Molecular mechanism of intramembrane proteolysis by γ-secretase von Tomita, Taisuke

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Secretase inhibitors and modulators for Alzheimer's disease treatment von Tomita, Taisuke

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Aberrant proteolytic processing and therapeutic strategies in Alzheimer disease von Tomita, Taisuke

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Mouse Models of Alzheimer's Disease von Yokoyama, Miyabishara, Kobayashi, Honoka, Tatsumi, Lisa, Tomita, Taisuke

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Sequential conformational changes in transmembrane domains of presenilin 1 in Aβ42 downregulation von Cai, Tetsuo, Tomita, Taisuke

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Molecular mechanisms of the genetic risk factors in pathogenesis of Alzheimer disease von Kanatsu, Kunihiko, Tomita, Taisuke

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Distinct Neurotoxic Effects of Extracellular Tau Species in Primary Neuronal-Glial Cultures von Pampuscenko, Katryna, Morkuniene, Ramune, Krasauskas, Lukas, Smirnovas, Vytautas, Tomita, Taisuke, Borutaite, Vilmante

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Structural Biology of Presenilins and Signal Peptide Peptidases von Tomita, Taisuke, Iwatsubo, Takeshi

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BORCS6 is involved in the enlargement of lung lamellar bodies in Lrrk2 knockout mice von Araki, Miho, Ito, Kyohei, Takatori, Sho, Ito, Genta, Tomita, Taisuke

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Pathogenic LRRK2 compromises the subcellular distribution of lysosomes in a Rab12‐RILPL1‐dependent manner von Ito, Kyohei, Araki, Miho, Katai, Yuta, Nishimura, Yuki, Imotani, Sota, Inoue, Haruki, Ito, Genta, Tomita, Taisuke

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Seeded assembly in vitro does not replicate the structures of α‐synuclein filaments from multiple system atrophy von Lövestam, Sofia, Schweighauser, Manuel, Matsubara, Tomoyasu, Murayama, Shigeo, Tomita, Taisuke, Ando, Takashi, Hasegawa, Kazuko, Yoshida, Mari, Tarutani, Airi, Hasegawa, Masato, Goedert, Michel, Scheres, Sjors H. W.

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CD2-associated protein (CD2AP) overexpression accelerates amyloid precursor protein (APP) transfer from early endosomes to the lysosomal degradation pathway von Furusawa, Kotaro, Takasugi, Toshiyuki, Chiu, Yung-Wen, Hori, Yukiko, Tomita, Taisuke, Fukuda, Mitsunori, Hisanaga, Shin-ichi

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Specific mutations in presenilin 1 cause conformational changes in γ-secretase to modulate amyloid β trimming von Imai, So, Cai, Tetsuo, Yoshida, Chika, Tomita, Taisuke, Futai, Eugene

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Photo-oxygenation inhibits tau amyloid formation von Suzuki, Takanobu, Hori, Yukiko, Sawazaki, Taka, Shimizu, Yusuke, Nemoto, Yu, Taniguchi, Atsuhiko, Ozawa, Shuta, Sohma, Youhei, Kanai, Motomu, Tomita, Taisuke

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Histidine 131 in presenilin 1 is the pH-sensitive residue that causes the increase in Aβ42 level in acidic pH von Cai, Tetsuo, Hatano, Aki, Kanatsu, Kunihiko, Tomita, Taisuke

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Detection of amyloid plaques targeted by bifunctional USPIO in Alzheimer's disease transgenic mice using magnetic resonance microimaging von Wadghiri, Youssef Zaim, Li, Jialin, Wang, Jinhuan, Hoang, Dung Minh, Sun, Yanjie, Xu, Hong, Tsui, Wai, Li, Yongsheng, Boutajangout, Allal, Wang, Andrew, de Leon, Mony, Wisniewski, Thomas

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Protein trafficking and maturation regulate intramembrane proteolysis von Morohashi, Yuichi, Tomita, Taisuke

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Specific Mutations in Aph1 Cause γ-Secretase Activation von Watanabe, Hikari, Yoshida, Chika, Hidaka, Masafumi, Ogawa, Tomohisa, Tomita, Taisuke, Futai, Eugene

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Human tauopathy-derived tau strains determine the substrates recruited for templated amplification von Tarutani, Airi, Miyata, Haruka, Nonaka, Takashi, Hasegawa, Kazuko, Yoshida, Mari, Saito, Yuko, Murayama, Shigeo, Robinson, Andrew C., Mann, David M. A., Tomita, Taisuke, Hasegawa, Masato

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Novel aspects of the phosphorylation and structure of pathological tau: implications for tauopathy biomarkers von Kimura, Taeko, Sato, Haruaki, Kano, Maria, Tatsumi, Lisa, Tomita, Taisuke

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