Leptosins isolated from marine fungus Leptoshaeria species inhibit DNA topoisomerases I and/or II and induce apoptosis by inactivation of Akt/protein kinase B von Yanagihara, Miyako, Sasaki‐Takahashi, Noriko, Sugahara, Tetsuo, Yamamoto, Seiko, Shinomi, Masahito, Yamashita, Izumi, Hayashida, Masashi, Yamanoha, Banri, Numata, Atsushi, Yamori, Takao, Andoh, Toshiwo

Volltext

Ribozymes targeting serine/threonine kinase Akt1 sensitize cells to anticancer drugs von Yanagihara, Miyako, Katano, Masayoshi, Takahashi‐Sasaki, Noriko, Kimata, Kiyonori, Taira, Kazunari, Andoh, Toshiwo

Volltext

family of membrane proteins associated with presenilin expression and γ-secretase function von Araki, Wataru, Takahashi-Sasaki, Noriko, Chui, De-Hua, Saito, Shinya, Takeda, Kazuya, Shirotani, Keiro, Takahashi, Keikichi, Murayama, Kiyoko S, Kametani, Fuyuki, Shiraishi, Hirohisa, Komano, Hiroto, Tabira, Takeshi

Volltext

Identification and characterization of a novel human APH-1b splice variant lacking exon 4 von Saito, Shinya, Takahashi-Sasaki, Noriko, Araki, Wataru

Volltext

Characterization of APH-1 mutants with a disrupted transmembrane GxxxG motif von Araki, Wataru, Saito, Shinya, Takahashi-Sasaki, Noriko, Shiraishi, Hirohisa, Komano, Hiroto, Murayama, Kiyoko S

Volltext