Validation of a Plasma-Based Comprehensive Cancer Genotyping Assay Utilizing Orthogonal Tissue- and Plasma-Based Methodologies von Odegaard, Justin I, Vincent, John J, Mortimer, Stefanie, Vowles, James V, Ulrich, Bryan C, Banks, Kimberly C, Fairclough, Stephen R, Zill, Oliver A, Sikora, Marcin, Mokhtari, Reza, Abdueva, Diana, Nagy, Rebecca J, Lee, Christine E, Kiedrowski, Lesli A, Paweletz, Cloud P, Eltoukhy, Helmy, Lanman, Richard B, Chudova, Darya I, Talasaz, AmirAli

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The Landscape of Actionable Genomic Alterations in Cell-Free Circulating Tumor DNA from 21,807 Advanced Cancer Patients von Zill, Oliver A, Banks, Kimberly C, Fairclough, Stephen R, Mortimer, Stefanie A, Vowles, James V, Mokhtari, Reza, Gandara, David R, Mack, Philip C, Odegaard, Justin I, Nagy, Rebecca J, Baca, Arthur M, Eltoukhy, Helmy, Chudova, Darya I, Lanman, Richard B, Talasaz, AmirAli

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mRNA-Seq of single prostate cancer circulating tumor cells reveals recapitulation of gene expression and pathways found in prostate cancer von Cann, Gordon M, Gulzar, Zulfiqar G, Cooper, Samantha, Li, Robin, Luo, Shujun, Tat, Mai, Stuart, Sarah, Schroth, Gary, Srinivas, Sandhya, Ronaghi, Mostafa, Brooks, James D, Talasaz, Amirali H

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Comprehensive molecular characterization of clinical responses to PD-1 inhibition in metastatic gastric cancer von Kim, Seung Tae, Cristescu, Razvan, Bass, Adam J., Kim, Kyoung-Mee, Odegaard, Justin I., Kim, Kyung, Liu, Xiao Qiao, Sher, Xinwei, Jung, Hun, Lee, Mijin, Lee, Sujin, Park, Se Hoon, Park, Joon Oh, Park, Young Suk, Lim, Ho Yeong, Lee, Hyuk, Choi, Mingew, Talasaz, AmirAli, Kang, Peter Soonmo, Cheng, Jonathan, Loboda, Andrey, Lee, Jeeyun, Kang, Won Ki

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Genomic Alterations in Circulating Tumor DNA from Diverse Cancer Patients Identified by Next-Generation Sequencing von Schwaederle, Maria, Chattopadhyay, Ranajoy, Kato, Shumei, Fanta, Paul T, Banks, Kimberly C, Choi, In Sil, Piccioni, David E, Ikeda, Sadakatsu, Talasaz, AmirAli, Lanman, Richard B, Bazhenova, Lyudmila, Kurzrock, Razelle

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Utility of Genomic Assessment of Blood-Derived Circulating Tumor DNA (ctDNA) in Patients with Advanced Lung Adenocarcinoma von Schwaederlé, Maria C, Patel, Sandip P, Husain, Hatim, Ikeda, Megumi, Lanman, Richard B, Banks, Kimberly C, Talasaz, AmirAli, Bazhenova, Lyudmila, Kurzrock, Razelle

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Spectrum of driver mutations and clinical impact of circulating tumor DNA analysis in non–small cell lung cancer: Analysis of over 8000 cases von Mack, Philip C., Banks, Kimberly C., Espenschied, Carin R., Burich, Rebekah A., Zill, Oliver A., Lee, Christine E., Riess, Jonathan W., Mortimer, Stefanie A., Talasaz, AmirAli, Lanman, Richard B., Gandara, David R.

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Single cell profiling of circulating tumor cells: transcriptional heterogeneity and diversity from breast cancer cell lines von Powell, Ashley A, Talasaz, Amirali H, Zhang, Haiyu, Coram, Marc A, Reddy, Anupama, Deng, Glenn, Telli, Melinda L, Advani, Ranjana H, Carlson, Robert W, Mollick, Joseph A, Sheth, Shruti, Kurian, Allison W, Ford, James M, Stockdale, Frank E, Quake, Stephen R, Pease, R Fabian, Mindrinos, Michael N, Bhanot, Gyan, Dairkee, Shanaz H, Davis, Ronald W, Jeffrey, Stefanie S

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Validation of Microsatellite Instability Detection Using a Comprehensive Plasma-Based Genotyping Panel von Willis, Jason, Lefterova, Martina I, Artyomenko, Alexander, Kasi, Pashtoon Murtaza, Nakamura, Yoshiaki, Mody, Kabir, Catenacci, Daniel V T, Fakih, Marwan, Barbacioru, Catalin, Zhao, Jing, Sikora, Marcin, Fairclough, Stephen R, Lee, Hyuk, Kim, Kyoung-Mee, Kim, Seung Tae, Kim, Jinchul, Gavino, Danielle, Benavides, Manuel, Peled, Nir, Nguyen, Timmy, Cusnir, Mike, Eskander, Ramez N, Azzi, Georges, Yoshino, Takayuki, Banks, Kimberly C, Raymond, Victoria M, Lanman, Richard B, Chudova, Darya I, Talasaz, AmirAli, Kopetz, Scott, Lee, Jeeyun, Odegaard, Justin I

