Expansion of chemical space for collaborative lead generation and drug discovery: the European Lead Factory Perspective von Karawajczyk, Anna, Giordanetto, Fabrizio, Benningshof, Jorg, Hamza, Daniel, Kalliokoski, Tuomo, Pouwer, Kees, Morgentin, Remy, Nelson, Adam, Müller, Gerhard, Piechot, Alexander, Tzalis, Dimitrios

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A Versatile Strategy for the Synthesis of 4,5-Dihydroxy-2,3-Pentanedione (DPD) and Related Compounds as Potential Modulators of Bacterial Quorum Sensing von Stotani, Silvia, Gatta, Viviana, Medda, Federico, Padmanaban, Mohan, Karawajczyk, Anna, Tammela, Päivi, Giordanetto, Fabrizio, Tzalis, Dimitrios, Collina, Simona

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IMI European Lead Factory — democratizing access to high-throughput screening von Jones, Philip S., Boucharens, Sylviane, McElroy, Stuart P., Morrison, Angus, Honarnejad, Saman, van Boeckel, Stan, van den Hurk, Helma, Basting, Daniel, Hüser, Jörg, Jaroch, Stefan, Ottow, Eckhard, Benningshof, Jorg, Folmer, Rutger H. A., Leemhuis, Frank, Kramer-Verhulst, Patricia M., Nies, Vera J. M., Orrling, Kristina M., Rijnders, Ton, Pfander, Claudia, Engkvist, Ola, Pairaudeau, Garry, Simpson, Peter B., Ortholand, Jean-Yves, Roche, Didier, Dömling, Alexander, Kühnert, Sven M., Roevens, Peter W. M., van Vlijmen, Herman, van Wanrooij, Eva J. A., Verbruggen, Christophe, Nussbaumer, Peter, Ovaa, Huib, van der Stelt, Mario, Simonsen, Klaus Baek, Tagmose, Lena, Waldmann, Herbert, Duffy, James, Finsinger, Dirk, Jurzak, Mirek, Burgess-Brown, Nicola A., Lee, Wen H., Rutjes, Floris P. J. T., Haag, Hubert, Kallus, Christopher, Mors, Hartmut, Dorval, Thierry, Lesur, Brigitte, Ramon Olayo, Fernando, Hamza, Daniel, Jones, Geraint, Pearce, Christopher, Piechot, Alexander, Tzalis, Dimitrios, Clausen, Mads H., Davis, Jeremy, Derouane, Daphné, Vermeiren, Céline, Kaiser, Markus, Stockman, Robert A., Barrault, Denise V., Pannifer, Andrew D., Swedlow, Jason R., Nelson, Adam S., Orru, Romano V. A., Ruijter, Eelco, van Helden, Steven P., Li, Volkhart M., Vries, Ton, de Vlieger, Jon S. B.

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Cesium Hydroxide: A Superior Base for the Catalytic Alkynylation of Aldehydes and Ketones and Catalytic Alkenylation of Nitriles von Tzalis, Dimitrios, Knochel, Paul

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Clinical candidates modulating protein-protein interactions: The fragment-based experience von Valenti, Dario, Hristeva, Stanimira, Tzalis, Dimitrios, Ottmann, Christian

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Fragment‐Based Stabilizers of Protein–Protein Interactions through Imine‐Based Tethering von Wolter, Madita, Valenti, Dario, Cossar, Peter J., Levy, Laura M., Hristeva, Stanimira, Genski, Thorsten, Hoffmann, Torsten, Brunsveld, Luc, Tzalis, Dimitrios, Ottmann, Christian

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Interrogating dense ligand chemical space with a forward-synthetic library von Chevillard, Florent, Stotani, Silvia, Karawajczyk, Anna, Hristeva, Stanimira, Pardon, Els, Steyaert, Jan, Tzalis, Dimitrios, Kolb, Peter

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An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3‑3 Interaction with NF-κBUtilizing a Reversible Covalent Tethering Approach von Wolter, Madita, Valenti, Dario, Cossar, Peter J, Hristeva, Stanimira, Levy, Laura M, Genski, Thorsten, Hoffmann, Torsten, Brunsveld, Luc, Tzalis, Dimitrios, Ottmann, Christian

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Gemeinsam mehr Wirkstoffe von Tzalis, Dimitrios

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Coordination compounds as building blocks: single-step synthesis of multi-ruthenium(II) complexes von Tzalis, Dimitrios, Tor, Yitzhak

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Fragment-Based Interrogation of the 14–3–3/TAZ Protein–Protein Interaction von Andlovic, Blaž, Valenti, Dario, Centorrino, Federica, Picarazzi, Francesca, Hristeva, Stanimira, Hiltmann, Malgorzata, Wolf, Alexander, Cantrelle, François-Xavier, Mori, Mattia, Landrieu, Isabelle, Levy, Laura M., Klebl, Bert, Tzalis, Dimitrios, Genski, Thorsten, Eickhoff, Jan, Ottmann, Christian

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Ru-Centered coordination complexes as a new phase transfer catalyst for alkylation of enolates and Michael additions von Tzalis, Dimitrios, Knochel, Paul

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Simple one-step synthesis of 3-bromo- and 3,8-dibromo-1,10-phenanthroline: Fundamental building blocks in the design of metal chelates von Tzalis, Dimitrios, Tor, Yitzhak, Salvatorre, Failla, Jay Siegel, S

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Set-up and screening of a fragment library targeting the 14-3-3 protein interface von Valenti, Dario, Neves, João Filipe, Cantrelle, François-Xavier, Hristeva, Stanimira, Lentini Santo, Domenico, Obšil, Tomáš, Hanoulle, Xavier, Levy, Laura M, Tzalis, Dimitrios, Landrieu, Isabelle, Ottmann, Christian

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Gemeinsam mehr Wirkstoffe von Tzalis, Dimitrios

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Set-up and screening of a fragment library targeting the 14-3-3 protein interface† †Electronic supplementary information (ESI) available: Statistical analysis of the fragment colle... von Valenti, Dario, Neves, João Filipe, Cantrelle, François-Xavier, Hristeva, Stanimira, Lentini Santo, Domenico, Obšil, Tomáš, Hanoulle, Xavier, Levy, Laura M., Tzalis, Dimitrios, Landrieu, Isabelle, Ottmann, Christian

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Cesium hydroxide catalyzed addition of alcohols and amine derivatives to alkynes and styrene von Tzalis, Dimitrios, Koradin, Christopher, Knochel, Paul

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The European Lead Factory: A Blueprint for Public-Private Partnerships in Early Drug Discovery von Karawajczyk, Anna, Orrling, Kristina M, de Vlieger, Jon S B, Rijnders, Ton, Tzalis, Dimitrios

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Fragment‐Based Stabilizers of Protein–Protein Interactions through Imine‐Based Tethering von Wolter, Madita, Valenti, Dario, Cossar, Peter J., Levy, Laura M., Hristeva, Stanimira, Genski, Thorsten, Hoffmann, Torsten, Brunsveld, Luc, Tzalis, Dimitrios, Ottmann, Christian

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Stereochemically-Defined Supramolecular Architectures:  Diastereomerically-Pure Multi-Ru II Complexes von Tzalis, Dimitrios, Tor, Yitzhak

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