Regulation and role of the transcription factor IRF5 in innate immune responses and systemic lupus erythematosus von Ban, Tatsuma, Sato, Go R, Tamura, Tomohiko

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High-mobility group box family of proteins: ligand and sensor for innate immunity von Yanai, Hideyuki, Ban, Tatsuma, Taniguchi, Tadatsugu

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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response von TAKAOKA, Akinori, ZHICHAO WANG, OHBA, Yusuke, TANIGUCHI, Tadatsugu, MYOUNG KWON CHOI, YANAI, Hideyuki, NEGISHI, Hideo, BAN, Tatsuma, YAN LU, MIYAGISHI, Makoto, KODAMA, Tatsuhiko, HONDA, Kenya

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Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation von Kurotaki, Daisuke, Osato, Naoki, Nishiyama, Akira, Yamamoto, Michio, Ban, Tatsuma, Sato, Hideaki, Nakabayashi, Jun, Umehara, Marina, Miyake, Noriko, Matsumoto, Naomichi, Nakazawa, Masatoshi, Ozato, Keiko, Tamura, Tomohiko

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HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses von Tamura, Tomohiko, Yanai, Hideyuki, Lu, Yan, Koshiba, Ryuji, Ronfani, Lorenza, Honda, Kenya, Choi, Myoung Kwon, Kawamura, Takeshi, Bianchi, Marco E, Akira, Shizuo, Nakasato, Makoto, Taniguchi, Tadatsugu, Savitsky, David, Kodama, Tatsuhiko, Negishi, Hideo, Hangai, Sho, Wang, ZhiChao, Ban, Tatsuma

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A RUNX–CBFβ-driven enhancer directs the Irf8 dose-dependent lineage choice between DCs and monocytes von Murakami, Koichi, Sasaki, Haruka, Nishiyama, Akira, Kurotaki, Daisuke, Kawase, Wataru, Ban, Tatsuma, Nakabayashi, Jun, Kanzaki, Satoko, Sekita, Yoichi, Nakajima, Hideaki, Ozato, Keiko, Kimura, Tohru, Tamura, Tomohiko

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Lyn Kinase Suppresses the Transcriptional Activity of IRF5 in the TLR-MyD88 Pathway to Restrain the Development of Autoimmunity von Ban, Tatsuma, Sato, Go R., Nishiyama, Akira, Akiyama, Ai, Takasuna, Marie, Umehara, Marina, Suzuki, Shinsuke, Ichino, Motohide, Matsunaga, Satoko, Kimura, Ayuko, Kimura, Yayoi, Yanai, Hideyuki, Miyashita, Sadakazu, Kuromitsu, Junro, Tsukahara, Kappei, Yoshimatsu, Kentaro, Endo, Itaru, Yamamoto, Tadashi, Hirano, Hisashi, Ryo, Akihide, Taniguchi, Tadatsugu, Tamura, Tomohiko

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Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules von Wang, ZhiChao, Choi, Myoung Kwon, Ban, Tatsuma, Yanai, Hideyuki, Negishi, Hideo, Lu, Yan, Tamura, Tomohiko, Takaoka, Akinori, Nishikura, Kazuko, Taniguchi, Tadatsugu

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Physical and functional interaction among Irf8 enhancers during dendritic cell differentiation von Yamasaki, Takaya, Nishiyama, Akira, Kurogi, Nagomi, Nishimura, Koutarou, Nishida, Shion, Kurotaki, Daisuke, Ban, Tatsuma, Ramilowski, Jordan A., Ozato, Keiko, Toyoda, Atsushi, Tamura, Tomohiko

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Combining IL-6 and SARS-CoV-2 RNAaemia-based risk stratification for fatal outcomes of COVID-19 von Saji, Ryo, Nishii, Mototsugu, Sakai, Kazuya, Miyakawa, Kei, Yamaoka, Yutaro, Ban, Tatsuma, Abe, Takeru, Ohyama, Yutaro, Nakajima, Kento, Hiromi, Taro, Matsumura, Reo, Suzuki, Naoya, Taniguchi, Hayato, Otsuka, Tsuyoshi, Oi, Yasufumi, Ogawa, Fumihiro, Uchiyama, Munehito, Takahashi, Kohei, Iwashita, Masayuki, Kimura, Yayoi, Fujii, Satoshi, Furuya, Ryosuke, Tamura, Tomohiko, Ryo, Akihide, Takeuchi, Ichiro

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Irf5 siRNA-loaded biodegradable lipid nanoparticles ameliorate concanavalin A-induced liver injury von Kawase, Wataru, Kurotaki, Daisuke, Suzuki, Yuta, Ishihara, Hiroshi, Ban, Tatsuma, Sato, Go R., Ichikawa, Juri, Yanai, Hideyuki, Taniguchi, Tadatsugu, Tsukahara, Kappei, Tamura, Tomohiko

