Recurrent SETBP1 mutations in atypical chronic myeloid leukemia von Piazza, Rocco, Valletta, Simona, Winkelmann, Nils, Redaelli, Sara, Spinelli, Roberta, Pirola, Alessandra, Antolini, Laura, Mologni, Luca, Donadoni, Carla, Papaemmanuil, Elli, Schnittger, Susanne, Kim, Dong-Wook, Boultwood, Jacqueline, Rossi, Fabio, Gaipa, Giuseppe, De Martini, Greta P, di Celle, Paola Francia, Jang, Hyun Gyung, Fantin, Valeria, Bignell, Graham R, Magistroni, Vera, Haferlach, Torsten, Pogliani, Enrico Maria, Campbell, Peter J, Chase, Andrew J, Tapper, William J, Cross, Nicholas C P, Gambacorti-Passerini, Carlo

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Development of childhood asthma prediction models using machine learning approaches von Kothalawala, Dilini M., Murray, Clare S., Simpson, Angela, Custovic, Adnan, Tapper, William J., Arshad, S. Hasan, Holloway, John W., Rezwan, Faisal I.

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Predicting Pancreatic Cancer in the UK Biobank Cohort Using Polygenic Risk Scores and Diabetes Mellitus von Sharma, Shreya, Tapper, William J., Collins, Andrew, Hamady, Zaed Z.R.

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Clonal myelopoiesis in the UK Biobank cohort: ASXL1 mutations are strongly associated with smoking von Dawoud, Ahmed A. Z., Tapper, William J., Cross, Nicholas C. P.

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Megalencephaly syndromes: exome pipeline strategies for detecting low-level mosaic mutations von Tapper, William J, Foulds, Nicola, Cross, Nicholas C P, Aranaz, Paula, Score, Joannah, Hidalgo-Curtis, Claire, Robinson, David O, Gibson, Jane, Ennis, Sarah, Temple, I Karen, Collins, Andrew

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Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer von Couch, Fergus J, Hart, Steven N, Sharma, Priyanka, Toland, Amanda Ewart, Wang, Xianshu, Miron, Penelope, Olson, Janet E, Godwin, Andrew K, Pankratz, V Shane, Olswold, Curtis, Slettedahl, Seth, Hallberg, Emily, Guidugli, Lucia, Davila, Jaime I, Beckmann, Matthias W, Janni, Wolfgang, Rack, Brigitte, Ekici, Arif B, Slamon, Dennis J, Konstantopoulou, Irene, Fostira, Florentia, Vratimos, Athanassios, Fountzilas, George, Pelttari, Liisa M, Tapper, William J, Durcan, Lorraine, Cross, Simon S, Pilarski, Robert, Shapiro, Charles L, Klemp, Jennifer, Yao, Song, Garber, Judy, Cox, Angela, Brauch, Hiltrud, Ambrosone, Christine, Nevanlinna, Heli, Yannoukakos, Drakoulis, Slager, Susan L, Vachon, Celine M, Eccles, Diana M, Fasching, Peter A

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Clonal myelopoiesis promotes adverse outcomes in chronic kidney disease von Dawoud, Ahmed A. Z., Gilbert, Rodney D., Tapper, William J., Cross, Nicholas C. P.

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The genomic landscape and clonal evolutionary trajectory of classical hairy cell leukemia von Moreno Rueda, Luz Yurany, Bryant, Dean, Tapper, William J., Weston-Bell, Nicola J., Wedge, David C., Ansari-Pour, Naser, Sahota, Surinder S.

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Recurrent activating STAT5B N642H mutation in myeloid neoplasms with eosinophilia von Cross, Nicholas C. P., Hoade, Yvette, Tapper, William J., Carreno-Tarragona, Gonzalo, Fanelli, Tiziana, Jawhar, Mohamad, Naumann, Nicole, Pieniak, Iwo, Lübke, Johannes, Ali, Sahra, Bhuller, Kaljit, Burgstaller, Sonja, Cargo, Catherine, Cavenagh, Jamie, Duncombe, Andrew S., Das-Gupta, Emma, Evans, Paul, Forsyth, Peter, George, Philip, Grimley, Charlotte, Jack, Fergus, Munro, Laura, Mehra, Varun, Patel, Kavita, Rismani, Ali, Sciuccati, Gabriela, Thomas-Dewing, Rowena, Thornton, Patrick, Virchis, Andres, Watt, Simon, Wallis, Louise, Whiteway, Alastair, Zegocki, Kris, Bain, Barbara J., Reiter, Andreas, Chase, Andrew

