Mitochondrial E3 ubiquitin ligase MARCHF5 controls BAK apoptotic activity independently of BH3-only proteins von Huang, Allan Shuai, Chin, Hui San, Reljic, Boris, Djajawi, Tirta M., Tan, Iris K. L., Gong, Jia-Nan, Stroud, David A., Huang, David C. S., van Delft, Mark F., Dewson, Grant

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VDAC2 enables BAX to mediate apoptosis and limit tumor development von Chin, Hui San, Li, Mark X., Tan, Iris K. L., Ninnis, Robert L., Reljic, Boris, Scicluna, Kristen, Dagley, Laura F., Sandow, Jarrod J., Kelly, Gemma L., Samson, Andre L., Chappaz, Stephane, Khaw, Seong L., Chang, Catherine, Morokoff, Andrew, Brinkmann, Kerstin, Webb, Andrew, Hockings, Colin, Hall, Cathrine M., Kueh, Andrew J., Ryan, Michael T., Kluck, Ruth M., Bouillet, Philippe, Herold, Marco J., Gray, Daniel H. D., Huang, David C. S., van Delft, Mark F., Dewson, Grant

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BAK α6 permits activation by BH3-only proteins and homooligomerization via the canonical hydrophobic groove von Li, Mark Xiang, Tan, Iris K. L., Ma, Stephen B., Hockings, Colin, Kratina, Tobias, Dengler, Michael A., Alsop, Amber E., Kluck, Ruth M., Dewson, Grant

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Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy von Bernardini, Jonathan P, Brouwer, Jason M, Tan, Iris KL, Sandow, Jarrod J, Huang, Shuai, Stafford, Che A, Bankovacki, Aleksandra, Riffkin, Christopher D, Wardak, Ahmad Z, Czabotar, Peter E, Lazarou, Michael, Dewson, Grant

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Dissociation of Bak α1 helix from the core and latch domains is required for apoptosis von Alsop, Amber E., Fennell, Stephanie C., Bartolo, Ray C., Tan, Iris K. L., Dewson, Grant, Kluck, Ruth M.

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BAK core dimers bind lipids and can be bridged by them von Cowan, Angus D., Smith, Nicholas A., Sandow, Jarrod J., Kapp, Eugene A., Rustam, Yepy H., Murphy, James M., Brouwer, Jason M., Bernardini, Jonathan P., Roy, Michael J., Wardak, Ahmad Z., Tan, Iris K., Webb, Andrew I., Gulbis, Jacqueline M., Smith, Brian J., Reid, Gavin E., Dewson, Grant, Colman, Peter M., Czabotar, Peter E.

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Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design von Brouwer, Jason M., Lan, Ping, Cowan, Angus D., Bernardini, Jonathan P., Birkinshaw, Richard W., van Delft, Mark F., Sleebs, Brad E., Robin, Adeline Y., Wardak, Ahmad, Tan, Iris K., Reljic, Boris, Lee, Erinna F., Fairlie, W. Douglas, Call, Melissa J., Smith, Brian J., Dewson, Grant, Lessene, Guillaume, Colman, Peter M., Czabotar, Peter E.

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A recombination hotspot leads to sequence variability within a novel gene (AK005651) and contributes to type 1 diabetes susceptibility von Tan, Iris K L, Mackin, Leanne, Wang, Nancy, Papenfuss, Anthony T, Elso, Colleen M, Ashton, Michelle P, Quirk, Fiona, Phipson, Belinda, Bahlo, Melanie, Speed, Terence P, Smyth, Gordon K, Morahan, Grant, Brodnicki, Thomas C

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An NZW-Derived Interval on Chromosome 7 Moderates Sialadenitis, But Not Insulitis in Congenic Nonobese Diabetic Mice von Burt, Rachel A, Watkins, Laura, Tan, Iris K. L, Wang, Nancy, Quirk, Fiona, Mackin, Leanne, Morgan, Phillip, Zhang, Jian-Guo, Berzins, Stuart P, Morahan, Grant, Brodnicki, Thomas C

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Dynamic reconfiguration of pro‐apoptotic BAK on membranes von Sandow, Jarrod J, Tan, Iris KL, Huang, Alan S, Masaldan, Shashank, Bernardini, Jonathan P, Wardak, Ahmad Z, Birkinshaw, Richard W, Ninnis, Robert L, Liu, Ziyan, Dalseno, Destiny, Lio, Daisy, Infusini, Giuseppi, Czabotar, Peter E, Webb, Andrew I, Dewson, Grant

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Dissociation of Bak [alpha]1 helix from the core and latch domains is required for apoptosis von Alsop, Amber E, Fennell, Stephanie C, Bartolo, Ray C, Tan, Iris K L, Dewson, Grant, Kluck, Ruth M

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Effects of Horticultural Therapy on Asian Older Adults: A Randomized Controlled Trial von Ng, Kheng Siang Ted, Sia, Angelia, Ng, Maxel K W, Tan, Crystal T Y, Chan, Hui Yu, Tan, Chay Hoon, Rawtaer, Iris, Feng, Lei, Mahendran, Rathi, Larbi, Anis, Kua, Ee Heok, Ho, Roger C M

