Dynamic Protein Acylation: New Substrates, Mechanisms, and Drug Targets von Lanyon-Hogg, Thomas, Faronato, Monica, Serwa, Remigiusz A., Tate, Edward W.

Volltext

Global profiling of co- and post-translationally N-myristoylated proteomes in human cells von Thinon, Emmanuelle, Serwa, Remigiusz A., Broncel, Malgorzata, Brannigan, James A., Brassat, Ute, Wright, Megan H., Heal, William P., Wilkinson, Anthony J., Mann, David J., Tate, Edward W.

Volltext

High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation von Dian, Cyril, Pérez-Dorado, Inmaculada, Rivière, Frédéric, Asensio, Thomas, Legrand, Pierre, Ritzefeld, Markus, Shen, Mengjie, Cota, Ernesto, Meinnel, Thierry, Tate, Edward W., Giglione, Carmela

Volltext

Global profiling of protein lipidation using chemical proteomic technologies von Tate, Edward W, Kalesh, Karunakaran A, Lanyon-Hogg, Thomas, Storck, Elisabeth M, Thinon, Emmanuelle

Volltext

Structural basis for membrane attack complex inhibition by CD59 von Couves, Emma C., Gardner, Scott, Voisin, Tomas B., Bickel, Jasmine K., Stansfeld, Phillip J., Tate, Edward W., Bubeck, Doryen

Volltext

Activity-based probes: discovering new biology and new drug targets von Heal, William P, Dang, T. H. Tam, Tate, Edward W

Volltext

Discovery of lipid-mediated protein-protein interactions in living cells using metabolic labeling with photoactivatable clickable probes von Fedoryshchak, Roman O, Gorelik, Andrii, Shen, Mengjie, Shchepinova, Maria M, Pérez-Dorado, Inmaculada, Tate, Edward W

Volltext

High‐Throughput Kinetic Analysis for Target‐Directed Covalent Ligand Discovery von Craven, Gregory B., Affron, Dominic P., Allen, Charlotte E., Matthies, Stefan, Greener, Joe G., Morgan, Rhodri M. L., Tate, Edward W., Armstrong, Alan, Mann, David J.

Volltext

Multifunctional Reagents for Quantitative Proteome-Wide Analysis of Protein Modification in Human Cells and Dynamic Profiling of Protein Lipidation During Vertebrate Development von Broncel, Malgorzata, Serwa, Remigiusz A., Ciepla, Paulina, Krause, Eberhard, Dallman, Margaret J., Magee, Anthony I., Tate, Edward W.

Volltext

Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach von Wright, Megan H., Clough, Barbara, Rackham, Mark D., Rangachari, Kaveri, Brannigan, James A., Grainger, Munira, Moss, David K., Bottrill, Andrew R., Heal, William P., Broncel, Malgorzata, Serwa, Remigiusz A., Brady, Declan, Mann, David J., Leatherbarrow, Robin J., Tewari, Rita, Wilkinson, Anthony J., Holder, Anthony A., Tate, Edward W.

Volltext

Inhibition of vaccinia virus L1 N-myristoylation by the host N-myristoyltransferase inhibitor IMP-1088 generates non-infectious virions defective in cell entry von Priyamvada, Lalita, Kallemeijn, Wouter W, Faronato, Monica, Wilkins, Kimberly, Goldsmith, Cynthia S, Cotter, Catherine A, Ojeda, Suany, Solari, Roberto, Moss, Bernard, Tate, Edward W, Satheshkumar, Panayampalli Subbian

Volltext

Validation and Invalidation of Chemical Probes for the Human N-myristoyltransferases von Kallemeijn, Wouter W., Lueg, Gregor A., Faronato, Monica, Hadavizadeh, Kate, Goya Grocin, Andrea, Song, Ok-Ryul, Howell, Michael, Calado, Dinis P., Tate, Edward W.

Volltext

d-Cycloserine destruction by alanine racemase and the limit of irreversible inhibition von de Chiara, Cesira, Homšak, Miha, Prosser, Gareth A., Douglas, Holly L., Garza-Garcia, Acely, Kelly, Geoff, Purkiss, Andrew G., Tate, Edward W., de Carvalho, Luiz Pedro S.

Volltext

Building bridges for highly selective, potent and stable oxytocin and vasopressin analogs von Beard, Rhiannon, Stucki, Andy, Schmitt, Muriel, Py, Gabrielle, Grundschober, Christophe, Gee, Antony D., Tate, Edward W.

Volltext

Multifunctional protein labeling via enzymatic N-terminal tagging and elaboration by click chemistry von Heal, William P, Wright, Megan H, Thinon, Emmanuelle, Tate, Edward W

Volltext

Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins von Alzahofi, Noura, Welz, Tobias, Robinson, Christopher L., Page, Emma L., Briggs, Deborah A., Stainthorp, Amy K., Reekes, James, Elbe, David A., Straub, Felix, Kallemeijn, Wouter W., Tate, Edward W., Goff, Philip S., Sviderskaya, Elena V., Cantero, Marta, Montoliu, Lluis, Nedelec, Francois, Miles, Amanda K., Bailly, Maryse, Kerkhoff, Eugen, Hume, Alistair N.

Volltext

Photochemical Probe Identification of a Small‐Molecule Inhibitor Binding Site in Hedgehog Acyltransferase (HHAT) von Lanyon‐Hogg, Thomas, Ritzefeld, Markus, Zhang, Leran, Andrei, Sebastian A., Pogranyi, Balazs, Mondal, Milon, Sefer, Lea, Johnston, Callum D., Coupland, Claire E., Greenfield, Jake L., Newington, Joshua, Fuchter, Matthew J., Magee, Anthony I., Siebold, Christian, Tate, Edward W.

Volltext

Target profiling of zerumbone using a novel cell-permeable clickable probe and quantitative chemical proteomics von Kalesh, Karunakaran A, Clulow, James A, Tate, Edward W

Volltext

Genome-wide Functional Analysis of Plasmodium Protein Phosphatases Reveals Key Regulators of Parasite Development and Differentiation von Guttery, David S., Poulin, Benoit, Ramaprasad, Abhinay, Wall, Richard J., Ferguson, David J.P., Brady, Declan, Patzewitz, Eva-Maria, Whipple, Sarah, Straschil, Ursula, Wright, Megan H., Mohamed, Alyaa M.A.H., Radhakrishnan, Anand, Arold, Stefan T., Tate, Edward W., Holder, Anthony A., Wickstead, Bill, Pain, Arnab, Tewari, Rita

Volltext

Dynamics and Molecular Interactions of GPI-Anchored CD59 von Voisin, Tomas B, Couves, Emma C, Tate, Edward W, Bubeck, Doryen

Volltext