Establishment of Immunodeficient Retinal Degeneration Model Mice and Functional Maturation of Human ESC-Derived Retinal Sheets after Transplantation von Iraha, Satoshi, Tu, Hung-Ya, Yamasaki, Suguru, Kagawa, Takahiro, Goto, Motohito, Takahashi, Riichi, Watanabe, Takehito, Sugita, Sunao, Yonemura, Shigenobu, Sunagawa, Genshiro A., Matsuyama, Take, Fujii, Momo, Kuwahara, Atsushi, Kishino, Akiyoshi, Koide, Naoshi, Eiraku, Mototsugu, Tanihara, Hidenobu, Takahashi, Masayo, Mandai, Michiko

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Establishment of an integrated automated embryonic manipulation system for producing genetically modified mice von Eto, Tomoo, Ueda, Hiroki, Ito, Ryoji, Takahashi, Tsukasa, Watanabe, Toshiaki, Goto, Motohito, Sotomaru, Yusuke, Tanaka, Nobuaki, Takahashi, Riichi

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Generation of hypoimmunogenic T cells from genetically engineered allogeneic human induced pluripotent stem cells von Wang, Bo, Iriguchi, Shoichi, Waseda, Masazumi, Ueda, Norihiro, Ueda, Tatsuki, Xu, Huaigeng, Minagawa, Atsutaka, Ishikawa, Akihiro, Yano, Hisashi, Ishi, Tomoko, Ito, Ryoji, Goto, Motohito, Takahashi, Riichi, Uemura, Yasushi, Hotta, Akitsu, Kaneko, Shin

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rasH2 mouse: reproducibility and stability of carcinogenicity due to a standardized production and monitoring system von Tsutsumi, Hideki, Inoue, Ryo, Yasuda, Masahiko, Takahashi, Riichi, Suzuki, Masami, Urano, Koji

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Identification of gene mutations associated with the phenotype of short-limb mice emerging from a foundation colony of severely immunodeficient mice von KANEKO, Yui, TOMIYAMA, Kayo, YASUDA, Masahiko, KOMAKI, Yuji, OGURA, Tomoyuki, TAKAHASHI, Riichi, YAMAMOTO, Masafumi

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Humanized liver TK-NOG mice with functional deletion of hepatic murine cytochrome P450s as a model for studying human drug metabolism von Uehara, Shotaro, Iida, Yuichi, Ida-Tanaka, Miyuki, Goto, Motohito, Kawai, Kenji, Yamamoto, Masafumi, Higuchi, Yuichiro, Ito, Satoshi, Takahashi, Riichi, Kamimura, Hidetaka, Ito, Mamoru, Yamazaki, Hiroshi, Oshimura, Mitsuo, Kazuki, Yasuhiro, Suemizu, Hiroshi

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Creation of an experimental rearing environment for microbiome animal research using an individually ventilated cage system and bioBUBBLE enclosure von Ka, Yuyo, Ogura, Tomoyuki, Tomiyama, Kayo, Ueno, Masami, Nozu, Ryoko, Tsuruzono, Nobuyuki, Nozawa, Yuya, Hamano, Mariko, Takakura, Akira, Takahashi, Riichi

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Improvement of multilineage hematopoiesis in hematopoietic stem cell-transferred c-kit mutant NOG-EXL humanized mice von Ito, Ryoji, Ohno, Yusuke, Mu, Yunmei, Ka, Yuyo, Ito, Shuko, Emi-Sugie, Maiko, Mochizuki, Misa, Kawai, Kenji, Goto, Motohito, Ogura, Tomoyuki, Takahashi, Riichi, Niwa, Akira, Nakahata, Tatsutoshi, Ito, Mamoru

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Establishment of a human microbiome- and immune system-reconstituted dual-humanized mouse model von Ka, Yuyo, Ito, Ryoji, Nozu, Ryoko, Tomiyama, Kayo, Ueno, Masami, Ogura, Tomoyuki, Takahashi, Riichi