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Suppression of immune responses by nonimmunogenic oligodeoxynucleotides with high affinity for high-mobility group box proteins (HMGBs) von Yanai, Hideyuki, Chiba, Shiho, Ban, Tatsuma, Nakaima, Yukana, Onoe, Takashi, Honda, Kenya, Ohdan, Hideki, Taniguchi, Tadatsugu

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Machine learning for prediction of immunotherapeutic outcome in non-small-cell lung cancer based on circulating cytokine signatures von Wei, Feifei, Azuma, Koichi, Nakahara, Yoshiro, Saito, Haruhiro, Matsuo, Norikazu, Tagami, Tomoyuki, Kouro, Taku, Igarashi, Yuka, Tokito, Takaaki, Kato, Terufumi, Kondo, Tetsuro, Murakami, Shuji, Usui, Ryo, Himuro, Hidetomo, Horaguchi, Shun, Tsuji, Kayoko, Murotani, Kenta, Ban, Tatsuma, Tamura, Tomohiko, Miyagi, Yohei, Sasada, Tetsuro

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selective contribution of the RIG-I-like receptor pathway to type I interferon responses activated by cytosolic DNA von Choi, Myoung Kwon, Wang, ZhiChao, Ban, Tatsuma, Yanai, Hideyuki, Lu, Yan, Koshiba, Ryuji, Nakaima, Yukana, Hangai, Sho, Savitsky, David, Nakasato, Makoto, Negishi, Hideo, Takeuchi, Osamu, Honda, Kenya, Akira, Shizuo, Tamura, Tomohiko, Taniguchi, Tadatsugu

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IRF8 inhibits C/EBPα activity to restrain mononuclear phagocyte progenitors from differentiating into neutrophils von Kurotaki, Daisuke, Yamamoto, Michio, Nishiyama, Akira, Uno, Kazuhiro, Ban, Tatsuma, Ichino, Motohide, Sasaki, Haruka, Matsunaga, Satoko, Yoshinari, Masahiro, Ryo, Akihide, Nakazawa, Masatoshi, Ozato, Keiko, Tamura, Tomohiko

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A RUNX-CBF[beta]-driven enhancer directs the Irf8 dose-dependent lineage choice between DCs and monocytes von Murakami, Koichi, Sasaki, Haruka, Nishiyama, Akira, Kurotaki, Daisuke, Kawase, Wataru, Ban, Tatsuma, Nakabayashi, Jun

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Phos-tag Immunoblot Analysis for Detecting IRF5 Phosphorylation von Sato, Go R, Ban, Tatsuma, Tamura, Tomohiko

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Genetic and chemical inhibition of IRF5 suppresses pre-existing mouse lupus-like disease von Ban, Tatsuma, Kikuchi, Masako, Sato, Go R., Manabe, Akio, Tagata, Noriko, Harita, Kayo, Nishiyama, Akira, Nishimura, Kenichi, Yoshimi, Ryusuke, Kirino, Yohei, Yanai, Hideyuki, Matsumoto, Yoshiko, Suzuki, Shuichi, Hihara, Hiroe, Ito, Masashi, Tsukahara, Kappei, Yoshimatsu, Kentaro, Yamamoto, Tadashi, Taniguchi, Tadatsugu, Nakajima, Hideaki, Ito, Shuichi, Tamura, Tomohiko

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Multi-omics analysis-based clinical and functional significance of a novel prognostic and immunotherapeutic gene signature derived from amino acid metabolism pathways in lung adeno... von Huihui Xiang, Huihui Xiang, Rika Kasajima, Rika Kasajima, Koichi Azuma, Tomoyuki Tagami, Asami Hagiwara, Yoshiro Nakahara, Yoshiro Nakahara, Haruhiro Saito, Yuka Igarashi, Yuka Igarashi, Feifei Wei, Feifei Wei, Tatsuma Ban, Mitsuyo Yoshihara, Mitsuyo Yoshihara, Yoshiyasu Nakamura, Yoshiyasu Nakamura, Shinya Sato, Shinya Sato, Shinya Sato, Shiro Koizume, Shiro Koizume, Tomohiko Tamura, Tetsuro Sasada, Tetsuro Sasada, Yohei Miyagi, Yohei Miyagi

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IRF8 inhibits the activity of C/EBPα to restrain mononuclear phagocyte progenitors from differentiating into neutrophils von Kurotaki, Daisuke, Yamamoto, Michio, Nishiyama, Akira, Uno, Kazuhiro, Ban, Tatsuma, Ichino, Motohide, Sasaki, Haruka, Matsunaga, Satoko, Yoshinari, Masahiro, Ryo, Akihide, Nakazawa, Masatoshi, Ozato, Keiko, Tamura, Tomohiko

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