IL-6 Mediates Cross-Talk between Tumor Cells and Activated Fibroblasts in the Tumor Microenvironment von Karakasheva, Tatiana A, Lin, Eric W, Tang, Qiaosi, Qiao, Edmund, Waldron, Todd J, Soni, Monica, Klein-Szanto, Andres J, Sahu, Varun, Basu, Devraj, Ohashi, Shinya, Baba, Kiichiro, Giaccone, Zachary T, Walker, Sarah R, Frank, David A, Wileyto, E Paul, Long, Qi, Dunagin, Margaret C, Raj, Arjun, Diehl, J Alan, Wong, K K, Bass, Adam J, Rustgi, Anil K

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Geometric engineering of organoid culture for enhanced organogenesis in a dish von Park, Sunghee Estelle, Kang, Shawn, Paek, Jungwook, Georgescu, Andrei, Chang, Jeehan, Yi, Alex Yoon, Wilkins, Benjamin J., Karakasheva, Tatiana A., Hamilton, Kathryn E., Huh, Dan Dongeun

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CD38-Expressing Myeloid-Derived Suppressor Cells Promote Tumor Growth in a Murine Model of Esophageal Cancer von Karakasheva, Tatiana A, Waldron, Todd J, Eruslanov, Evgeniy, Kim, Sang-Bae, Lee, Ju-Seog, O'Brien, Shaun, Hicks, Philip D, Basu, Devraj, Singhal, Sunil, Malavasi, Fabio, Rustgi, Anil K

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Comparative transcriptomes of adenocarcinomas and squamous cell carcinomas reveal molecular similarities that span classical anatomic boundaries von Lin, Eric W, Karakasheva, Tatiana A, Lee, Dong-Jin, Lee, Ju-Seog, Long, Qi, Bass, Adam J, Wong, Kwok K, Rustgi, Anil K

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Patient-derived organoids as a platform for modeling a patient’s response to chemoradiotherapy in esophageal cancer von Karakasheva, Tatiana A., Gabre, Joel T., Sachdeva, Uma M., Cruz-Acuña, Ricardo, Lin, Eric W., DeMarshall, Maureen, Falk, Gary W., Ginsberg, Gregory G., Yang, Zhaohai, Kim, Michele M., Diffenderfer, Eric S., Pitarresi, Jason R., Li, Jinyang, Muir, Amanda B., Hamilton, Kathryn E., Nakagawa, Hiroshi, Bass, Adam J., Rustgi, Anil K.

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Generation and Characterization of Patient‐Derived Head and Neck, Oral, and Esophageal Cancer Organoids von Karakasheva, Tatiana A., Kijima, Takashi, Shimonosono, Masataka, Maekawa, Hisatsugu, Sahu, Varun, Gabre, Joel T., Cruz‐Acuña, Ricardo, Giroux, Veronique, Sangwan, Veena, Whelan, Kelly A., Natsugoe, Shoji, Yoon, Angela J., Philipone, Elizabeth, Klein‐Szanto, Andres J., Ginsberg, Gregory G., Falk, Gary W., Abrams, Julian A., Que, Jianwen, Basu, Devraj, Ferri, Lorenzo, Diehl, J. Alan, Bass, Adam J., Wang, Timothy C., Rustgi, Anil K., Nakagawa, Hiroshi

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CD38+ M-MDSC expansion characterizes a subset of advanced colorectal cancer patients von Karakasheva, Tatiana A, Dominguez, George A, Hashimoto, Ayumi, Lin, Eric W, Chiu, Christopher, Sasser, Kate, Lee, Jae W, Beatty, Gregory L, Gabrilovich, Dmitry I, Rustgi, Anil K

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Modeling Epithelial Homeostasis and Reactive Epithelial Changes in Human and Murine Three‐Dimensional Esophageal Organoids von Nakagawa, Hiroshi, Kasagi, Yuta, Karakasheva, Tatiana A., Hara, Takeo, Aaron, Bailey, Shimonosono, Masataka, Kijima, Takashi, Giroux, Veronique, Bailey, Dominique, Wilkins, Benjamin, Abrams, Julian A., Falk, Gary W., Aceves, Seema S., Spergel, Jonathan M., Hamilton, Kathryn E., Whelan, Kelly A., Muir, Amanda B.

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Patient-derived Colonoids From Disease-spared Tissue Retain Inflammatory Bowel Disease-specific Transcriptomic Signatures von Karakasheva, Tatiana A., Zhou, Yusen, Xie, Hongbo M., Soto, Gloria E., Johnson, Tiana D., Stoltz, Madison A., Roach, Daana M., Nema, Noor, Umeweni, Chizoba N., Naughton, Kaitlyn, Dolinsky, Lauren, Pippin, James A., Wells, Andrew D., Grant, Struan F.A., Ghanem, Louis, Terry, Natalie, Muir, Amanda B., Hamilton, Kathryn E.

