Cutting Edge: DNase II deficiency prevents activation of autoreactive B cells by double-stranded DNA endogenous ligands von Pawaria, Sudesh, Moody, Krishna, Busto, Patricia, Nündel, Kerstin, Choi, Chee-Ho, Ghayur, Tariq, Marshak-Rothstein, Ann

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Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin von Wu, Chengbin, Ying, Hua, Grinnell, Christine, Bryant, Shaughn, Miller, Renee, Clabbers, Anca, Bose, Sahana, McCarthy, Donna, Zhu, Rong-Rong, Santora, Ling, Davis-Taber, Rachel, Kunes, Yune, Fung, Emma, Schwartz, Annette, Sakorafas, Paul, Gu, Jijie, Tarcsa, Edit, Murtaza, Anwar, Ghayur, Tariq

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CRISPR/Cas9-targeting of CD40 in hematopoietic stem cells limits immune activation mediated by anti-CD40 von Wang, Rui, Graham, Sean, Sun, Ning, McCarthy, Donna, Peng, Ruoqi, Erickson, Jamie, Oconnor, Liz, Zhu, Xiaochun, Wurbel, Marc, Dunstan, Robert, Westmoreland, Susan, Chung, Namjin, Ghayur, Tariq, Gu, Jijie

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Identification of Anti-EGFR and Anti-ErbB3 Dual Variable Domains Immunoglobulin (DVD-Ig) Proteins with Unique Activities von Gu, Jinming, Yang, Jinsong, Chang, Qing, Liu, Zhihong, Ghayur, Tariq, Gu, Jijie

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Structure reveals function of the dual variable domain immunoglobulin (DVD-Ig™) molecule von Jakob, Clarissa G, Edalji, Rohinton, Judge, Russell A, DiGiammarino, Enrico, Li, Yingchun, Gu, Jijie, Ghayur, Tariq

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Molecular construction and optimization of anti-human IL-1α/β dual variable domain immunoglobulin (DVD-IgTM) molecules von Wu, Chengbin, Ying, Hua, Bose, Sahana, Miller, Renee, Medina, Limary, Santora, Ling, Ghayur, Tariq

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Identification of anti-ErbB2 dual variable domain immunoglobulin (DVD-Ig™) proteins with unique activities von Gu, Jinming, Yang, Jinsong, Chang, Qing, Lu, Xiaoqing, Wang, Jieyi, Chen, Mingjiu, Ghayur, Tariq, Gu, Jijie

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Substrate Specificities of Caspase Family Proteases von Talanian, R V, Quinlan, C, Trautz, S, Hackett, M C, Mankovich, J A, Banach, D, Ghayur, T, Brady, K D, Wong, W W

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Potent and conditional redirected T cell killing of tumor cells using Half DVD-Ig von Bardwell, Philip D., Staron, Matthew M., Liu, Junjian, Tao, Qingfeng, Scesney, Susanne, Bukofzer, Gail, Rodriguez, Luis E., Choi, Chee-Ho, Wang, Jennifer, Chang, Qing, Dong, Feng, Donawho, Cherrie, Wang, Jieyi, Grinnell, Christine M., Tarcsa, Edit, Hutchins, Charles, Ghayur, Tariq, Gu, Jijie

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Unusual Water-mediated Antigenic Recognition of the Proinflammatory Cytokine Interleukin-18 von Argiriadi, Maria A., Xiang, Tao, Wu, Chengbin, Ghayur, Tariq, Borhani, David W.

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Generation of Dual-Variable-Domain Immunoglobulin Molecules for Dual-Specific Targeting von Gu, Jijie, Ghayur, Tariq

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Recent advancements in DVD-Ig based therapeutic development von Dong, Feng, Ghayur, Tariq

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Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35 von Bump, N.J. (BASF Bioresearch Corporation, Worchester, MA.), Hackett, M, Hugunin, M, Seshagiri, S, Brady, K, Chen, P, Ferenz, C, Franklin, S, Ghayur, T, Li, P

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Ligand association rates to the inner-variable-domain of a dual-variable-domain immunoglobulin are significantly impacted by linker design von DiGiammarino, Enrico L., Harlan, John E., Walter, Karl A., Ladror, Uri S., Edalji, Rohinton P., Hutchins, Charles W., Lake, Marc R., Greischar, Amy J., Liu, Junjian, Ghayur, Tariq, Jakob, Clarissa G.

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Generation of Anti-apoptotic Presenilin-2 Polypeptides by Alternative Transcription, Proteolysis, and Caspase-3 Cleavage von Vito, Pasquale, Ghayur, Tariq, D'Adamio, Luciano

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Targeting dendritic cell inhibitory receptors to down regulate immune response in inflammatory disease von Wei, Hsi-Ju, Chen, Liang, Patil, Suresh, Barbon, Jeffrey, Waire, James, McCarthy, Donna, Deora, Arun, Laroux, Stephen, Jin, Liang, Tian, Yu, Veldman, Trudi, Ghayur, Tariq, Hegde, Subramanya

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Regulation of Protein Phosphatase 2A Activity by Caspase-3 during Apoptosis von Santoro, Maxine F., Annand, Robert R., Robertson, Molly M., Peng, Yun-Wen, Brady, Matthew J., Mankovich, John A., Hackett, Maria C., Ghayur, Tariq, Walter, Gernot, Wong, Winnie W., Giegel, David A.

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Proteolytic cleavage of phospholipase C–γ1 during apoptosis in Molt–4 cells von Bae, Sun Sik, Perry, David K, Oh, Yong Seok, Choi, Jang Hyun, Galadari, Sehamuddin H., Ghayur, Tariq, Ryu, Sung Ho, Hannun, Yusuf A., Suh, Pann-Ghill

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Brain uptake of multivalent and multi-specific DVD-Ig proteins after systemic administration von Karaoglu Hanzatian, Denise, Schwartz, Annette, Gizatullin, Farid, Erickson, Jamie, Deng, Kangwen, Villanueva, Ruth, Stedman, Christopher, Harris, Cristina, Ghayur, Tariq, Goodearl, Andrew

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Transmembrane TNF-dependent uptake of anti-TNF antibodies von Deora, Arun, Hegde, Subramanya, Lee, Jacqueline, Choi, Chee-Ho, Chang, Qing, Lee, Cheryl, Eaton, Lucia, Tang, Hua, Wang, Dongdong, Lee, David, Michalak, Mark, Tomlinson, Medha, Tao, Qingfeng, Gaur, Nidhi, Harvey, Bohdan, McLoughlin, Shaun, Labkovsky, Boris, Ghayur, Tariq

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