S46 Activation of TGF-  by airway smooth muscle cells via the  V 5 integrin in asthmatic airway remodelling von Tatler, A. L., John, A. E., Jolly, L., Knox, A. J., Pang, L., Jenkins, G.

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S32 Loss/inhibition of the aVb5 integrin reduces allergen-induced increases in airway smooth muscle mass in in vivo models of asthma von Tatler, A. L., John, A. E., Jolly, L., Habgood, A., Porte, J., Knox, A. J., Huang, X., Sheppard, D., Jenkins, G.

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Pathobiology of Airway Remodeling in Asthma: The Emerging Role of Integrins von Joseph, Chitra, Tatler, Amanda L

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A19 THE EXTRACELLULAR MATRIX: A STICKY SITUATION: Extracellular Matrix Deposited By Asthmatic Human Airway Smooth Muscle Cells Enhances Basal Activation Of Tgfβ von John, A E, Krishnan, R, Brightling, C E, Shaw, D, Jenkins, R G, Tatler, A L

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COVID-19 and pulmonary fibrosis: a potential role for lung epithelial cells and fibroblasts von John, AE, Joseph, C, Jenkins, G, Tatler, AL

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B56 SCAR WARS: INSIGHTS INTO MECHANISMS AND TREATMENTS OF PULMONARY FIBROSIS: Caffeine Inhibits Tgfâ Activation In Lung Epithelial Cells And Reduces Pulmonary Fibrosis In Ex Vivo P... von Tatler, A L, Barnes, J L, Habgood, A, Krishnan, R, McAnulty, R J, Jenkins, G

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D97 WELCOME BACK: ALVEOLAR MACROPHAGES IN PULMONARY FIBROSIS: Loss Of Epithelial Gq/11 Signaling In The Lung Leads To Il-33 Mediated M2 Macrophage Polarization And Loss Of Tgf[Beta... von John, A E, Stavrou, A, Tatler, A L, Porte, J, Habgood, A, Knox, A J, Offermanns, S, Jenkins, R G

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D97 IMAGING AND MODELING: INSIGHTS INTO LUNG STRUCTURE AND FUNCTION: Biomechanical Model Of Inflammation-Induced Airway Smooth Muscle Mass Accumulation And Extracellular Matrix Dep... von Hill, M R, Tatler, A L, O'Dea, R D, Billington, C K, John, A E, Deacon, K, Johnson, S R, Brook, B S

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Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation von Goodwin, AT, John, AE, Joseph, C, Habgood, A, Tatler, AL, Susztak, K, Palmer, M, Offermanns, S, Henderson, NC, Jenkins, RG

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A60 LUNG FIBROSIS: ANIMAL MODELS I: Influenza Infection, But Not Rhinovirus Infection, May Cause Exacerbation Of Lung Fibrosis Through Lung Collagen Deposition von Stavrou, A, Jolly, L, Glanville, N, Habgood, A, Porte, J, Tatler, A L, Johnston, S L, Blanchard, A, Jenkins, G

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C109 LUNG BIOLOGY: AT A CROSSROAD BETWEEN INJURY AND REPAIR: Epithelial Gq/g11 Signaling, But Not G12/g13, Is Required For Alveolar Tgf[Beta] Activation And Homeostasis von John, A E, Tatler, A L, Habgood, A, Porte, J, Jolly, L, Knox, A J, Offermanns, S, Jenkins, R G

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A60 LUNG FIBROSIS: ANIMAL MODELS I: Investigating The Role Of Secretory Leukocyte Protease Inhibitor On The Development Of Pulmonary Fibrosis von Habgood, A, Tatler, A L, John, A E, Laurent, G J, Wahl, S M, Johnson, S R, Jenkins, R G

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S75 Cyclical stretch induces g[alpha]q/11 mediated tgf[beta] activation in lung fibroblasts von Goodwin, AT, Tatler, AL, Offermanns, S, Jenkins, G

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S75 Cyclical stretch induces gαq/11 mediated tgfβ activation in lung fibroblasts von Goodwin, AT, Tatler, AL, Offermanns, S, Jenkins, G

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Differential remodeling in small and large murine airways revealed by novel whole lung airway analysis von Tatler, AL, Philp, CJ, Hill, MR, Cox, S, Bullock, AM, Habgood, A, John, A, Middlewick, R, Stephenson, KE, Goodwin, AT, Billington, CK, O'Dea, RD, Johnson, SR, Brook, BS

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S80 Cyclical mechanical stretch regulates alveologenesis via mesenchymal Gαq/11-Mediated TGFβ2 signalling von Goodwin, AT, John, AE, Joseph, C, Habgood, A, Tatler, AL, Offermanns, S, Henderson, NC, Jenkins, G

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Lysyl oxidase-like 2 is increased in asthma and contributes to asthmatic airway remodelling von Ramis, J, Middlewick, R, Pappalardo, F, Cairns, JT, Stewart, ID, John, AE, Naveed, S-U-N, Krishnan, R, Miller, S, Shaw, DE, Brightling, CE, Buttery, L, Rose, F, Jenkins, G, Johnson, SR, Tatler, AL

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B61 POTPOURRI OF INJ-OURRI: EPITHELIAL CELLS IN LUNG INJURY AND REPAIR: Identification Of A Novel Region Of The Itgb6 Promoter Responsible For Basal Repression Of Itgb6 Transcripti... von Tatler, A L, Goodwin, A, Porte, J, Gbolahan, O, Clifford, R L, Weinreb, P, Violette, S, Gauldie, J, Kolb, M R J, Parfrey, H, Wolters, P J, Laurent, G, Jenkins, G

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S46 Activation of TGF-β by airway smooth muscle cells via the αVβ5 integrin in asthmatic airway remodelling von Tatler, A L, John, A E, Jolly, L, Knox, A J, Pang, L, Jenkins, G

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S123 Mononuclear inflammation and disruption of normal alveolar structure following deletion of G q/11, but not G 12/13, in type II alveolar epithelial cells von John, A. E., Porte, J., Jolly, L., Tatler, A. L., Jenkins, R. G.

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