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Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA von Lanman, Richard B, Mortimer, Stefanie A, Zill, Oliver A, Sebisanovic, Dragan, Lopez, Rene, Blau, Sibel, Collisson, Eric A, Divers, Stephen G, Hoon, Dave S B, Kopetz, E Scott, Lee, Jeeyun, Nikolinakos, Petros G, Baca, Arthur M, Kermani, Bahram G, Eltoukhy, Helmy, Talasaz, AmirAli

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Isolating highly enriched populations of circulating epithelial cells and other rare cells from blood using a magnetic sweeper device von Talasaz, AmirAli H, Powell, Ashley A, Huber, David E, Berbee, James G, Roh, Kyung-Ho, Yu, Wong, Xiao, Wenzhong, Davis, Mark M, Pease, R. Fabian, Mindrinos, Michael N, Jeffrey, Stefanie S, Davis, Ronald W

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Next‐Generation Sequencing of Circulating Tumor DNA Reveals Frequent Alterations in Advanced Hepatocellular Carcinoma von Ikeda, Sadakatsu, Tsigelny, Igor F., Skjevik, Åge A., Kono, Yuko, Mendler, Michel, Kuo, Alexander, Sicklick, Jason K., Heestand, Gregory, Banks, Kimberly C., Talasaz, AmirAli, Lanman, Richard B., Lippman, Scott, Kurzrock, Razelle

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Cell-Free DNA Next-Generation Sequencing in Pancreatobiliary Carcinomas von Zill, Oliver A, Greene, Claire, Sebisanovic, Dragan, Siew, Lai Mun, Leng, Jim, Vu, Mary, Hendifar, Andrew E, Wang, Zhen, Atreya, Chloe E, Kelley, Robin K, Van Loon, Katherine, Ko, Andrew H, Tempero, Margaret A, Bivona, Trever G, Munster, Pamela N, Talasaz, AmirAli, Collisson, Eric A

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Detection rate of actionable mutations in diverse cancers using a biopsy-free (blood) circulating tumor cell DNA assay von Schwaederle, Maria, Husain, Hatim, Fanta, Paul T, Piccioni, David E, Kesari, Santosh, Schwab, Richard B, Banks, Kimberly C, Lanman, Richard B, Talasaz, AmirAli, Parker, Barbara A, Kurzrock, Razelle

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Molecular Profiling of Hepatocellular Carcinoma Using Circulating Cell-Free DNA von Kaseb, Ahmed O, Sánchez, Nora S, Sen, Shiraj, Kelley, Robin K, Tan, Benjamin, Bocobo, Andrea G, Lim, Kian H, Abdel-Wahab, Reham, Uemura, Marc, Pestana, Roberto Carmagnani, Qiao, Wei, Xiao, Lianchun, Morris, Jeffrey, Amin, Hesham M, Hassan, Manal M, Rashid, Asif, Banks, Kimberly C, Lanman, Richard B, Talasaz, AmirAli, Mills-Shaw, Kenna R, George, Bhawana, Haque, Abedul, Raghav, Kanwal P S, Wolff, Robert A, Yao, James C, Meric-Bernstam, Funda, Ikeda, Sadakatsu, Kurzrock, Razelle

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Prospective blinded study of somatic mutation detection in cell-free DNA utilizing a targeted 54-gene next generation sequencing panel in metastatic solid tumor patients von Kim, Seung Tae, Lee, Won-Suk, Lanman, Richard B, Mortimer, Stefanie, Zill, Oliver A, Kim, Kyoung-Mee, Jang, Kee Taek, Kim, Seok-Hyung, Park, Se Hoon, Park, Joon Oh, Park, Young Suk, Lim, Ho Yeong, Eltoukhy, Helmy, Kang, Won Ki, Lee, Woo Yong, Kim, Hee-Cheol, Park, Keunchil, Lee, Jeeyun, Talasaz, AmirAli

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Clinical utility of circulating cell-free DNA in advanced colorectal cancer von Pereira, Allan A Lima, Morelli, Maria Pia, Overman, Michael, Kee, Bryan, Fogelman, David, Vilar, Eduardo, Shureiqi, Imad, Raghav, Kanwal, Eng, Cathy, Manuel, Shanequa, Crosby, Shadarra, Wolff, Robert A, Banks, Kimberly, Lanman, Richard, Talasaz, AmirAli, Kopetz, Scott, Morris, Van

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Abstract 5705: Analytical validation of Guardant360 v2.10 von Vowles, James, Odegaard, Justin, Mortimer, Stefanie, Fairclough, Stephen, Sikora, Marcin, Abdueva, Diana, Mokhtari, Reza, Baca, Arthur, Talasaz, AmirAli

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Abstract 4343: Comparison of over 10,000 clinical NGS circulating tumor DNA profiles to tissue-derived genomic compendia von Zill, Oliver A., Banks, Kimberly C., Jackson, Coyt, Mortimer, Stefanie, Baca, Arthur, Nagy, Becky, Lanman, Richard B., Eltoukhy, Helmy, Talasaz, AmirAli

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Electrical detection of protein biomarkers using bioactivated microfluidic channels von Javanmard, Mehdi, Talasaz, Amirali H, Nemat-Gorgani, Mohsen, Pease, Fabian, Ronaghi, Mostafa, Davis, Ronald W

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