Preclinical Characterisation of JNJ-54257099 – A Potent Uridine-Based Nucleotide Polymerase Inhibitor in Phase I Clinical Development for the Treatment of Chronic Hepatitis C von Tambuyzer, L, Vijgen, L, Jonckers, T.H, Lachau-Durand, S, Snoeys, J, Leclercq, L, Berke, J.M, Deval, J, Van Remoortere, P, Simmen, K, De Meyer, S, Raboisson, P

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Etravirine in treatment‐experienced, HIV‐1‐infected children and adolescents: 48‐week safety, efficacy and resistance analysis of the phase II PIANO study von Tudor‐Williams, G, Cahn, P, Chokephaibulkit, K, Fourie, J, Karatzios, C, Dincq, S, Opsomer, M, Kakuda, TN, Nijs, S, Tambuyzer, L, Tomaka, FL

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P221 VIROLOGY ANALYSES OF SIMEPREVIR IN PHASE 2B AND 3 STUDIES von Lenz, O, Verbinnen, T, Fevery, B, Tambuyzer, L, Vijgen, L, Peeters, M, Buelens, A, Beumont-Mauviel, M, Picchio, G, de Meyer, S

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Efficacy of etravirine combined with darunavir or other ritonavir‐boosted protease inhibitors in HIV‐1‐infected patients: an observational study using pooled European cohort data... von Vingerhoets, J, Calvez, V, Flandre, P, Marcelin, A‐G, Ceccherini‐Silberstein, F, Perno, C‐F, Mercedes Santoro, M, Bateson, R, Nelson, M, Cozzi‐Lepri, A, Grarup, J, Lundgren, J, Incardona, F, Kaiser, R, Sonnerborg, A, Clotet, B, Paredes, R, Günthard, HF, Ledergerber, B, Hoogstoel, A, Nijs, S, Tambuyzer, L, Lavreys, L, Opsomer, M

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Resistance profile of etravirine: combined analysis of baseline genotypic and phenotypic data from the randomized, controlled Phase III clinical studies von VINGERHOETS, Johan, TAMBUYZER, Lotke, AZIJN, Hilde, HOOGSTOEL, Annemie, NIJS, Steven, PEETERS, Monika, DE BETHUNE, Marie-Pierre, DE SMEDT, Goedele, WOODFALL, Brian, PICCHIO, Gastón

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Compilation and prevalence of mutations associated with resistance to non-nucleoside reverse transcriptase inhibitors von TAMBUYZER, Lotke, AZIJN, Hilde, RIMSKY, Laurence T, VINGERHOETS, Johan, LECOCQ, Pierre, KRAUS, Guenter, PICCHIO, Gaston, DE BETHUNE, Marie-Pierre

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THU-261 - Preclinical Characterisation of JNJ-54257099 – A Potent Uridine-Based Nucleotide Polymerase Inhibitor in Phase I Clinical Development for the Treatment of Chronic Hepatit... von Tambuyzer, L., Vijgen, L., Jonckers, T.H., Lachau-Durand, S., Snoeys, J., Leclercq, L., Berke, J.M., Deval, J., Van Remoortere, P., Simmen, K., De Meyer, S., Raboisson, P.

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Sensitive testing of plasma HIV-1 RNA and Sanger sequencing of cellular HIV-1 DNA for the detection of drug resistance prior to starting first-line antiretroviral therapy with etra... von Geretti, Anna Maria, Conibear, Tim, Hill, Andrew, Johnson, Jeffrey A., Tambuyzer, Lotke, Thys, Kim, Vingerhoets, Johan, Van Delft, Yvon

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Short Communication Prevalence of Susceptibility to Etravirine by Genotype and Phenotype in Samples Received for Routine HIV Type 1 Resistance Testing in the United States von PICCHIO, Gaston, VINGERHOETS, Johan, TAMBUYZER, Lotke, COAKLEY, Eoin, HADDAD, Mojgan, WITEK, James