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Therapeutic targeting of integrin αvβ6 in breast cancer von Moore, Kate M, Thomas, Gareth J, Duffy, Stephen W, Warwick, Jane, Gabe, Rhian, Chou, Patrick, Ellis, Ian O, Green, Andrew R, Haider, Syed, Brouilette, Kellie, Saha, Antonio, Vallath, Sabari, Bowen, Rebecca, Chelala, Claude, Eccles, Diana, Tapper, William J, Thompson, Alastair M, Quinlan, Phillip, Jordan, Lee, Gillett, Cheryl, Brentnall, Adam, Violette, Shelia, Weinreb, Paul H, Kendrew, Jane, Barry, Simon T, Hart, Ian R, Jones, J Louise, Marshall, John F

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Mapping of chromosome 1p deletions in myeloma identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as being genes in regions associated with adverse survival von Boyd, Kevin D, Ross, Fiona M, Walker, Brian A, Wardell, Christopher P, Tapper, William J, Chiecchio, Laura, Dagrada, Gianpaolo, Konn, Zoe J, Gregory, Walter M, Jackson, Graham H, Child, J Anthony, Davies, Faith E, Morgan, Gareth J

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Exome sequence read depth methods for identifying copy number changes von Kadalayil, Latha, Rafiq, Sajjad, Rose-Zerilli, Matthew J J, Pengelly, Reuben J, Parker, Helen, Oscier, David, Strefford, Jonathan C, Tapper, William J, Gibson, Jane, Ennis, Sarah, Collins, Andrew

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Genome-wide association study identifies novel susceptibility loci for KIT D816V positive mastocytosis von Galatà, Gabriella, García-Montero, Andrés C., Kristensen, Thomas, Dawoud, Ahmed A.Z., Muñoz-González, Javier I., Meggendorfer, Manja, Guglielmelli, Paola, Hoade, Yvette, Alvarez-Twose, Ivan, Gieger, Christian, Strauch, Konstantin, Ferrucci, Luigi, Tanaka, Toshiko, Bandinelli, Stefania, Schnurr, Theresia M., Haferlach, Torsten, Broesby-Olsen, Sigurd, Vestergaard, Hanne, Møller, Michael Boe, Bindslev-Jensen, Carsten, Vannucchi, Alessandro M., Orfao, Alberto, Radia, Deepti, Reiter, Andreas, Chase, Andrew J., Cross, Nicholas C.P., Tapper, William J.

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A CRISPR and high-content imaging assay compliant with ACMG/AMP guidelines for clinical variant interpretation in ciliopathies von Nazlamova, Liliya, Thomas, N. Simon, Cheung, Man-Kim, Legebeke, Jelmer, Lord, Jenny, Pengelly, Reuben J., Tapper, William J., Wheway, Gabrielle

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Linkage Disequilibrium in Human Populations von Lonjou, Christine, Zhang, Weihua, Collins, Andrew, Tapper, William J., Elahi, Eiram, Maniatis, Nikolas, Morton, Newton E.

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PRR14L mutations are associated with chromosome 22 acquired uniparental disomy, age-related clonal hematopoiesis and myeloid neoplasia von Chase, Andrew, Pellagatti, Andrea, Singh, Shalini, Score, Joannah, Tapper, William J., Lin, Feng, Hoade, Yvette, Bryant, Catherine, Trim, Nicola, Yip, Bon Ham, Zoi, Katerina, Rasi, Chiara, Forsberg, Lars A., Dumanski, Jan P., Boultwood, Jacqueline, Cross, Nicholas C. P.

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Impact of Population Structure, Effective Bottleneck Time, and Allele Frequency on Linkage Disequilibrium Maps von Zhang, Weihua, Collins, Andrew, Gibson, Jane, Tapper, William J, Hunt, Sarah, Deloukas, Panos, Bentley, David R, Morton, Newton E

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Nonlinear effects of environment on childhood asthma susceptibility von Kothalawala, Dilini M., Weiss, Veronique B. N., Kadalayil, Latha, Granell, Raquel, Curtin, John A., Murray, Clare S., Simpson, Angela, Custovic, Adnan, Tapper, William J., Rezwan, Faisal I., Arshad, Syed Hasan, Holloway, John W., Roberts, Graham C, Turner, Steve W, Haider, Sadia, Fontanella, Sara, Cullinan, Paul

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Age-related loss of chromosome Y is associated with levels of sex hormone binding globulin and clonal hematopoiesis defined by TET2 , TP53 , and CBL mutations von Dawoud, Ahmed A Z, Tapper, William J, Cross, Nicholas C P

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Integration of Genomic Risk Scores to Improve the Prediction of Childhood Asthma Diagnosis von Kothalawala, Dilini M, Kadalayil, Latha, Curtin, John A, Murray, Clare S, Simpson, Angela, Custovic, Adnan, Tapper, William J, Arshad, S Hasan, Rezwan, Faisal I, Holloway, John W, On Behalf Of Stelar/Unicorn Investigators

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