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TRIDENT-2: National Implementation of Genome-wide Non-invasive Prenatal Testing as a First-Tier Screening Test in the Netherlands von van der Meij, Karuna R.M., Sistermans, Erik A., Macville, Merryn V.E., Stevens, Servi J.C., Bax, Caroline J., Bekker, Mireille N., Bilardo, Caterina M., Boon, Elles M.J., Boter, Marjan, Diderich, Karin E.M., de Die-Smulders, Christine E.M., Duin, Leonie K., Faas, Brigitte H.W., Feenstra, Ilse, Haak, Monique C., Hoffer, Mariëtte J.V., den Hollander, Nicolette S., Hollink, Iris H.I.M., Jehee, Fernanda S., Knapen, Maarten F.C.M., Kooper, Angelique J.A., van Langen, Irene M., Lichtenbelt, Klaske D., Linskens, Ingeborg H., van Maarle, Merel C., Oepkes, Dick, Pieters, Mijntje J., Schuring-Blom, G. Heleen, Sikkel, Esther, Sikkema-Raddatz, Birgit, Smeets, Dominique F.C.M., Srebniak, Malgorzata I., Suijkerbuijk, Ron F., Tan-Sindhunata, Gita M., van der Ven, A. Jeanine E.M., van Zelderen-Bhola, Shama L., Henneman, Lidewij, Galjaard, Robert-Jan H., Van Opstal, Diane, Weiss, Marjan M.

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Biological Sex Modulates the Adrenal and Blood Pressure Responses to Angiotensin II von Shukri, Mohammad Zaki, Tan, Jia Wei, Manosroi, Worapaka, Pojoga, Luminita H, Rivera, Alicia, Williams, Jonathan S, Seely, Ellen W, Adler, Gail K, Jaffe, Iris Z, Karas, Richard H, Williams, Gordon H, Romero, Jose R

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TSC1/2 mutations define a molecular subset of HCC with aggressive behaviour and treatment implication von Ho, Daniel W H, Chan, Lo K, Chiu, Yung T, Xu, Iris M J, Poon, Ronnie T P, Cheung, Tan T, Tang, Chung N, Tang, Victor W L, Lo, Irene L O, Lam, Polly W Y, Yau, Derek T W, Li, Miao X, Wong, Chun M, Ng, Irene O L

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Current controversies in TNM for the radiological staging of rectal cancer and how to deal with them: results of a global online survey and multidisciplinary expert consensus von Lambregts, Doenja M. J., Bogveradze, Nino, Blomqvist, Lennart K., Fokas, Emmanouil, Garcia-Aguilar, Julio, Glimelius, Bengt, Gollub, Marc J., Konishi, Tsuyoshi, Marijnen, Corrie A. M., Nagtegaal, Iris D., Nilsson, Per J., Perez, Rodrigo O., Snaebjornsson, Petur, Taylor, Stuart A., Tolan, Damian J. M., Valentini, Vincenzo, West, Nicholas P., Wolthuis, Albert, Lahaye, Max J., Maas, Monique, Beets, Geerard L., Beets-Tan, Regina G.H.

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Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer’s disease von Broce, Iris J., Tan, Chin Hong, Fan, Chun Chieh, Jansen, Iris, Savage, Jeanne E., Witoelar, Aree, Wen, Natalie, Hess, Christopher P., Dillon, William P., Glastonbury, Christine M., Glymour, Maria, Yokoyama, Jennifer S., Elahi, Fanny M., Rabinovici, Gil D., Miller, Bruce L., Mormino, Elizabeth C., Sperling, Reisa A., Bennett, David A., McEvoy, Linda K., Brewer, James B., Feldman, Howard H., Hyman, Bradley T., Pericak-Vance, Margaret, Haines, Jonathan L., Farrer, Lindsay A., Mayeux, Richard, Schellenberg, Gerard D., Yaffe, Kristine, Sugrue, Leo P., Dale, Anders M., Posthuma, Danielle, Andreassen, Ole A., Karch, Celeste M., Desikan, Rahul S.

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Xist nucleates local protein gradients to propagate silencing across the X chromosome von Markaki, Yolanda, Gan Chong, Johnny, Wang, Yuying, Jacobson, Elsie C., Luong, Christy, Tan, Shawn Y.X., Jachowicz, Joanna W., Strehle, Mackenzie, Maestrini, Davide, Banerjee, Abhik K., Mistry, Bhaven A., Dror, Iris, Dossin, Francois, Schöneberg, Johannes, Heard, Edith, Guttman, Mitchell, Chou, Tom, Plath, Kathrin

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Definition of the Rectum: An International, Expert-based Delphi Consensus von DʼSouza, Nigel, de Neree tot Babberich, Michael P M, d’Hoore, Andre, Tiret, Emmanuel, Xynos, Evaghelos, Beets-Tan, Regina G H, Nagtegaal, Iris D, Blomqvist, Lennart, Holm, Torbjorn, Glimelius, Bengt, Lacy, Antonio, Cervantes, Andres, Glynne-Jones, Robert, West, Nicholas P, Perez, Rodrigo O, Quadros, Claudio, Lee, Kil Yeon, Madiba, Thandinkosi E, Wexner, Steven D, Garcia-Aguilar, Julio, Sahani, Dushyant, Moran, Brendan, Tekkis, Paris, Rutten, Harm J, Tanis, Pieter J, Wiggers, Theo, Brown, Gina

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Gastrointestinal tissue‐based molecular biomarkers: a practical categorisation based on the 2019 World Health Organization classification of epithelial digestive tumours von Quezada‐Marín, Javier I, Lam, Alfred K, Ochiai, Atsushi, Odze, Robert D, Washington, Kay M, Fukayama, Masashi, Rugge, Massimo, Klimstra, David S, Nagtegaal, Iris D, Tan, Puay‐Hoon, Arends, Mark J, Goldblum, John R, Cree, Ian A, Salto‐Tellez, Manuel

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