IgE+ memory B cells and plasma cells generated through a germinal-center pathway von Talay, Oezcan, Yan, Donghong, Brightbill, Hans D, Straney, Elizabeth E M, Zhou, Meijuan, Ladi, Ena, Lee, Wyne P, Egen, Jackson G, Austin, Cary D, Xu, Min, Wu, Lawren C

Volltext

B7-H1 (PD-L1) on T cells is required for T-cell-mediated conditioning of dendritic cell maturation von Talay, Oezcan, Shen, Ching-Hung, Chen, Lieping, Chen, Jianzhu

Volltext

Antigen-bearing dendritic cells regulate the diverse pattern of memory CD8 T-cell development in different tissues von Shen, Ching-Hung, Talay, Oezcan, Mahajan, Vinay S., Leskov, Ilya B., Eisen, Herman N., Chen, Jianzhu

Volltext

Tumors establish resistance to immunotherapy by regulating Treg recruitment via CCR4 von Marshall, Lisa A, Marubayashi, Sachie, Jorapur, Aparna, Jacobson, Scott, Zibinsky, Mikhail, Robles, Omar, Hu, Dennis Xiaozhou, Jackson, Jeffrey J, Pookot, Deepa, Sanchez, Jerick, Brovarney, Martin, Wadsworth, Angela, Chian, David, Wustrow, David, Kassner, Paul D, Cutler, Gene, Wong, Brian, Brockstedt, Dirk G, Talay, Oezcan

Volltext

Tumors establish resistance to immunotherapy by regulating T reg recruitment via CCR4 von Marshall, Lisa A, Marubayashi, Sachie, Jorapur, Aparna, Jacobson, Scott, Zibinsky, Mikhail, Robles, Omar, Hu, Dennis Xiaozhou, Jackson, Jeffrey J, Pookot, Deepa, Sanchez, Jerick, Brovarney, Martin, Wadsworth, Angela, Chian, David, Wustrow, David, Kassner, Paul D, Cutler, Gene, Wong, Brian, Brockstedt, Dirk G, Talay, Oezcan

Volltext

CCR4 Antagonists Inhibit T reg Trafficking into the Tumor Microenvironment von Ketcham, John M, Marshall, Lisa A, Talay, Oezcan

Volltext

EBV.sup.+ tumors exploit tumor cell-intrinsic and -extrinsic mechanisms to produce regulatory T cell-recruiting chemokines CCL17 and CCL22 von Jorapur, Aparna, Marshall, Lisa A, Jacobson, Scott, Xu, Mengshu, Marubayashi, Sachie, Zibinsky, Mikhail, Hu, Dennis X, Robles, Omar, Jackson, Jeffrey J, Baloche, Valentin, Busson, Pierre, Wustrow, David, Brockstedt, Dirk G, Talay, Oezcan, Kassner, Paul D, Cutler, Gene

Volltext

Novel Piperidinyl-Azetidines as Potent and Selective CCR4 Antagonists Elicit Antitumor Response as a Single Agent and in Combination with Checkpoint Inhibitors von Robles, Omar, Jackson, Jeffrey J, Marshall, Lisa, Talay, Oezcan, Chian, David, Cutler, Gene, Diokno, Raymond, Hu, Dennis X, Jacobson, Scott, Karbarz, Emily, Kassner, Paul D, Ketcham, John M, McKinnell, Jenny, Meleza, Cesar, Reilly, Maureen K, Riegler, Erin, Shunatona, Hunter P, Wadsworth, Angela, Younai, Ashkaan, Brockstedt, Dirk G, Wustrow, David J, Zibinsky, Mikhail

Volltext

CCR4 Antagonists Inhibit Treg Trafficking into the Tumor Microenvironment von Ketcham, John M, Marshall, Lisa A, Talay, Oezcan

Volltext

EBV+ tumors exploit tumor cell-intrinsic and -extrinsic mechanisms to produce regulatory T cell-recruiting chemokines CCL17 and CCL22 von Jorapur, Aparna, Marshall, Lisa A, Jacobson, Scott, Xu, Mengshu, Marubayashi, Sachie, Zibinsky, Mikhail, Hu, Dennis X, Robles, Omar, Jackson, Jeffrey J, Baloche, Valentin, Busson, Pierre, Wustrow, David, Brockstedt, Dirk G, Talay, Oezcan, Kassner, Paul D, Cutler, Gene

Volltext

Discovery of a Potent and Selective CCR4 Antagonist That Inhibits T reg Trafficking into the Tumor Microenvironment von Jackson, Jeffrey J, Ketcham, John M, Younai, Ashkaan, Abraham, Betty, Biannic, Berenger, Beck, Hilary P, Bui, Minna H T, Chian, David, Cutler, Gene, Diokno, Raymond, Hu, Dennis X, Jacobson, Scott, Karbarz, Emily, Kassner, Paul D, Marshall, Lisa, McKinnell, Jenny, Meleza, Cesar, Okal, Abood, Pookot, Deepa, Reilly, Maureen K, Robles, Omar, Shunatona, Hunter P, Talay, Oezcan, Walker, James R, Wadsworth, Angela, Wustrow, David J, Zibinsky, Mikhail

Volltext

Discovery of a Potent and Selective CCR4 Antagonist That Inhibits Treg Trafficking into the Tumor Microenvironment von Jackson, Jeffrey J, Ketcham, John M, Younai, Ashkaan, Abraham, Betty, Biannic, Berenger, Beck, Hilary P, Bui, Minna H. T, Chian, David, Cutler, Gene, Diokno, Raymond, Hu, Dennis X, Jacobson, Scott, Karbarz, Emily, Kassner, Paul D, Marshall, Lisa, McKinnell, Jenny, Meleza, Cesar, Okal, Abood, Pookot, Deepa, Reilly, Maureen K, Robles, Omar, Shunatona, Hunter P, Talay, Oezcan, Walker, James R, Wadsworth, Angela, Wustrow, David J, Zibinsky, Mikhail

