Regulatory role of PI3K‐protein kinase B on the release of interleukin‐1β in peritoneal macrophages from the ascites of cirrhotic patients von Tapia‐Abellán, A., Ruiz‐Alcaraz, A. J., Antón, G., Miras‐López, M., Francés, R., Such, J., Martínez‐Esparza, M., García‐Peñarrubia, P.

Volltext

Glycoconjugate expression on the cell wall of tps1/tps1 trehalose-deficient Candida albicans strain and implications for its interaction with macrophages von Martínez-Esparza, María, Tapia-Abellán, Ana, Vitse-Standaert, Annie, García-Peñarrubia, Pilar, Argüelles, Juan Carlos, Poulain, Daniel, Jouault, Thierry

Volltext

Regulatory role of PI3K-protein kinase B on the release of interleukin-1[beta] in peritoneal macrophages from the ascites of cirrhotic patients von Tapia-Abellan, A, Ruiz-Alcaraz, A J, Anton, G, Miras-Lopez, M, Frances, R, Such, J, Martinez-Esparza, M, Garcia-Penarrubia, P

Volltext

NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway von Hafner-Bratkovič, Iva, Sušjan, Petra, Lainšček, Duško, Tapia-Abellán, Ana, Cerović, Kosta, Kadunc, Lucija, Angosto-Bazarra, Diego, Pelegrin, Pablo, Jerala, Roman

Volltext

Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease von Cocco, Mattia, Pellegrini, Carolina, Martínez-Banaclocha, Helios, Giorgis, Marta, Marini, Elisabetta, Costale, Annalisa, Miglio, Gianluca, Fornai, Matteo, Antonioli, Luca, López-Castejón, Gloria, Tapia-Abellán, Ana, Angosto, Diego, Hafner-Bratkovič, Iva, Regazzoni, Luca, Blandizzi, Corrado, Pelegrín, Pablo, Bertinaria, Massimo

Volltext

MCC950 closes the active conformation of NLRP3 to an inactive state von Tapia-Abellán, Ana, Angosto-Bazarra, Diego, Martínez-Banaclocha, Helios, de Torre-Minguela, Carlos, Cerón-Carrasco, Jose P., Pérez-Sánchez, Horacio, Arostegui, Juan I., Pelegrin, Pablo

Volltext

Recent insights into the regulatory networks of NLRP3 inflammasome activation von Weber, Alexander N R, Bittner, Zsófia A, Shankar, Sangeetha, Liu, Xiao, Chang, Tzu-Hsuan, Jin, Tengchuan, Tapia-Abellán, Ana

Volltext

BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity von Bittner, Zsófia Agnes, Liu, Xiao, Mateo Tortola, Maria, Tapia-Abellán, Ana, Shankar, Sangeetha, Andreeva, Liudmila, Mangan, Matthew, Spalinger, Marianne, Kalbacher, Hubert, Düwell, Peter, Lovotti, Marta, Bosch, Karlotta, Dickhöfer, Sabine, Marcu, Ana, Stevanović, Stefan, Herster, Franziska, Cardona Gloria, Yamel, Chang, Tzu-Hsuan, Bork, Francesca, Greve, Carsten L, Löffler, Markus W, Wolz, Olaf-Oliver, Schilling, Nadine A, Kümmerle-Deschner, Jasmin B, Wagner, Samuel, Delor, Anita, Grimbacher, Bodo, Hantschel, Oliver, Scharl, Michael, Wu, Hao, Latz, Eicke, Weber, Alexander N R

Volltext

Pathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production von Molina-López, Cristina, Hurtado-Navarro, Laura, García, Carlos J., Angosto-Bazarra, Diego, Vallejo, Fernando, Tapia-Abellán, Ana, Marques-Soares, Joana R., Vargas, Carmen, Bujan-Rivas, Segundo, Tomás-Barberán, Francisco A., Arostegui, Juan I., Pelegrin, Pablo

Volltext

Sensing low intracellular potassium by NLRP3 results in a stable open structure that promotes inflammasome activation von Tapia-Abellán, Ana, Angosto-Bazarra, Diego, Alarcón-Vila, Cristina, Baños, María C, Hafner-Bratkovič, Iva, Oliva, Baldomero, Pelegrín, Pablo