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Similar predictions of etravirine sensitivity regardless of genotypic testing method used: comparison of available scoring systems von VINGERHOETS, Johan, NIJS, Steven, TAMBUYZER, Lotke, HOOGSTOEL, Annemie, ANDERSON, David, PICCHIO, Gaston

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Etravirine limits the emergence of darunavir and other protease inhibitor resistance-associated mutations in the DUET trials von PEETERS, Monika, VINGERHOETS, Johan, TAMBUYZER, Lotke, AZIJN, Hilde, HILL, Andrew, DE MEYER, Sandra, PICCHIO, Gaston

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Resistance analyses in highly treatment-experienced patients treated with etravirine in a roll-over study confirm the results from the Phase III DUET studies von Tambuyzer, L, Hoogstoel, A, Nijs, S, Tomaka, F, De Meyer, S, Vingerhoets, J

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Efficacy of etravirine combined with darunavir or other ritonavir‐boosted protease inhibitors in HIV ‐1‐infected patients: an observational study using pooled E uropean cohort data... von Vingerhoets, J, Calvez, V, Flandre, P, Marcelin, A‐G, Ceccherini‐Silberstein, F, Perno, C‐F, Mercedes Santoro, M, Bateson, R, Nelson, M, Cozzi‐Lepri, A, Grarup, J, Lundgren, J, Incardona, F, Kaiser, R, Sonnerborg, A, Clotet, B, Paredes, R, Günthard, HF, Ledergerber, B, Hoogstoel, A, Nijs, S, Tambuyzer, L, Lavreys, L, Opsomer, M

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Short communication: activity of etravirine on different HIV type 1 subtypes: in vitro susceptibility in treatment-naive patients and week 48 pooled DUET study data von Vingerhoets, Johan, Azijn, Hilde, Tambuyzer, Lotke, Dierynck, Inge, De Meyer, Sandra, Rimsky, Laurence, Nijs, Steven, De Smedt, Goedele, de Béthune, Marie-Pierre, Picchio, Gaston

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Etravirine protects the activity of darunavir in the DUET trials von Peeters, M, Vingerhoets, J, Tambuyzer, L, Azijn, H, Hill, AM, De Meyer, S, Picchio, G

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Activity of etravirine on different HIV-1 subtypes: week 48 data of the pooled DUET trials and in vitro susceptibility in treatment-naïve patients von Vingerhoets, J, Azijn, H, Tambuyzer, L, Dierynck, I, De Meyer, S, Rimsky, L, Peeters, M, De Smedt, G, de Béthune, MP, Picchio, G

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Decline and incomplete recovery in cancer diagnoses during the COVID-19 pandemic in Belgium: a year-long, population-level analysis von Peacock, H.M., Tambuyzer, T., Verdoodt, F., Calay, F., Poirel, H.A., De Schutter, H., Francart, J., Van Damme, N., Van Eycken, L.

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Enteric and serological distribution of serotonin and its precursor tryptophan in perinatal low and normal weight piglets von Willemen, S. A., Che, L., Dewilde, S., Van Hauwaert, M. L., De Vos, M., Huygelen, V., Fransen, E., Tambuyzer, B. R., Casteleyn, C., Van Cruchten, S., Van Ginneken, C.

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The need for worldwide policy and action plans for rare diseases von Forman, John, Taruscio, Domenica, Llera, Virginia A., Barrera, Luis A., Coté, Timothy R., Edfjäll, Catarina, Gavhed, Désirée, Haffner, Marlene E., Nishimura, Yukiko, Posada, Manuel, Tambuyzer, Erik, Groft, Stephen C., Henter, Jan-Inge

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Electrical stimulation of the bed nucleus of the stria terminalis reduces anxiety in a rat model von Luyck, K, Tambuyzer, T, Deprez, M, Rangarajan, J, Nuttin, B, Luyten, L

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