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Tumor-Derived CCL5 Recruits Cancer-Associated Fibroblasts and Promotes Tumor Cell Proliferation in Esophageal Squamous Cell Carcinoma von Dunbar, Karen J, Karakasheva, Tatiana A, Tang, Qiaosi, Efe, Gizem, Lin, Eric W, Harris, Michael, Sahu, Varun, Sachdeva, Uma M, Hu, Jianhua, Klein-Szanto, Andres J, Henick, Brian, Diehl, J Alan, Nakagawa, Hiroshi, Rustgi, Anil K

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Epithelial-Fibroblast Crosstalk in Eosinophilic Esophagitis von Muir, Amanda B., Karakasheva, Tatiana A., Whelan, Kelly A.

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Intestinal epithelial autophagy is required for the regenerative benefit of calorie restriction von Williams, Patrick A, Naughton, Kaitlyn E, Simon, Lauren A, Soto, Gloria E, Parham, Louis R, Ma, Xianghui, Danan, Charles H, Hu, Weiming, Friedman, Elliot S, McMillan, Emily A, Mehta, Hritik, Stoltz, Madison A, Ocaña, Joshua Soto, Zackular, Joseph P, Bittinger, Kyle, Whelan, Kelly A, Karakasheva, Tatiana A, Hamilton, Kathryn E

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Colonoids From Patients With Pediatric Inflammatory Bowel Disease Exhibit Decreased Growth Associated With Inflammation Severity and Durable Upregulation of Antigen Presentation Ge... von Kelsen, Judith R, Dawany, Noor, Conrad, Maire A, Karakasheva, Tatiana A, Maurer, Kelly, Wei, Jane M, Uman, Selen, Dent, Maiah H, Behera, Rithika, Bryant, Laura M, Ma, Xianghui, Moreira, Leticia, Chatterji, Priya, Shraim, Rawan, Merz, Audrey, Mizuno, Rei, Simon, Lauren A, Muir, Amanda B, Giraudo, Claudio, Behrens, Edward M, Whelan, Kelly A, Devoto, Marcella, Russo, Pierre A, Andres, Sarah F, Sullivan, Kathleen E, Hamilton, Kathryn E

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Myeloid derived suppressor cells: Targets for therapy von Waldron, Todd J., Quatromoni, Jon G., Karakasheva, Tatiana A., Singhal, Sunil, Rustgi, Anil K.

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Lysyl Oxidase Regulates Epithelial Differentiation and Barrier Integrity in Eosinophilic Esophagitis von Sasaki, Masaru, Hara, Takeo, Wang, Joshua X., Zhou, Yusen, Kennedy, Kanak V., Umeweni, Chizoba N., Alston, Maiya A., Spergel, Zachary C., Ishikawa, Satoshi, Teranishi, Ryugo, Nakagawa, Ritsu, Mcmillan, Emily A., Whelan, Kelly A., Karakasheva, Tatiana A., Hamilton, Kathryn E., Ruffner, Melanie A., Muir, Amanda B.

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CD73+ Epithelial Progenitor Cells That Contribute to Homeostasis and Renewal Are Depleted in Eosinophilic Esophagitis von Hara, Takeo, Kasagi, Yuta, Wang, Joshua, Sasaki, Masaru, Aaron, Bailey, Karami, Adam, Shimonosono, Masataka, Shimonosono, Rieko, Maekawa, Hisatsugu, Dolinsky, Lauren, Wilkins, Benjamin, Klein, Jeremy, Wei, Jane, Nunes, Kathryn, Lynch, Kristle, Spergel, Jonathan M., Hamilton, Kathryn E., Ruffner, Melanie A., Karakasheva, Tatiana A., Whelan, Kelly A., Nakagawa, Hiroshi, Muir, Amanda B.

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The tumor microenvironment in esophageal cancer von Lin, E W, Karakasheva, T A, Hicks, P D, Bass, A J, Rustgi, A K

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528 FORKHEAD BOX PROTEIN M1 REGULATES FIBROBLAST FUNCTION IN EOSINPHILIC ESOPHAGITIS von Teranishi, Ryugo, Sasaki, Masaru, Kennedy, Kanak V., Wang, Joshua X., Ishikawa, Satoshi, Karakasheva, Tatiana A., Muir, Amanda B.

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778 THE CD73-ADENOSINE AXIS PROMOTES DIFFERENTIATION OF ESOPHAGEAL EPITHELIUM IN EOSINOPHILIC ESOPHAGITIS von Ishikawa, Satoshi, Wang, Joshua X., Kennedy, Kanak V., Teranishi, Ryugo, McMillan, Emily A., Wechsler, Joshua B., Ruffner, Melanie A., Karakasheva, Tatiana A., Whelan, Kelly A., Muir, Amanda B.

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862 LYSYL OXIDASE (LOX) REGULATES EPITHELIAL PROLIFERATION AND DIFFERENTIATION IN EOSINOPHILIC ESOPHAGITIS von Kennedy, Kanak V., Wang, Joshua X., Teranishi, Ryugo, Sasaki, Masaru, Ishikawa, Satoshi, Umeweni, Chizoba N., Alston, Maiya, Nakagawa, Ritsu, McMillan, Emily A., Karakasheva, Tatiana A., Muir, Amanda B.

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