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Improved engraftment of human peripheral blood mononuclear cells in NOG MHC double knockout mice generated using CRISPR/Cas9 von Ka, Yuyo, Katano, Ikumi, Nishinaka, Eiko, Welcker, Jochen, Mochizuki, Misa, Kawai, Kenji, Goto, Motohito, Tomiyama, Kayo, Ogura, Tomoyuki, Yamamoto, Taichi, Ito, Mamoru, Ito, Ryoji, Takahashi, Riichi

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Host-microbe cross-talk governs amino acid chirality to regulate survival and differentiation of B cells von Suzuki, M., Sujino, T., Chiba, S., Harada, Y., Goto, M., Takahashi, R., Mita, M., Hamase, K., Kanai, T., Ito, M., Waldor, M. K., Yasui, M., Sasabe, J.

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Novel biomarker for detecting human-specific hepatocyte injury in humanized liver mouse model von Suemizu, Hiroshi, Yoneda, Nao, Kawai, Kenji, Nishiwaki, Megumi, Takahashi, Riichi

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Establishment of albumin-deficient NOG mice as a useful model for drug discovery research von Suemizu, Hiroshi, Ando, Yasuhiko, Yoneda, Masafumi Yamamoto, Goto, Motohito, Uehara, Shotaro, Takahashi, Riichi

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Strain preservation of experimental animals: Vitrification of two-cell stage embryos for multiple mouse strains von Eto, Tomoo, Takahashi, Riichi, Kamisako, Tsutomu

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A study on cryoprotectant solution suitable for vitrification of rat two-cell stage embryos von Eto, Tomoo, Takahashi, Riichi, Kamisako, Tsutomu, Hioki, Kyoji, Sotomaru, Yusuke

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A humanized mouse model to study asthmatic airway inflammation via the human IL-33/IL-13 axis von Ito, Ryoji, Maruoka, Shuichiro, Soda, Kaori, Katano, Ikumi, Kawai, Kenji, Yagoto, Mika, Hanazawa, Asami, Takahashi, Takeshi, Ogura, Tomoyuki, Goto, Motohito, Takahashi, Riichi, Toyoshima, Shota, Okayama, Yoshimichi, Izuhara, Kenji, Gon, Yasuhiro, Hashimoto, Shu, Ito, Mamoru, Nunomura, Satoshi

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Transgenic expression of the N525S-tuberin variant in Tsc2 mutant (Eker) rats causes dominant embryonic lethality von Shiono, Masatoshi, Kobayashi, Toshiyuki, Takahashi, Riichi, Ueda, Masatsugu, Ishioka, Chikashi, Hino, Okio

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Disruption of Genetic Interaction Between Two Autosomal Regions and the X Chromosome Causes Reproductive Isolation Between Mouse Strains Derived From Different Subspecies von Oka, Ayako, Aoto, Toshihiro, Totsuka, Yoshikazu, Takahashi, Riichi, Ueda, Masatsugu, Mita, Akihiko, Sakurai-Yamatani, Noriko, Yamamoto, Hiromi, Kuriki, Satoshi, Takagi, Nobuo, Moriwaki, Kazuo, Shiroishi, Toshihiko

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Human dendritic cell differentiation in hematopoietic stem cell-transplanted NOG hFLT3L Tg/mFlt3 KO humanized mice von Mu, Yunmei, Ohno, Yusuke, Mochizuki, Misa, Kawai, Kenji, Goto, Motohito, Ogura, Tomoyuki, Takahashi, Riichi, Ito, Mamoru, Ito, Ryoji

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Increase in the apparent intercalation ability of a platinum complex via multivalency by installation into the sidechain of a graft copolymer and observation of structural changes... von Osawa, Shigehito, Takahashi, Riichi, Watanabe, Remi, Kubo, Sayaka, Otsuka, Hidenori

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