Human CD59 Incorporation into Porcine Endogenous Retrovirus Particles: Implications for the Use of Transgenic Pigs for Xenotransplantation von Takefman, Daniel M, Spear, Gregory T, Saifuddin, Mohammed, Wilson, Carolyn A

Volltext

Immune Complexes Containing Human Immunodeficiency Virus Type 1 Primary Isolates Bind to Lymphoid Tissue B Lymphocytes and Are Infectious for T Lymphocytes von Jakubik, J J, Saifuddin, M, Takefman, D M, Spear, G T

Volltext

Detection and Characterization of Porcine Endogenous Retrovirus in Porcine Plasma and Porcine Factor VIII von Takefman, D M, Wong, S, Maudru, T, Peden, K, Wilson, C A

Volltext

Detection of HIV-1 provirus in bronchoalveolar lavage cells by polymerase chain reaction von LANDAY, A. L, SCHADE, S. Z, TAKEFMAN, D. M, KUHNS, M. C, MCNAMARA, A. L, ROSEN, R. L, KESSLER, H. A, SPEAR, G. T

Volltext

Susceptibility of HIV-1 plasma virus to complement-mediated lysis. Evidence for a role in clearance of virus in vivo von Sullivan, BL, Knopoff, EJ, Saifuddin, M, Takefman, DM, Saarloos, MN, Sha, BE, Spear, GT

Volltext

HIV-1 strain dependence of complement-mediated virolysis induced by recombinant CD4-IgG von Spear, G T, Ghassemi, M, Takefman, D M

Volltext

Complement Can Neutralize HIV-1 Plasma Virus by a C5-Independent Mechanism von Sullivan, Brenda L., Takefman, Daniel M., Spear, Gregory T.

Volltext

Mechanisms of Resistance of HIV-1 Primary Isolates to Complement-Mediated Lysis von Takefman, Daniel M., Sullivan, Brenda L., Sha, Beverly E., Spear, Gregory T.

Volltext

Complement activation by human monoclonal antibodies to human immunodeficiency virus von SPEAR, G. T, TAKEFMAN, D. M, SULLIVAN, B. L, LANDAY, A. L, ZOLLA-PAZNER, S

Volltext

Antibodies to the HIV-1 V3 Loop in Serum from Infected Persons Contribute a Major Proportion of Immune Effector Functions Including Complement Activation, Antibody Binding, and Neu... von Spear, Gregory T., Takefman, Daniel M., Sharpe, Sandra, Ghassemi, Mahmood, Zolla-Pazner, Susan

Volltext

Infectivity of HIV immune complexes after binding to B cells via CR2 von Spear, Gregory T., Takefman, Daniel M., Saifuddin, Mohammed, Jakubik, Jocelyn J.

Volltext

Anti-cellular Antibodies in Sera from Vaccinated Macaques Can Induce Complement-Mediated Virolysis of Human Immunodeficiency Virus and Simian Immunodeficiency Virus von Spear, Gregory T., Takefman, Daniel M., Sullivan, Brenda L., Landay, Alan L., Jennings, Myra B., Carlson, James R.

Volltext

Hemophilia B Gene Therapy with a High-Specific-Activity Factor IX Variant von George, Lindsey A, Sullivan, Spencer K, Giermasz, Adam, Rasko, John E.J, Samelson-Jones, Benjamin J, Ducore, Jonathan, Cuker, Adam, Sullivan, Lisa M, Majumdar, Suvankar, Teitel, Jerome, McGuinn, Catherine E, Ragni, Margaret V, Luk, Alvin Y, Hui, Daniel, Wright, J. Fraser, Chen, Yifeng, Liu, Yun, Wachtel, Katie, Winters, Angela, Tiefenbacher, Stefan, Arruda, Valder R, van der Loo, Johannes C.M, Zelenaia, Olga, Takefman, Daniel, Carr, Marcus E, Couto, Linda B, Anguela, Xavier M, High, Katherine A

Volltext

A Phase 1/2 Trial of Investigational Spk-8011 in Hemophilia a Demonstrates Durable Expression and Prevention of Bleeds von High, Katherine A., George, Lindsey A., Eyster, M. Elaine, Sullivan, Spencer K., Ragni, Margaret V., Croteau, Stacy E., Samelson-Jones, Ben J., Evans, Matthew, Joseney-Antoine, Marcelyne, Macdougall, Amy, Kadosh, Judith, Runoski, Alexa R., Campbell-Baird, Cynthia, Douglas, Kayla, Tompkins, Summer, Hait, Howard, Couto, Linda B., Bassiri, Ashlyn Eaton, Valentino, Leonard A., Carr, Marcus E., Hui, Daniel J, Wachtel, Katie, Takefman, Daniel, Mingozzi, Federico, Anguela, Xavier M., Reape, Kathleen B

Volltext

Spk-8011: Preliminary Results from a Phase 1/2 Dose Escalation Trial of an Investigational AAV-Mediated Gene Therapy for Hemophilia a von George, Lindsey A., Ragni, Margaret V., Samelson-Jones, Ben J., Cuker, Adam, Runoski, Alexa R., Cole, Grace, Wright, Fraser, Chen, Yifeng, Hui, Daniel J, Wachtel, Katie, Takefman, Daniel, Couto, Linda B., Reape, Kathleen Z., Carr, Marcus E., Anguela, Xavier M., High, Katherine A.

Volltext

Spk-9001: Adeno-Associated Virus Mediated Gene Transfer for Hemophilia B - 1 Year Follow up and Impact of Baseline Characteristics on Transgene-Derived Factor IX Activity and Persi... von George, Lindsey A., Sullivan, Spencer K., Giermasz, Adam, Samelson-Jones, Ben J., Ducore, Jonathan M., Teitel, Jerome M., Cuker, Adam, Von Mackensen, Sylvia, Majumdar, Suvankar, McGuinn, Catherine E., Runoski, Alexa R., Wright, Fraser, Dasen, Sue, Barber, Kimberly, Chen, Yifeng, Hui, Daniel J., Patel, Ruchi, Liu, Yun, Wachtel, Katie, Takefman, Dan, Couto, Linda B., Reape, Kathleen Z., Carr, Marcus E., Anguela, Xavier M., High, Katherine A.

Volltext

Spk-9001: Adeno-Associated Virus Mediated Gene Transfer for Hemophilia B Achieves Sustained Mean Factor IX Activity Levels of >30% without Immunosuppression von George, Lindsey A., Sullivan, Spencer K., Giermasz, Adam, Ducore, Jonathan M., Teitel, Jerome M., Cuker, Adam, Sullivan, Lisa M., Majumdar, Suvankar, McGuinn, Catherine E., Galvao, Aline M., Luk, Alvin Y., Wright, J. Fraser, Chen, Yifeng, Hui, Daniel J., Wachtel, Katie, Urich, Teresa, Takefman, Daniel, Couto, Linda B., Carr, Marcus E., Anguela, Xavier M., High, Katherine A.

Volltext