Structure of a flavonoid glucosyltransferase reveals the basis for plant natural product modification von Offen, W, Martinez-Fleites, C, Yang, M, Kiat-Lim, E, Davis, B.G, Tarling, C.A, Ford, C.M, Bowles, D.J, Davies, G.J

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Chitinase Inhibition by Chitobiose and Chitotriose Thiazolines von Macdonald, James M, Tarling, Chris A, Taylor, Edward J, Dennis, Rebecca J, Myers, David S, Knapp, Spencer, Davies, Gideon J, Withers, Stephen G

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Fluorous Iminoalditols: A New Family of Glycosidase Inhibitors and Pharmacological Chaperones von Schitter, Georg, Steiner, Andreas J, Pototschnig, Gerit, Scheucher, Elisabeth, Thonhofer, Martin, Tarling, Chris A, Withers, Stephen G, Fantur, Katrin, Paschke, Eduard, Mahuran, Don J, Rigat, Brigitte A, Tropak, Michael B, Illaszewicz, Carina, Saf, Robert, Stütz, Arnold E, Wrodnigg, Tanja M

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The Structural Basis of Glycosidase Inhibition by Five-Membered Iminocyclitols: The Clan A Glycoside Hydrolase Endoglycoceramidase as a Model System von Caines, Matthew E. C., Hancock, Susan M., Tarling, Chris A., Wrodnigg, Tanja M., Stick, Robert V., Stütz, Arnold E., Vasella, Andrea, Withers, Stephen G., Strynadka, Natalie C. J.

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Direct Observation of the Protonation State of an Imino Sugar Glycosidase Inhibitor upon Binding von Varrot, Annabelle, Tarling, Chris A, Macdonald, James M, Stick, Robert V, Zechel, David L, Withers, Stephen G, Davies, Gideon J

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Structural and Mechanistic Analyses of endo-Glycoceramidase II, a Membrane-associated Family 5 Glycosidase in the Apo and GM3 Ganglioside-bound Forms von Caines, Matthew E.C., Vaughan, Mark D., Tarling, Chris A., Hancock, Susan M., Warren, R. Antony J., Withers, Stephen G., Strynadka, Natalie C.J.

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Search for Novel Human Pancreatic α-Amylase Inhibitors: High-Throughput Screening of Terrestrial and Marine Natural Product Extracts von Tarling, Chris A, Woods, Kate, Zhang, Ran, Brastianos, Harry C, Brayer, Gary D, Andersen, Raymond J, Withers, Stephen G

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Synthesis of lipophilic 1-deoxygalactonojirimycin derivatives as D-galactosidase inhibitors von Schitter, Georg, Scheucher, Elisabeth, Steiner, Andreas J, Stütz, Arnold E, Thonhofer, Martin, Tarling, Chris A, Withers, Stephen G, Wicki, Jacqueline, Fantur, Katrin, Paschke, Eduard, Mahuran, Don J, Rigat, Brigitte A, Tropak, Michael, Wrodnigg, Tanja M

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Crystal structure of Thermotoga maritima alpha-L-fucosidase. Insights into the catalytic mechanism and the molecular basis for fucosidosis von Sulzenbacher, Gerlind, Bignon, Christophe, Nishimura, Takeshi, Tarling, Chris A, Withers, Stephen G, Henrissat, Bernard, Bourne, Yves

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Structural Analysis of Golgi α-Mannosidase II Inhibitors Identified from a Focused Glycosidase Inhibitor Screen von Kuntz, Douglas A, Tarling, Chris A, Withers, Stephen G, Rose, David R

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The donor subsite of trehalose-6-phosphate synthase: binary complexes with UDP-glucose and UDP-2-deoxy-2-fluoro-glucose at 2 A resolution von Gibson, Robert P, Tarling, Chris A, Roberts, Shirley, Withers, Stephen G, Davies, Gideon J

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Recruitment of Both Uniform and Differential Binding Energy in Enzymatic Catalysis:  Xylanases from Families 10 and 11 von Wicki, Jacqueline, Schloegl, Johann, Tarling, Chris A, Withers, Stephen G

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X-ray Crystal Structures of Rabbit N-acetylglucosaminyltransferase I (GnT I) in Complex with Donor Substrate Analogues von Gordon, Roni D., Sivarajah, Prashanth, Satkunarajah, Malathy, Ma, Dengbo, Tarling, Chris A., Vizitiu, Dragos, Withers, Stephen G., Rini, James M.

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Identification of the catalytic nucleophile of the family 29 alpha-L-fucosidase from Thermotoga maritima through trapping of a covalent glycosyl-enzyme intermediate and mutagenesis von Tarling, Chris A, He, Shouming, Sulzenbacher, Gerlind, Bignon, Christophe, Bourne, Yves, Henrissat, Bernard, Withers, Stephen G

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High-throughput screening of cell lysates for ganglioside synthesis von Hancock, Susan M., Tarling, Chris A., Withers, Stephen G.

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Probing Electrostatic Interactions along the Reaction Pathway of a Glycoside Hydrolase:  Histidine Characterization by NMR Spectroscopy von Schubert, Mario, Poon, David K. Y, Wicki, Jacqueline, Tarling, Chris A, Kwan, Emily M, Nielsen, Jens E, Withers, Stephen G, McIntosh, Lawrence P

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2-Acetamino-1,2-dideoxynojirimycin—lysine hybrids as hexosaminidase inhibitors von Steiner, Andreas J., Schitter, Georg, Stütz, Arnold E., Wrodnigg, Tanja M., Tarling, Chris A., Withers, Stephen G., Mahuran, Don J., Tropak, Michael B.

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1-Deoxygalactonojirimycin-lysine hybrids as potent d-galactosidase inhibitors von Steiner, Andreas J., Schitter, Georg, Stütz, Arnold E., Wrodnigg, Tanja M., Tarling, Chris A., Withers, Stephen G., Fantur, Katrin, Mahuran, Don, Paschke, Eduard, Tropak, Michael

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Iminoalditol-amino acid hybrids: synthesis and evaluation as glycosidase inhibitors von Steiner, Andreas J., Stütz, Arnold E., Tarling, Chris A., Withers, Stephen G., Wrodnigg, Tanja M.

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Structural, thermodynamic, and kinetic analyses of tetrahydrooxazine-derived inhibitors bound to beta-glucosidases von Gloster, Tracey M, Macdonald, James M, Tarling, Chris A, Stick, Robert V, Withers, Stephen G, Davies, Gideon J

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