Volltext

Isolation of functional mature peritoneal macrophages from healthy humans von Ruiz‐Alcaraz, Antonio J, Martínez‐Banaclocha, Helios, Marín‐Sánchez, Pilar, Carmona‐Martínez, Violeta, Iniesta‐Albadalejo, Miguel Angel, Tristán‐Manzano, María, Tapia‐Abellán, Ana, García‐Peñarrubia, Pilar, Machado‐Linde, Francisco, Pelegrín, Pablo, Martínez‐Esparza, María

Volltext

ASC oligomer favors caspase-1CARD domain recruitment after intracellular potassium efflux von Martín-Sánchez, Fátima, Compan, Vincent, Peñín-Franch, Alejandro, Tapia-Abellán, Ana, Gómez, Ana I, Baños-Gregori, María C, Schmidt, Florian I, Pelegrin, Pablo

Volltext

Comment on: Effective ex vivo inhibition of cryopyrin-associated periodic syndrome (CAPS)-associated mutant NLRP3 inflammasome by MCC950/CRID3: Reply von Weber, Alexander N R, Tapia-Abellán, Ana, Liu, Xiao, Aróstegui, Juan I, Pelegrín, Pablo, Welzel, Tatjana, Kuemmerle-Deschner, Jasmin B

Volltext

Effective ex vivo inhibition of cryopyrin-associated periodic syndrome (CAPS)-associated mutant NLRP3 inflammasome by MCC950/CRID3 von Weber, Alexander N R, Tapia-Abellán, Ana, Liu, Xiao, Dickhöfer, Sabine, Aróstegui, Juan I, Pelegrín, Pablo, Welzel, Tatjana, Kuemmerle-Deschner, Jasmin B

Volltext

Early endosome autoantigen 1 regulates IL-1β release upon caspase-1 activation independently of gasdermin D membrane permeabilization von Baroja-Mazo, Alberto, Compan, Vincent, Martín-Sánchez, Fátima, Tapia-Abellán, Ana, Couillin, Isabelle, Pelegrín, Pablo

Volltext

Role of MAP Kinases and PI3K-Akt on the cytokine inflammatory profile of peritoneal macrophages from the ascites of cirrhotic patients von Tapia-Abellán, Ana, Ruiz-Alcaraz, Antonio J., Hernández-Caselles, Trinidad, Such, José, Francés, Rubén, García-Peñarrubia, Pilar, Martínez-Esparza, María

Volltext

A novel CD14(high) CD16(high) subset of peritoneal macrophages from cirrhotic patients is associated to an increased response to LPS von Ruiz-Alcaraz, Antonio José, Tapia-Abellán, Ana, Fernández-Fernández, María Dolores, Tristán-Manzano, María, Hernández-Caselles, Trinidad, Sánchez-Velasco, Eduardo, Miras-López, Manuel, Martínez-Esparza, María, García-Peñarrubia, Pilar

Volltext

A novel CD14high CD16high subset of peritoneal macrophages from cirrhotic patients is associated to an increased response to LPS von Ruiz-Alcaraz, Antonio José, Tapia-Abellán, Ana, Fernández-Fernández, María Dolores, Tristán-Manzano, María, Hernández-Caselles, Trinidad, Sánchez-Velasco, Eduardo, Miras-López, Manuel, Martínez-Esparza, María, García-Peñarrubia, Pilar

Volltext

The peritoneal macrophage inflammatory profile in cirrhosis depends on the alcoholic or hepatitis C viral etiology and is related to ERK phosphorylation von Tapia-Abellán, Ana, Martínez-Esparza, María, Ruiz-Alcaraz, Antonio J, Hernández-Caselles, Trinidad, Martínez-Pascual, Cristina, Miras-López, Manuel, Such, José, Francés, Rubén, García-Peñarrubia, Pilar

Volltext

Measuring NLR Oligomerization III: Detection of NLRP3 and NLRC4 Complex by Bioluminescence Resonance Energy Transfer von Martín-Sánchez, Fátima, Peñín-Franch, Alejandro, Angosto-Bazarra, Diego, Tapia-Abellán, Ana, Compan, Vincent, Pelegrín, Pablo

Volltext