Immunoinformatics Design of Multi-Epitope Peptide-Based Vaccine Against Schistosoma mansoni Using Transmembrane Proteins as a Target von Sanches, Rodrigo C. O., Tiwari, Sandeep, Ferreira, Lais C. G., Oliveira, Flavio M., Lopes, Marcelo D., Passos, Maria J. F., Maia, Eduardo H. B., Taranto, Alex G., Kato, Rodrigo, Azevedo, Vasco A. C., Lopes, Debora O.

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Molecular Architect: A User-Friendly Workflow for Virtual Screening von Maia, Eduardo H. B, Medaglia, Lucas Rolim, da Silva, Alisson Marques, Taranto, Alex G

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Development of Potential Multi-Target Inhibitors for Human Cholinesterases and Beta-Secretase 1: A Computational Approach von Barbosa, Deyse B, do Bomfim, Mayra R, de Oliveira, Tiago A, da Silva, Alisson M, Taranto, Alex G, Cruz, Jorddy N, de Carvalho, Paulo B, Campos, Joaquín M, Santos, Cleydson B R, Leite, Franco H A

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Selectivity analyses of γ-benzylidene digoxin derivatives to different Na,K-ATPase α isoforms: a molecular docking approach von Pessôa, Marco T. C., Alves, Silmara L. G., Taranto, Alex G., Villar, José A. F. P., Blanco, Gustavo, Barbosa, Leandro A.

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Cytotoxic effects of the cardenolide convallatoxin and its Na,K-ATPase regulation von Schneider, Naira Fernanda Zanchett, Silva, Izabella Thais, Persich, Lara, de Carvalho, Annelise, Rocha, Sayonarah C., Marostica, Lucas, Ramos, Ana Carolina Pacheco, Taranto, Alex G., Pádua, Rodrigo M., Kreis, Wolfgang, Barbosa, Leandro A., Braga, Fernão C., Simões, Cláudia M. O.

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Evidence for the involvement of spinal cord-inhibitory and cytokines-modulatory mechanisms in the anti-hyperalgesic effect of hecogenin acetate, a steroidal sapogenin-acetylated, i... von Quintans, Jullyana S S, Barreto, Rosana S S, de Lucca, Jr, Waldecy, Villarreal, Cristiane F, Kaneto, Carla M, Soares, Milena B P, Branco, Alexsandro, Almeida, Jackson R G S, Taranto, Alex G, Antoniolli, Angelo R, Freitas, Rivelilson M, Quintans, Jr, Lucindo J

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Evaluation of antiplasmodial activity in silico and in vitro of N-acylhydrazone derivatives von Oliveira, Fernanda A., Pinto, Ana Claudia S., Duarte, Caique L., Taranto, Alex G., Lorenzato Junior, Eder, Cordeiro, Cleydson Finotti, Carvalho, Diogo T., Varotti, Fernando P., Fonseca, Amanda L.

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Identification of Zika Virus NS2B-NS3 Protease Inhibitors by Structure-Based Virtual Screening and Drug Repurposing Approaches von Santos, Felipe R. S, Nunes, Damiana A. F, Lima, William G, Davyt, Danilo, Santos, Luciana L, Taranto, Alex G, M. S. Ferreira, Jaqueline

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Synthesis, docking, machine learning and antiproliferative activity of the 6-ferrocene/heterocycle-2-aminopyrimidine and 5-ferrocene-1H-Pyrazole derivatives obtained by microwave-a... von Filho, Eclair Venturini, Pina, Jorge W.S., Antoniazi, Mariana K., Loureiro, Laiza B., Ribeiro, Marcos A., Pinheiro, Carlos B., Guimarães, Celina J., de Oliveira, Fátima C.E., Pessoa, Claudia, Taranto, Alex G., Greco, Sandro J.

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Production, purification and characterization of a thermostable β-1,3-glucanase produced by Moniliophthora perniciosa von Sena, Amanda R, Júnior, Gildomar L V, Góes Neto, Aristóteles, Taranto, Alex G, Pirovani, Carlos P, Cascardo, Júlio C M, Zingali, Russolina B, Bezerra, Marcos A, Assis, Sandra A

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Cytotoxic and cytostatic effects of digitoxigenin monodigitoxoside (DGX) in human lung cancer cells and its link to Na,K-ATPase von Schneider, Naira Fernanda Zanchett, Persich, Lara, Rocha, Sayonarah C., Ramos, Ana Carolina Pacheco, Cortes, Vanessa Faria, Silva, Izabella Thaís, Munkert, Jennifer, Pádua, Rodrigo M., Kreis, Wolfgang, Taranto, Alex G., Barbosa, Leandro A., Braga, Fernão C., Simões, Cláudia M.O.