Volltext

Abstract 4752: EBV associated tumors have increased regulatory T cell recruitment and are therefore a potential indication for treatment with potent and selective small molecule CC... von Talay, Oezcan, Jorapur, Aparna, Jacobson, Scott, Marubayashi, Sachie, Marshall, Lisa, Suthram, Silpa, Robles, Omar, Ketcham, John, Reilly, Maureen K., Younai, Ashkaan, Biannic, Berenger, Hu, Dennis, Bui, Minna, Schwarz, Jacob, Kassner, Paul, Cutler, Gene

Volltext

Abstract 1104: Targeting the stress response kinase GCN2 to restore immunity in the tumor microenvironment von Ravishankar, Buvana, Adusumilli, Lavanya, Pookot, Deepa Pookot, Huang, Emily, Sreenivasan, Raashi, Marshall, Lisa, Kaveri, Deepika, Talay, Oezcan, Suthram, Silpa, Miakicheva, Svetlana, Okal, Abood, Zibinsky, Mikhail, Jackson, Jeffrey, Shibuya, Grant, Leger, Paul, Tivitmahaisoon, Parcharee, Jacobson, Scott, Wong, Steve, Wadsworth, Angela, Sanchez, Jerick, Brovarney, Martin, Chian, David, Marubayashi, Sachie, Jorapur, Aparna, Bradford, Delia, Colas, Christophe, Cutler, Gene, Schwartz, Jacob, Wustrow, David, Kassner, Paul, Brockstedt, Dirk

Volltext

Abstract 4441: Discovery of potent and selective inhibitors of USP7 with anti-tumor activity in vitro and in vivo von Ohol, Yamini M., Sun, Michael, Leger, Paul, Hu, Dennis, Biannic, Berenger, Rana, Payal, Cho, Cynthia, Jacobson, Scott, Wong, Steve, Sanchez, Jerick, Han, Xinping, Young, Kyle, Okano, Akinori, Maung, Jack, Cutler, Gene, Shah, Nick, Adusumilli, Lavanya, Kaveri, Deepika, Talay, Oezcan, Pookot, Deepa, Abraham, Betty, Bradford, Delia, Kozon, Nathan, Colas, Christophe, Kim, Andrea, Schwarz, Jacob, Wustrow, David, Brockstedt, Dirk, Kassner, Paul

Volltext

FLX193: A Potent, Selective CCR4 Antagonist for Allergic Disorders von Jorapur, Aparna, Marshall, Lisa, Bradford, Delia, Brovarney, Martin, Chian, David, Wadsworth, Angela, Sanchez, Jerick, Jacobson, Scott, Karbarz, Emily, Robles, Omar, Younai, Ashkaan, Ketcham, John, Ng, Andrew, Tivitmahaisoon, Parcharee, Pookot, Deepa, Marubayashi, Sachie, Kozon, Nathan, Colas, Christophe, Okal, Abood, Cutler, Gene, Wustrow, David, Schwarz, Jacob, Talay, Oezcan, Brockstedt, Dirk, Wong, Brian

Volltext

Abstract 4600: Potent and selective C-C chemokine receptor (CCR4) antagonists potentiate anti-tumor immune responses by inhibiting regulatory T cells (Treg) von Talay, Oezcan, Marshall, Lisa, Meleza, Cesar, Reilly, Maureen K., Robles, Omar, Zibisky, Mikhail, Okal, Abood, Seitz, Lisa, McKinnell, Jenny, Jacobson, Scott, Riegler, Erin, Karbaz, Emily, Chian, David, Wadsworth, Angela, Kassner, Paul, Wustrow, David, Fridman, Jordan S.

Volltext

Abstract 2915: Discovery and optimization of potent and selective inhibitors of USP7 to enhance anti-tumor immunity and target tumor growth von Abraham, Betty, Adusumilli, Lavanya, Biannic, Berenger, Bradford, Delia, Brovarney, Martin, Chian, David, Cutler, Gene, Han, Xinping, Hu, Dennis, Jacobson, Scott, Johnson, Sherra, Kassner, Paul, Kaveri, Deepika, Ketcham, John, Kim, Andrea, Leger, Paul, Marshall, Lisa, Marubayashi, Sachie, Maung, Jack, McKinnell, Jenny, Meleza, Cesar, Ohol, Yamini, Okano, Akinori, Peiser, Leanne, Pookot, Deepa, Rana, Payal, Schwarz, Jacob, Shah, Nick, Shibuya, Grant, Sun, Michael, Suthram, Silpa, Talay, Oezcan, Wadsworth, Angela, Wustrow, David, Young, Kyle, Napper, Andrew

Volltext

IgE+ memory B cells and plasma cells generated through a germinal-center pathway von Talay, Oezcan, Yan, Donghong, Brightbill, Hans D, Straney, Elizabeth E M, Zhou, Meijuan, Ladi, Ena, Lee, Wyne P, Egen, Jackson G, Austin, Cary D, Xu, Min, Wu, Lawren C

Volltext

Addendum: [IgE.sup.+] memory B cells and plasma cells generated through a germinal-center pathway von Talay, Oezcan, Yan, Donghong, Brightbill, Hans D, Straney, Elizabeth E.M, Zhou, Meijuan, Ladi, Ena, Lee, Wyne P, Egen, Jackson G, Austin, Cary D, Xu, Min, Wu, Lawren C

Volltext