, Maria, Campisi, Marco, Hong, Deli, Thai, Tran C., Piel, Brandon, Han, Saemi, Reinhold, Bruce B., Duke-Cohan, Jonathan S., Poitras, Michael J., Taus, Luke J., Lizotte, Patrick H., Portell, Andrew, Quadros, Victor, Santucci, Alison D., Murayama, Takahiko, Canadas, Israel, Kitajima, Shunsuke, Akitsu, Aoi, Fridrikh, Maya, Watanabe, Hideo, Reardon, Brendan, Gokhale, Prafulla C., Paweletz, Cloud P., Awad, Mark M., Van Allen, Eliezer M., Lako, Ana, Wang, Xi-Tao, Chen, Benjamin, Hong, Fangxin, Sholl, Lynette M., Tolstorukov, Michael Y., Pfaff, Kathleen, Janne, Pasi A., Gjini, Evisa, Edwards, Robin, Rodig, Scott, Reinherz, Ellis L., Oser, Matthew G., Barbie, David A.

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Dynamic single-cell RNA sequencing identifies immunotherapy persister cells following PD-1 blockade von Sehgal, Kartik, Portell, Andrew, Ivanova, Elena, Lizotte, Patrick H., Mahadevan, Navin R., Greene, Jonathan R., Vajdi, Amir, Gurjao, Carino, Teceno, Tyler, Taus, Luke J., Thai, Tran C., Kitajima, Shunsuke, Liu, Derek, Tani, Tetsuo, Noureddine, Moataz, Lau, Christie J., Kirschmeier, Paul T., Liu, David, Giannakis, Marios, Jenkins, Russell W., Gokhale, Prafulla C., Goldoni, Silvia, Pinzon-Ortiz, Maria, Hastings, William D., Hammerman, Peter S., Miret, Juan J., Paweletz, Cloud P., Barbie, David A.

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Combination of Type I and Type II MET Tyrosine Kinase Inhibitors as Therapeutic Approach to Prevent Resistance von Bahcall, Magda, Paweletz, Cloud P, Kuang, Yanan, Taus, Luke J, Sim, Taebo, Kim, Nam Doo, Dholakia, Kshiti H, Lau, Christie J, Gokhale, Prafulla C, Chopade, Pratik R, Hong, Fangxin, Wei, Zihan, Köhler, Jens, Kirschmeier, Paul T, Guo, Jiannan, Guo, Sujuan, Wang, Stephen, Jänne, Pasi A

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Quantification of metastatic load in a syngeneic murine model of metastasis von Taus, Luke J., Flores, Roberto E., Seyfried, Thomas N.

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A High-Throughput Immune-Oncology Screen Identifies EGFR Inhibitors as Potent Enhancers of Antigen-Specific Cytotoxic T-lymphocyte Tumor Cell Killing von Lizotte, Patrick H, Hong, Ruey-Long, Luster, Troy A, Cavanaugh, Megan E, Taus, Luke J, Wang, Stephen, Dhaneshwar, Abha, Mayman, Naomi, Yang, Aaron, Kulkarni, Meghana, Badalucco, Lauren, Fitzpatrick, Erica, Kao, Hsiang-Fong, Kuraguchi, Mari, Bittinger, Mark, Kirschmeier, Paul T, Gray, Nathanael S, Barbie, David A, Jänne, Pasi A

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Abstract 5543: TAK1 deficiency in tumor cells enhances sensitivity to CTL-mediated killing via TNF-α von Miret, Juan J., Luster, Troy A., Lizotte, Patrick, Wu, Min, Nzikoba, Sarah, Taus, Luke Taus J., Gokhale, Prafulla C., Kirschmeier, Paul, Barbie, David, Paweletz, Cloud P.

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Abstract 1483: Ex vivo single cell RNA-sequencing of tumor derived organotypic spheroids identifies a unique mesenchymal resistance program to PD-1 blockade von Portell, Andrew J., Greene, Jonathan, Taus, Luke J., Lizotte, Patrick, Ivanova, Elena, Menezes, Kalil O., Aref, Amir R., Kirschmeier, Paul, Jenkins, Russell W., Barbie, David, Paweletz, Cloud P.

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Abstract 4806: Exploring optimal targeted combination therapies with neratinib for HER2 mutated NSCLC von Kuraguchi, Mari, Taus, Luke J., Zhou, Shan, Avogadri-Connors, Francesca, Cutler, Richard E., Lalani, Alshad S., Kirschmeier, Paul, Jänne, Pasi A.

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Abstract 4935: High-throughput immune-oncology screen identifies EGFR inhibitors as potent enhancers of CTL antigen-specific tumor cell killing von Lizotte, Patrick H., Luster, Troy, Cavanaugh, Megan E., Taus, Luke J., Dhaneshwar, Abha, Mayman, Naomi, Yang, Aaron, Bittinger, Mark, Kirschmeier, Paul, Gray, Nathanael S., Barbie, David A., Janne, Pasi A.

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Use of Ex Vivo Patient-Derived Tumor Organotypic Spheroids to Identify Combination Therapies for HER2 Mutant Non-Small Cell Lung Cancer von Ivanova, Elena, Kuraguchi, Mari, Xu, Man, Portell, Andrew J., Taus, Luke, Diala, Irmina, Lalani, Alshad S., Choi, Jihyun, Chambers, Emily S., Li, Shuai, Liu, Shengwu, Chen, Ting, Barbie, Thanh U., Oxnard, Geoffrey R., Haworth, Jacob J., Wong, Kwok-Kin, Dahlberg, Suzanne E., Aref, Amir A., Barbie, David A., Bahcall, Magda, Paweletz, Cloud P., Janne, Pasi A.

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