Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism von Loregger, Anke, Raaben, Matthijs, Nieuwenhuis, Joppe, Tan, Josephine M. E., Jae, Lucas T., van den Hengel, Lisa G., Hendrix, Sebastian, van den Berg, Marlene, Scheij, Saskia, Song, Ji-Ying, Huijbers, Ivo J., Kroese, Lona J., Ottenhoff, Roelof, van Weeghel, Michel, van de Sluis, Bart, Brummelkamp, Thijn, Zelcer, Noam

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Beyond the polymerase-γ theory: Production of ROS as a mode of NRTI-induced mitochondrial toxicity von Smith, Reuben L, Tan, Josephine M E, Jonker, Martijs J, Jongejan, Aldo, Buissink, Thomas, Veldhuijzen, Steve, van Kampen, Antoine H C, Brul, Stanley, van der Spek, Hans

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Differential use of E2 ubiquitin conjugating enzymes for regulated degradation of the rate-limiting enzymes HMGCR and SQLE in cholesterol biosynthesis von Tan, Josephine M.E., Cook, Emma C.L., van den Berg, Marlene, Scheij, Saskia, Zelcer, Noam, Loregger, Anke

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Control of murine brown adipocyte development by GATA6 von Jun, Seoyoung, Angueira, Anthony R, Fein, Ethan C, Tan, Josephine M E, Weller, Angela H, Cheng, Lan, Batmanov, Kirill, Ishibashi, Jeff, Sakers, Alexander P, Stine, Rachel R, Seale, Patrick

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SPRING is a Dedicated Licensing Factor for SREBP-Specific Activation by S1P von Hendrix, Sebastian, Tan, Josephine M E, Ndoj, Klevis, Kingma, Jenina, Valiloo, Masoud, Zijlstra, Lobke F, Ottenhoff, Roelof, Seidah, Nabil G, Loregger, Anke, Kober, Daniel L, Zelcer, Noam

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Beyond the polymerase-[gamma] theory: Production of ROS as a mode of NRTI-induced mitochondrial toxicity von Smith, Reuben L, Tan, Josephine M. E, Jonker, Martijs J, Jongejan, Aldo, Buissink, Thomas, Veldhuijzen, Steve, van Kampen, Antoine H. C, Brul, Stanley, van der Spek, Hans

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Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism von Loregger, Anke, Raaben, Matthijs, Nieuwenhuis, Joppe, Tan, Josephine M. E, Jae, Lucas T, Hengel, Lisa G. van den, Hendrix, Sebastian, Berg, Marlene van den, Scheij, Saskia, Song, Ji-Ying, Huijbers, Ivo J, Kroese, Lona J, Ottenhoff, Roelof, Weeghel, Michel van, Sluis, Bart van de, Brummelkamp, Thijn, Zelcer, Noam

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RAGE-Induced Cytosolic ROS Promote Mitochondrial Superoxide Generation in Diabetes von COUGHLAN, Melinda T, THORBURN, David R, BROWNLEE, Michael, BIERHAUS, Angelika, COOPER, Mark E, FORBES, Josephine M, PENFOLD, Sally A, LASKOWSKI, Adrienne, HARCOURT, Brooke E, SOURRIS, Karly C, TAN, Adeline L. Y, FUKAMI, Kei, THALLAS-BONKE, Vicki, NAWROTH, Peter P

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Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen von Lim, Hwee Ying, Lim, Sheau Yng, Tan, Chek Kun, Thiam, Chung Hwee, Goh, Chi Ching, Carbajo, Daniel, Chew, Samantha Hui Shang, See, Peter, Chakarov, Svetoslav, Wang, Xiao Nong, Lim, Li Hui, Johnson, Louise A., Lum, Josephine, Fong, Chui Yee, Bongso, Ariff, Biswas, Arijit, Goh, Chern, Evrard, Maximilien, Yeo, Kim Pin, Basu, Ranu, Wang, Jun Kit, Tan, Yingrou, Jain, Rohit, Tikoo, Shweta, Choong, Cleo, Weninger, Wolfgang, Poidinger, Michael, Stanley, Richard E., Collin, Matthew, Tan, Nguan Soon, Ng, Lai Guan, Jackson, David G., Ginhoux, Florent, Angeli, Véronique

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Processed foods drive intestinal barrier permeability and microvascular diseases von Snelson, Matthew, Tan, Sih Min, Clarke, Rachel E., de Pasquale, Cassandra, Thallas-Bonke, Vicki, Tuong-Vi Nguyen, Penfold, Sally A., Harcourt, Brooke E., Sourris, Karly C., Lindblom, Runa S., Ziemann, Mark, Steer, David, El-Osta, Assam, Davies, Michael J., Donnellan, Leigh, Deo, Permal, Kellow, Nicole J., Cooper, Mark E., Woodruff, Trent M., Mackay, Charles R., Forbes, Josephine M., Coughlan, Melinda T.