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21-Benzylidene digoxin: a proapoptotic cardenolide of cancer cells that up-regulates Na,K-ATPase and epithelial tight junctions von Rocha, Sayonarah C, Pessoa, Marco T C, Neves, Luiza D R, Alves, Silmara L G, Silva, Luciana M, Santos, Herica L, Oliveira, Soraya M F, Taranto, Alex G, Comar, Moacyr, Gomes, Isabella V, Santos, Fabio V, Paixão, Natasha, Quintas, Luis E M, Noël, François, Pereira, Antonio F, Tessis, Ana C S C, Gomes, Natalia L S, Moreira, Otacilio C, Rincon-Heredia, Ruth, Varotti, Fernando P, Blanco, Gustavo, Villar, Jose A F P, Contreras, Rubén G, Barbosa, Leandro A

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Purification, characterization and structural determination of chitinases produced by Moniliophthora perniciosa von Galante, Rafaela S, Taranto, Alex G, Koblitz, Maria G B, Góes-Neto, Aristóteles, Pirovani, Carlos P, Cascardo, Júlio C M, Cruz, Sandra H, Pereira, Gonçalo A G, Assis, Sandra A de

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Cytotoxicity of AMANTADIG – a semisynthetic digitoxigenin derivative – alone and in combination with docetaxel in human hormone-refractory prostate cancer cells and its effect on N... von Silva, Izabella Thaís, Munkert, Jennifer, Nolte, Elke, Schneider, Naira Fernanda Zanchett, Rocha, Sayonarah Carvalho, Ramos, Ana Carolina Pacheco, Kreis, Wolfgang, Braga, Fernão Castro, de Pádua, Rodrigo Maia, Taranto, Alex G., Cortes, Vanessa, Barbosa, Leandro Augusto, Wach, Sven, Taubert, Helge, Simões, Cláudia Maria Oliveira

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Docking-based virtual screening of Brazilian natural compounds using the OOMT as the pharmacological target database von Carregal, Ana Paula, Maciel, Flávia V., Carregal, Juliano B., dos Reis Santos, Bianca, da Silva, Alisson Marques, Taranto, Alex G.

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Identification and Characterization of a Class Ⅲ Chitin Synthase Gene of Moniliophthora perniciosa, the Fungus That Causes Witches' Broom Disease of Cacao von Souza, Catiane S., Universidade Estadual de Feira de Santana (UEFS), Avenida Transnordestina, Feira de Santana, BA, Brazil, Oliveira, Bruno M., Universidade Estadual de Feira de Santana (UEFS), Avenida Transnordestina, Feira de Santana, BA, Brazil, Costa, Gustavo G.L., Universidade de Campinas (UNICAMP), Campinas, SP, Brazil, Schriefer, Albert, Universidade Federal da Bahia (UFBA), Hospital Universitario Professor Edgard Santos, BA, Brazil, Selbach-Schnadelbach, Alessandra, Universidade Estadual do Rio Grande do Sul (UERGS), RS, Brazil, Uetanabaro, Ana Paula T., Universidade Estadual de Feira de Santana (UEFS), Avenida Transnordestina, Feira de Santana, BA, Brazil, Pirovani, Carlos P., LGEE, Universidade Estadual de Santa Cruz (UESC), Rodovia Ilheus-Itabuna, BA, Brazil, Pereira, Goncalo A.G., Universidade de Campinas (UNICAMP), Campinas, SP, Brazil, Taranto, Alex G., Universidade Estadual de Feira de Santana (UEFS), Feira de Santana, BA, Brazil, Cascardo, Julio Cezar de M., LGEE, Universidade Estadual de Santa Cruz (UESC), Rodovia Ilheus-Itabuna, BA, Brazil, Goes-Neto, Aristoteles, Universidade Estadual de Feira de Santana (UEFS), Avenida Transnordestina, Feira de Santana, BA, Brazil

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γ-Benzylidene digoxin derivatives synthesis and molecular modeling: Evaluation of anticancer and the Na,K-ATPase activity effect von Alves, Silmara L.G., Paixão, Natasha, Ferreira, Letícia G.R., Santos, Felipe R.S., Neves, Luiza D.R., Oliveira, Gisele C., Cortes, Vanessa F., Salomé, Kahlil S., Barison, Andersson, Santos, Fabio V., Cenzi, Gisele, Varotti, Fernando P., Oliveira, Soraya M.F., Taranto, Alex G., Comar, Moacyr, Silva, Luciana M., Noël, François, Quintas, Luis Eduardo M., Barbosa, Leandro A., Villar, José A.F.P.

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Epitopes rationally selected through computational analyses induce T‐cell proliferation in mice and are recognized by serum from individuals infected with Schistosoma mansoni von Lopes, Marcelo D., Oliveira, Flávio M., Coelho, Ivan E. V., Passos, Maria J. F., Alves, Clarice C., Taranto, Alex G., Júnior, Moacyr C., Santos, Luciana L., Fonseca, Cristina T., Villar, José A. F. P., Lopes, Débora O.

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The Use of Reverse Vaccinology and Molecular Modeling Associated with Cell Proliferation Stimulation Approach to Select Promiscuous Epitopes from Schistosoma mansoni von Oliveira, Flávio M., Coelho, Ivan E. V., Lopes, Marcelo D., Taranto, Alex G., Junior, Moacyr C., Santos, Luciana L. D., Villar, José A. P. F., Fonseca, Cristina T., Lopes, Débora D. O.

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Synthesis, cytotoxic activity, and mode of action of new Santacruzamate A analogs von Andrade, Silmara N., Evangelista, Fernanda C. G., Seckler, Diego, Marques, Deisielly R., Freitas, Túlio R., Nunes, Renata R., Oliveira, Júlia T., Ribeiro, Rosy I. M. A., Santos, Hélio B., Thomé, Ralph G., Taranto, Alex G., Santos, Fabio V., Viana, Gustavo H. R., Freitas, Rossimiriam P., Humberto, Jorge L., Sabino, Adriano de P., Hilário, Flaviane F., Varotti, Fernando P.

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