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AGE, RAGE, and ROS in Diabetic Nephropathy von Tan, Adeline L.Y., BBiomedSc, Forbes, Josephine M., PhD, Cooper, Mark E., PhD

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Disparate effects on renal and oxidative parameters following RAGE deletion, AGE accumulation inhibition, or dietary AGE control in experimental diabetic nephropathy von Tan, Adeline L Y, Sourris, Karly C, Harcourt, Brooke E, Thallas-Bonke, Vicki, Penfold, Sally, Andrikopoulos, Sofianos, Thomas, Merlin C, O'Brien, Richard C, Bierhaus, Angelika, Cooper, Mark E, Forbes, Josephine M, Coughlan, Melinda T

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Complement C5a Induces Renal Injury in Diabetic Kidney Disease by Disrupting Mitochondrial Metabolic Agility von Tan, Sih Min, Ziemann, Mark, Thallas-Bonke, Vicki, Snelson, Matthew, Kumar, Vinod, Laskowski, Adrienne, Nguyen, Tuong-Vi, Huynh, Kevin, Clarke, Michele V., Libianto, Renata, Baker, Scott T., Skene, Alison, Power, David A., MacIsaac, Richard J., Henstridge, Darren C., Wetsel, Rick A., El-Osta, Assam, Meikle, Peter J., Wilson, Scott G., Forbes, Josephine M., Cooper, Mark E., Ekinci, Elif I., Woodruff, Trent M., Coughlan, Melinda T.

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Medullary pain facilitating neurons mediate allodynia in headache-related pain von Edelmayer, Rebecca M., Vanderah, Todd W., Majuta, Lisa, Zhang, En-Tan, Fioravanti, Beatriz, De Felice, Milena, Chichorro, Juliana G., Ossipov, Michael H., King, Tamara, Lai, Josephine, Kori, Shashi H., Nelsen, Andrew C., Cannon, Keri E., Heinricher, Mary M., Porreca, Frank

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Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches von Chakarov, Svetoslav, Lim, Hwee Ying, Tan, Leonard, Lim, Sheau Yng, See, Peter, Lum, Josephine, Zhang, Xiao-Meng, Foo, Shihui, Nakamizo, Satoshi, Duan, Kaibo, Kong, Wan Ting, Gentek, Rebecca, Balachander, Akhila, Carbajo, Daniel, Bleriot, Camille, Malleret, Benoit, Tam, John Kit Chung, Baig, Sonia, Shabeer, Muhammad, Toh, Sue-Anne Ee Shiow, Schlitzer, Andreas, Larbi, Anis, Marichal, Thomas, Malissen, Bernard, Chen, Jinmiao, Poidinger, Michael, Kabashima, Kenji, Bajenoff, Marc, Ng, Lai Guan, Angeli, Veronique, Ginhoux, Florent

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Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis von Coughlan, Melinda T, Higgins, Gavin C, Nguyen, Tuong-Vi, Penfold, Sally A, Thallas-Bonke, Vicki, Tan, Sih Min, Ramm, Georg, Van Bergen, Nicole J, Henstridge, Darren C, Sourris, Karly C, Harcourt, Brooke E, Trounce, Ian A, Robb, Portia M, Laskowski, Adrienne, McGee, Sean L, Genders, Amanda J, Walder, Ken, Drew, Brian G, Gregorevic, Paul, Qian, Hongwei, Thomas, Merlin C, Jerums, George, Macisaac, Richard J, Skene, Alison, Power, David A, Ekinci, Elif I, Wijeyeratne, Xiaonan W, Gallo, Linda A, Herman-Edelstein, Michal, Ryan, Michael T, Cooper, Mark E, Thorburn, David R, Forbes, Josephine M

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AXL-initiated paracrine activation of pSTAT3 enhances mesenchymal and vasculogenic supportive features of tumor-associated macrophages von Hung, Chia-Nung, Chen, Meizhen, DeArmond, Daniel T., Chiu, Cheryl H.-L., Limboy, Catherine A., Tan, Xi, Kusi, Meena, Chou, Chih-Wei, Lin, Li-Ling, Zhang, Zhao, Wang, Chiou-Miin, Chen, Chun-Liang, Mitsuya, Kohzoh, Osmulski, Pawel A., Gaczynska, Maria E., Kirma, Nameer B., Vadlamudi, Ratna K., Gibbons, Don L., Warner, Steve, Brenner, Andrew J., Mahadevan, Daruka, Michalek, Joel E., Huang, Tim H.-M., Taverna, Josephine A.

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Deletion of bone-marrow-derived receptor for AGEs (RAGE) improves renal function in an experimental mouse model of diabetes von Tesch, Greg, Sourris, Karly C., Summers, Shaun A., McCarthy, Domenica, Ward, Micheal S., Borg, Danielle J., Gallo, Linda A., Fotheringham, Amelia K., Pettit, Allison R., Yap, Felicia Y. T., Harcourt, Brooke E., Tan, Adeline L. Y., Kausman, Joshua Y., Nikolic-Paterson, David, Kitching, Arthur R., Forbes, Josephine M.

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Cryo-EM structure of the extracellular domain of murine Thrombopoietin Receptor in complex with Thrombopoietin von Sarson-Lawrence, Kaiseal T. G., Hardy, Joshua M., Iaria, Josephine, Stockwell, Dina, Behrens, Kira, Saiyed, Tamanna, Tan, Cyrus, Jebeli, Leila, Scott, Nichollas E., Dite, Toby A., Nicola, Nicos A., Leis, Andrew P., Babon, Jeffrey J., Kershaw, Nadia J.

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Iron deficiency accelerates Helicobacter pylori-induced carcinogenesis in rodents and humans von Noto, Jennifer M, Gaddy, Jennifer A, Lee, Josephine Y, Piazuelo, M Blanca, Friedman, David B, Colvin, Daniel C, Romero-Gallo, Judith, Suarez, Giovanni, Loh, John, Slaughter, James C, Tan, Shumin, Morgan, Douglas R, Wilson, Keith T, Bravo, Luis E, Correa, Pelayo, Cover, Timothy L, Amieva, Manuel R, Peek, Jr, Richard M

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